8-Bromoquinolin-2(1H)-one
- CAS No.
- 67805-67-8
- Chemical Name:
- 8-Bromoquinolin-2(1H)-one
- Synonyms
- 8-bromoquinolin-2-ol;8-Bromo-1H-quinolin-2-one;8-Bromoquinolin-2(1H)-one;8-Bromo-2-hydroxyquinoline;8-BroMoquinoline-2(1h)-one;2(1H)-Quinolinone, 8-bromo-;8-Bromoquinolin-2(1H)-one98%;8-Bromoquinolin-2(1H)-one 98%;8-Bromo-1,2-dihydroquinolin-2-one;8-Bromo-1,2-dihydro-2-oxoquinoline
- CBNumber:
- CB6828617
- Molecular Formula:
- C9H6BrNO
- Molecular Weight:
- 224.05
- MDL Number:
- MFCD08741409
- MOL File:
- 67805-67-8.mol
- MSDS File:
- SDS
| Melting point | 196-198 °C |
|---|---|
| Boiling point | 390.2±42.0 °C(Predicted) |
| Density | 1.620±0.06 g/cm3(Predicted) |
| storage temp. | Room temperature. |
| pka | 10.70±0.70(Predicted) |
| form | Peachy beige fine crystalline needles |
| Appearance | Light yellow to light brown Solid |
| InChI | InChI=1S/C9H6BrNO/c10-7-3-1-2-6-4-5-8(12)11-9(6)7/h1-5H,(H,11,12) |
| InChIKey | HGJBIJWBYATVQY-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=CC=C2Br)C=CC1=O |
| UNSPSC Code | 12352116 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | WGK 3 |
| HS Code | 2933499090 |
| Storage Class | 11 - Combustible Solids |
8-Bromoquinolin-2(1H)-one price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | KOB0159 | 1-(2,3-Dihydro-1H-inden-2-yl)-2-methylpropan-2-amine hydrochloride | 67805-67-8 | 1g | $506 | 2026-04-30 | Buy |
| Biosynth | SCA80567 | 8-Bromoquinolin-2(1H)-one | 67805-67-8 | 10g | $584.1 | 2026-06-05 | Buy |
| Biosynth | SCA80567 | 8-Bromoquinolin-2(1H)-one | 67805-67-8 | 25g | $778.75 | 2026-06-05 | Buy |
| Biosynth | SCA80567 | 8-Bromoquinolin-2(1H)-one | 67805-67-8 | 50g | $973.5 | 2026-06-05 | Buy |
| Apolloscientific | OR8708 | 8-Bromoquinolin-2(1H)-one 98% | 67805-67-8 | 1g | $22 | 2026-06-04 | Buy |
8-Bromoquinolin-2(1H)-one Chemical Properties, Uses, Production
Uses
8-Bromoquinolin-2(1H)-one is an organic compound that inhibits the production of inflammatory substances in the body. It is a long-chain alkene and a synthetic substance that is used to prepare pharmaceuticals.
Application
8-Bromoquinolin-2(1H)-one has been shown to have anti-cancer properties, as well as an inhibitory effect on inflammation. The drug is synthesized by reacting benzonitrile with bromine and ammonia in a reaction system. 8-Bromoquinolin-2(1H)-one inhibits the synthesis of prostaglandin E2 (PGE2) by inhibiting cyclooxygenase and lipoxygenase enzymes. It also binds with high affinity to the enzyme phospholipase A 2 (PLA 2 ), which results in a rapid hydrolysis of phospholipids and production of arachidonic acid, which leads to increased levels of PGE2.
8-Bromoquinolin-2(1H)-one Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amkchem Limited | 微信：18019252918 18019252918 | sale@amkchem.com | China | 2060 | 58 |
| Nanjing Huarui Biopharmaceutical Technology Co., Ltd. | 18014824111 | 1623163500@qq.com | China | 341 | 58 |
| Hebei Fanbo Pharmaceutical Technology Co., Ltd. | 15588346797 | fanbomedical@163.com | China | 628 | 58 |
| Xi'an Huarui Zhiyuan Biotechnology Co., Ltd. | 18014474522 | 3487723181@qq.com | China | 1166 | 58 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Shanghai Paulshine Chemical Co., Ltd. | +86-021-37788663 | China | 186 | 64 | |
| Wuhan Shangrisyn chemicals Technology Co.,Ltd | 86-27-84466317 910021183 | China | 19 | 62 | |
| Atop-Pharma (Shanghai) Technology Co., Ltd. | +86 (21) 5196-9732 | China | 996 | 57 | |
| Chengdu Forest Science and Technology Development Co., Ltd. | 18030648795 18030648795 | sales@cdforestchem.com | China | 1995 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9510 | 58 |
View Latest Price from 8-Bromoquinolin-2(1H)-one manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | 8-bromo-1H-quinolin-2-one
67805-67-8
|
$5.50 | 1KG | 98%min | 1kg,10kg,100kg | Career Henan Chemical Co |
-
- 8-bromo-1H-quinolin-2-one
67805-67-8
- $5.50
- 98%min
- Career Henan Chemical Co
