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L-Sulforaphane

CAS No.
142825-10-3
Chemical Name:
L-Sulforaphane
Synonyms
Broccoli seed extract;NSC47734;NSC 47734;NSC-47734;sulphorane;L-Sulforafan;L-SULFORAPHAN;S-SULFORAPHANE;R-SULFORAPHANE;D-SULFORAPHANE
CBNumber:
CB6765543
Molecular Formula:
C6H11NOS2
Molecular Weight:
177.29
MDL Number:
MFCD09039283
MOL File:
142825-10-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-11-04 17:04:01

L-Sulforaphane Properties

Boiling point 368.2±25.0 °C(Predicted)
Density 1.17±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: 40 mg/mL, soluble
form liquid
color slightly yellow
optical activity [α]/D -70 to -90°, c =1.0 in chloroform-d
InChI InChI=1S/C6H11NOS2/c1-10(8)5-3-2-4-7-6-9/h2-5H2,1H3/t10-/m1/s1
InChIKey SUVMJBTUFCVSAD-UHFFFAOYSA-N
SMILES C(N=C=S)CCC[S@@](C)=O
FDA UNII GA49J4310U
Comptox DTXSID DTXSID40162196
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H315-H319-H334-H335
Precautionary statements  P501-P261-P270-P271-P264-P280-P284-P302+P352-P342+P311-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P310+P330-P304+P340+P312-P403+P233-P405
PPE Eyeshields, Gloves
Safety Statements  23-24/25-22
WGK Germany  3
HS Code  29309090
Storage Class 11 - Combustible Solids
NFPA 704
3
2 0

L-Sulforaphane price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S6317 L-Sulforaphane ≥95% (HPLC), oil 142825-10-3 5mg $308 2026-04-30 Buy
Cayman Chemical 14797 L-Sulforaphane ≥98% 142825-10-3 1mg $50 2026-04-30 Buy
Cayman Chemical 14797 L-Sulforaphane ≥98% 142825-10-3 5mg $123 2026-04-30 Buy
Cayman Chemical 14797 L-Sulforaphane ≥98% 142825-10-3 10mg $195 2026-04-30 Buy
Cayman Chemical 14797 L-Sulforaphane ≥98% 142825-10-3 50mg $768 2026-04-30 Buy
Product number Packaging Price Buy
S6317 5mg $308 Buy
14797 1mg $50 Buy
14797 5mg $123 Buy
14797 10mg $195 Buy
14797 50mg $768 Buy

L-Sulforaphane Chemical Properties, Uses, Production

Description

Sulforaphane is a naturally-occurring phytochemical belonging to the class of isothiocyanates. As the aglycone metabolite of glucosinolate glucoraphanin (sulforaphane glucosinolate), sulforaphane acts as an antioxidant and potent stimulator of endogenous detoxifying enzymes. This agent displays anticarcinogenic properties due to its ability to induce phase II detoxification enzymes, such as glutathione S-transferase and quinone reductase, thereby providing protection against certain carcinogens and toxic, reactive oxygen species. Broccoli sprouts contain large amounts of sulforaphane, which is also found in other cruciferous vegetables including cabbage and kale.

Chemical Properties

L-Sulforaphane is a clear Pale Yellow Oil and It is an isothiocyanate derived from the natural compound glucoraphanin, which is abundant in cruciferous vegetables, including broccoli. soluble in methanol, ethanol, DMSO and other organic solvents.

Uses

L-sulforaphane is an Antitumor agent and has antioxidant, anti-cancer, anti-ultraviolet, help clear lung bacteria, and prevent gout. It was found to inhibit chemically induced mammary tumor formation in rats. L-Sulforaphane has been reported to prevent NFκB binding, which results in downregulation of apoptosis inhibitors therefore inducing apoptosis. It also displays a capacity to inhibit intracellular, extracellular, and antibiotic-resistant strains of Helicobacter pylori. Additionally, L-Sulforaphane has been found to prevent clonogenicity. This Sulforaphane is sold in the L-enantiomer form.

Application

L-Sulforaphane was used to study Nrf2-mediated signaling in mouse primary preadipocytes and murine macrophage RAW 264.7 cell line.

