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Monosodium glutamate

CAS No.
32221-81-1
Chemical Name:
Monosodium glutamate
Synonyms
DL-monosodium glutamate;sodium glutamate(1-);Monosodium glutamate;sodium acid l-glutamate;Monosodium DL-glutamate;UVZZAUIWJCQWEO-UHFFFAOYSA-N;Sodium 5-oxido-5-oxonorvaline;Monosodium glutamate USP/EP/BP;GlutaMic acid, sodiuMsalt (1:1);Sodium 2-amino-4-carboxybutanoate
CBNumber:
CB6875242
Molecular Formula:
C5H8NNaO4
Molecular Weight:
169.11109
MDL Number:
MOL File:
32221-81-1.mol
MSDS File:
SDS
Last updated:2026-07-01 20:51:29

Monosodium glutamate Properties

storage temp. 2-8°C, sealed storage, away from moisture and light
solubility Soluble in water and alcohol, not in oils
form crystallinepowder or small needles
color White
Odor faint, peptone-like odor
optical activity 22.43°(C=0.01g/ml 1N HCL)
Stability Stable. Incompatible with strong oxidizing agents
Major Application pharmaceutical small molecule
Cosmetics Ingredients Functions SKIN CONDITIONING
FRAGRANCE
HAIR CONDITIONING
CAS DataBase Reference 32221-81-1(CAS DataBase Reference)
FDA 21 CFR 155.120; 155.130; 155.170;155.200; 155.201; 161.190;169.140; 169.150
EWG's Food Scores 1
FDA UNII LX3YQ006AP
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

WGK Germany  WGK 2
Storage Class 11 - Combustible Solids

Monosodium glutamate price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2634 Monosodium Glutamate Pharmaceutical Secondary Standard; Certified Reference Material 32221-81-1 1G $358 2026-04-30 Buy
ChemScene CS-0255957 Glutamic acid sodium salt ≥98% 32221-81-1 25g $51 2026-06-04 Buy
ChemScene CS-0255957 Glutamic acid sodium salt ≥98% 32221-81-1 100g $136 2026-06-04 Buy
ChemScene CS-0255957 Glutamic acid sodium salt ≥98% 32221-81-1 500g $572 2026-06-04 Buy
aablocks AA01DO4G Sodium 2-amino-4-carboxybutanoate 98% 32221-81-1 1g $8 2026-05-29 Buy
Product number Packaging Price Buy
PHR2634 1G $358 Buy
CS-0255957 25g $51 Buy
CS-0255957 100g $136 Buy
CS-0255957 500g $572 Buy
AA01DO4G 1g $8 Buy

Monosodium glutamate Chemical Properties, Uses, Production

Description

Monosodium glutamate, known as MSG, is the sodium salt of the amino acid glutamic acid present in all protein. It is marketed as a white crystalline salt used to enhance fl avor as the monohydrate, C5H8NNaO4 H2O.There are two forms of glutamic acid: L-glutamic acid and D-glutamic acid. The natural glutamic acid found in humans and other higher organism is L-glutamic acid only, whereas processed monosodium glutamate contains both L-glutamic acid and D-glutamic acid along with pyroglutamic acid (C5H7NO3) and other contaminants.
Monosodium glutamate
Monosodium glutamate(MSG) is odorless and has little flavor. It works synergistically with other substances found in food proteins such as the nucleotides disodium 5'-inosine monophosphate (IMP) and disodium 5'-guanosine monophosphate (GMP), to produce a pleasing savory taste.

Chemical Properties

white crystalline solid

History

The use of Monosodium glutamate(MSG) as a flavor enhancer is attributed to Kikunae Ikeda (1864 1936), a chemistry professor from Tokyo Imperial University. Ikeda patented Monosodium glutamate(MSG) as a flavor enhancer along with processes used to produce it. The isolated glutamic acid was then purified and converted to MSG. The use of Monosodium glutamate(MSG) as a flavor enhancer began in Japan and Asia, but widespread use of the compound in the United States did not occur until after World War II. Ajinomoto started manufacturing Monosodium glutamate(MSG) in the United States in 1956 (Ajinomoto became affiliated with Kraft General Foods in 1973).

