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| | 8-Bromoquinolin-2(1H)-one Basic information |
| Product Name: | 8-Bromoquinolin-2(1H)-one | | Synonyms: | 8-Bromo-1,2-dihydroquinolin-2-one;8-bromoquinolin-2-ol;8-Bromo-2-hydroxyquinoline;8-Bromo-1,2-dihydro-2-oxoquinoline;8-Bromoquinolin-2(1H)-one 98%;8-BroMoquinoline-2(1h)-one;8-Bromo-1H-quinolin-2-one;8-Bromoquinolin-2(1H)-one98% | | CAS: | 67805-67-8 | | MF: | C9H6BrNO | | MW: | 224.05 | | EINECS: | | | Product Categories: | | | Mol File: | 67805-67-8.mol |  |
| | 8-Bromoquinolin-2(1H)-one Chemical Properties |
| Melting point | 196-198 °C | | Boiling point | 390.2±42.0 °C(Predicted) | | density | 1.620±0.06 g/cm3(Predicted) | | storage temp. | Room temperature. | | pka | 10.70±0.70(Predicted) | | form | Peachy beige fine crystalline needles | | Appearance | Light yellow to light brown Solid | | InChI | InChI=1S/C9H6BrNO/c10-7-3-1-2-6-4-5-8(12)11-9(6)7/h1-5H,(H,11,12) | | InChIKey | HGJBIJWBYATVQY-UHFFFAOYSA-N | | SMILES | N1C2=C(C=CC=C2Br)C=CC1=O |
| WGK Germany | WGK 3 | | HS Code | 2933499090 | | Storage Class | 11 - Combustible Solids |
| | 8-Bromoquinolin-2(1H)-one Usage And Synthesis |
| Uses | 8-Bromoquinolin-2(1H)-one is an organic compound that inhibits the production of inflammatory substances in the body. It is a long-chain alkene and a synthetic substance that is used to prepare pharmaceuticals. | | Application | 8-Bromoquinolin-2(1H)-one has been shown to have anti-cancer properties, as well as an inhibitory effect on inflammation. The drug is synthesized by reacting benzonitrile with bromine and ammonia in a reaction system. 8-Bromoquinolin-2(1H)-one inhibits the synthesis of prostaglandin E2 (PGE2) by inhibiting cyclooxygenase and lipoxygenase enzymes. It also binds with high affinity to the enzyme phospholipase A 2 (PLA 2 ), which results in a rapid hydrolysis of phospholipids and production of arachidonic acid, which leads to increased levels of PGE2. |
| | 8-Bromoquinolin-2(1H)-one Preparation Products And Raw materials |
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