Definition

ChEBI: (R)-sulforaphane is a sulforaphane in which the sulfinyl group has R configuration. Naturally occurring compound found in brocolli that acts as a (R)-sulforaphane is a sulforaphane in which the sulfinyl group has R configuration. Naturally occurring compound found in brocolli that acts as a potent inducer of phase II detoxification enzymes. It is an enantiomer of a (S)-sulforaphane.potent inducer of phase II detoxification enzymes. It is an enantiomer of a (S)-sulforaphane.

Biochem/physiol Actions

L-Sulforaphane is a potent, selective inducer of phase II detoxification enzymes with anticarcinogenic properties. Organosulfur compound found in cruciferous vegetables, including broccoli.
Sulforaphane is an anti-cancer, anti-microbial and anti-diabetic compound found in cruciferous vegetables. It induces the production of detoxifying enzymes such as quinone reductase and glutathione S-transferase that cause xenobiotic transformation. Sulforaphane also increases the transcription of tumor suppressor proteins and inhibits histone deacetylases. It modulates inflammatory responses by suppressing the LPS-mediated expression of iNOS, COX-2, IL-1β and TNF-α.

52096-68-1
142825-10-3
Synthesis of L-Sulforaphane from N-(4-methylsulfanyl-butyl)phthalimide

L-Sulforaphane Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 175)
Supplier Tel Email Country ProdList Advantage
Shanghai Mokai Pharmaceutical Technology Co., Ltd. 021-60951261 18601606476;13003254593 nancy@mkpharma.cn China 453 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5994 61
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60
Chengdu Climax Biotech Co., Ltd. 028-83311324 1278112614 climaxbiotech@gmail.com China 925 58
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29975 65
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3984 66

Related articles

View Latest Price from L-Sulforaphane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-Sulforaphane pictures 2026-11-06 L-Sulforaphane
142825-10-3
1KG 0.6%-98% HP0LC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
(R)-Sulforaphane pictures 2026-07-27 (R)-Sulforaphane
142825-10-3
$57.00-137.00 99.39% 10g TargetMol Chemicals Inc.
Sulforaphane pictures 2026-05-22 Sulforaphane
142825-10-3
1kg 1%-10% 98% 1000 kg BINBOBIO CO., LTD.
  • L-Sulforaphane pictures
  • L-Sulforaphane
    142825-10-3
  • $0.00
  • 0.6%-98% HP0LC
  • Changsha Staherb Natural Ingredients Co., Ltd.

L-Sulforaphane Spectrum

(R)-1-ISOTHIOCYANATO-4-(METHYLSULFINYL)BUTANE R,S-SULFORAPHANE R-SULFORAPHANE S-SULFORAPHANE SULFORAPHANE, L- SULFORAPHANE, D- SULFORAPHANE, DL- 4-METHYLSULPHINYLBUTYLISOTHIOCYANATE L-SULFORAPHAN (R)-1-Isothiocyanato-4-(methylsulfinyl)butane, 4-Methylsulfinylbutyl isothiocyanate R-Sulforaphane (in ethanol) (+)-1-ISOTHIOCYANATE-4R(METHYLSULFINYL)-BUTANE 1-ISOTHIOCYANATO-4-(METHYLSULFIYL)-BUTANE ((-)1-ISOTHIOCYANATO-4R-METHYLSULFINYL)BUTANE (-)1-ISOTHIOCYANATO-4S-(METHYLSULFINYL)-BUTANE (+)1-ISOTHIOCYANATO-4S-(METHYLSULFINYL)-BUTANE 1-ISOTHISCYANATO-4-(METHYLSULFINYL)-BUTANE 4-METHYLSULFINYLBUTYL ISOTHIOCYANATE (-)-(4R)-SULFORAPHANE D-SULFORAPHANE DL-SULPHORAPHANE (-)-ISOTHIOCYANATO-(4R)-(METHYLSULFINYL)BUTANE L-SULFORAPHANE sulphorane Butane, 1-isothiocyanato-4-[(R)-methylsulfinyl]- Anazolenum natricum NSC 47734 NSC47734 NSC-47734 L-Sulforafan Brassica oleracea L.var.italic Planch. R-Sulforaphane, synthetic L-Sulforaphane Brocrene? Broccoli Extract(Sulforaphane) Sulforaphane ——Brassica oleracea italica Broccoli seed extract Rapeseed glucosinolate standard sample (R)-Sulforaphane (>90%) 142825-10-3 Chemopreventive Agents Cancer Research BioChemical Phase II Enzyme Inducers Aliphatics Chiral Reagents Inhibitors Sulfur & Selenium Compounds