5,8-Dibromoisoquinoline
- CAS No.
- 81045-39-8
- Chemical Name:
- 5,8-Dibromoisoquinoline
- Synonyms
- 5,8-Dibromoisoquinoline;Isoquinoline, 5,8-dibromo-;5,8-Dibromoisoquinoline98%;5,8-Dibromoisoquinoline 98%;5,8-Dibromoisoquinoline ISO 9001：2015 REACH
- CBNumber:
- CB6957906
- Molecular Formula:
- C9H5Br2N
- Molecular Weight:
- 286.95
- MDL Number:
- MFCD03109888
- MOL File:
- 81045-39-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2933499090 | |||||||||
| NFPA 704 |
|
5,8-Dibromoisoquinoline price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR8298 | 5,8-Dibromoisoquinoline 97% | 81045-39-8 | 1g | $41 | 2026-06-04 | Buy |
| Apolloscientific | OR8298 | 5,8-Dibromoisoquinoline 97% | 81045-39-8 | 5g | $117 | 2026-06-04 | Buy |
| Activate Scientific | AS1278 | 5,8-(Dibromo)isoquinoline 98% | 81045-39-8 | 1g | $31 | 2026-06-04 | Buy |
| Activate Scientific | AS1278 | 5,8-(Dibromo)isoquinoline 98% | 81045-39-8 | 5g | $119 | 2026-06-04 | Buy |
| Activate Scientific | AS1278 | 5,8-(Dibromo)isoquinoline 98% | 81045-39-8 | 25g | $433 | 2026-06-04 | Buy |
5,8-Dibromoisoquinoline Chemical Properties, Uses, Production
Synthesis
119-65-3
81045-39-8
Isoquinoline (13a) (1.83 mL, 15.50 mmol) was slowly added dropwise to concentrated sulfuric acid (17 mL) at 0 °C while maintaining stirring. The reaction mixture was cooled to -25 °C, followed by the addition of sodium borohydride (6.34 g, 35.65 mmol) in batches, with the rate of addition controlled to maintain the reaction temperature between -25 °C and -20 °C. The reaction was continued for 1 hour at this temperature. After the reaction was continued at this temperature for 1 h, the reaction mixture was allowed to warm up naturally to room temperature. The reaction mixture was carefully poured into crushed ice and the pH was adjusted with concentrated aqueous ammonia solution to 7.0. The resulting slurry was stirred at 0°C for 1 hr and subsequently filtered and washed with ice water. The crude product was air dried and purified by column chromatography to afford 5,8-dibromoisoquinoline (13b) (2.5 g, 56%). Mass spectrum (EI) m/z: 286 ([M+1]+). 1H NMR (400 MHz, DMSO-d6) δ: 9.48 (s, 1H), 8.78 (d, J = 6 Hz, 1H), 8.06 (d, J = 8 Hz, 1H), 7.98 (dd, J = 6 Hz, J = 8 Hz, 2H).
References
[1] Organic Letters, 2017, vol. 19, # 1, p. 262 - 265
[2] Journal of Materials Chemistry C, 2015, vol. 3, # 22, p. 5835 - 5843
[3] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 16, p. 4026 - 4030
[4] Patent: WO2013/5157, 2013, A1. Location in patent: Page/Page column 36; 37
[5] Polymer, 2011, vol. 52, # 26, p. 6029 - 6036
5,8-Dibromoisoquinoline Preparation Products And Raw materials
5,8-Dibromoisoquinoline Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Chengdu Forest Science and Technology Development Co., Ltd. | 18030648795 18030648795 | sales@cdforestchem.com | China | 1996 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
View Latest Price from 5,8-Dibromoisoquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 5,8-Dibromoisoquinoline
81045-39-8
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2019-12-20 | 5,8-Dibromoisoquinoline
81045-39-8
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 5,8-Dibromoisoquinoline
81045-39-8
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 5,8-Dibromoisoquinoline
81045-39-8
- $1.00
- 99%
- Career Henan Chemical Co