Uses

The safety of manufactured Monosodium glutamate(MSG) has been questioned for the last several decades. Conditions associated with Monosodium glutamate(MSG) symptom complex included numbness in the back of the neck, radiating to the arms; warmth and fatigue in the head, upper back, neck, and arms; facial pressure or tightness; chest pain; headache; nausea; and heart palpitations. There does not seem to be an absolute consensus on the safety of MSG, but for the most part Monosodium glutamate(MSG) is considered safe if consumed in normal quantities. An acceptable daily intake level is not cited by government regulators, but the average person consumes between 0.3 and 1.0 gram of Monosodium glutamate(MSG) daily. Estimates of annual global production of Monosodium glutamate(MSG) range between several hundred thousand tons to as high as 1 million tons. Although practically all Monosodium glutamate(MSG) produced is used in the food industry, a small portion is used for agricultural feed supplements (for swine), pesticides, and pharmaceuticals.

Uses

Monosodium glutamate (MSG) is a flavor enhancer that is the sodium salt of glutamic acid, an amino acid. It is a white crystal that is readily soluble in water. It intensifies and enhances flavor but does not contribute a flavor of its own. It may be present as one of the amino acids or in a free form, which is how it effectively enhances the flavor of foods. It is produced through a fermentation process of molasses. It is used at 0.1–1.0% in meats, soups, and sauces.

Definition

A white crystalline solid compound, made from soya-bean protein. It is a sodium salt of glutamic acid used as a flavor enhancer, particularly in Chinese cuisine. Monosodium glutamate can cause an allergic reaction in people who are ultrasensitive to it.

Global Suppliers ( 192)
Supplier Tel Email Country ProdList Advantage
VOT INTERNATIONAL BUSINESS CO.,LTD 0536-2456718 China 226 55
Hubei Jusheng Technology Co.,Ltd 027-59599241 18871490274 1400878000@qq.com China 9506 58
Chizhou Kailong Import and Export Trade Co., Ltd. xg01_gj@163.com China 9413 50
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9170 60
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shenzhen Simeiquan Biotechnology Co. Ltd 18126413629 0755-23311925 2355327053 abel@ycgmp.com China 5101 58
Shenzhen Sendi Biological Technology Co., Ltd. 18124570582 TEL:0755-23574479 2355327139 siliao02@yccreate.com China 6102 58
Wuhan Magic Biological Technology Co., Ltd. 18872289958、027-52304252、3400508168 3400508168@qq.com China 1901 55
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd. 027-50664929, 13971561712 hubxys2001@163.com China 1436 55
Shanghai Orgchem Co.,Ltd. +86-21-5877 1921 info@chemofchina.com China 9630 55

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View Latest Price from Monosodium glutamate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Monosodium glutamate pictures 2026-09-18 Monosodium glutamate
32221-81-1
$750.00-980.00 1ton 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Monosodium glutamate pictures 2026-09-18 Monosodium glutamate
32221-81-1
0.99 RongNa Biotechnology Co.,Ltd
Monosodium Glutamate pictures 2026-09-01 Monosodium Glutamate
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1kg 99 10tons Shaanxi TNJONE Pharmaceutical Co., Ltd
DL-monosodium glutamate sodium glutamate(1-) sodium acid l-glutamate Monosodium glutamate Sodium 5-oxido-5-oxonorvaline Monosodium glutamate with other flavour-enhancers α-Amiopetandioic acid monosodium salt Glutamic acid, monosodium salt, DL- Monosodium DL-glutamate GlutaMic acid, sodiuMsalt (1:1) UVZZAUIWJCQWEO-UHFFFAOYSA-N Monosodium glutamate Basic information Monosodium glutamate USP/EP/BP TIANFU-CHEM - Monosodium glutamate Sodium 2-amino-4-carboxybutanoate 32221-81-1 7235-40-12 32221-81-4 C5H8NNaO4H20