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ChemicalBook >> CAS DataBase List >>2-Naphthalenecarboxylic acid, 6-[(hydroxyimino)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)methyl]-

2-Naphthalenecarboxylic acid, 6-[(hydroxyimino)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)methyl]-

2-Naphthalenecarboxylic acid, 6-[(hydroxyimino)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)methyl]- Structure
2-Naphthalenecarboxylic acid, 6-[(hydroxyimino)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)methyl]- structure
CAS No.
110952-22-2
Chemical Name:
2-Naphthalenecarboxylic acid, 6-[(hydroxyimino)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)methyl]-
Synonyms
BMS-185354;2-Naphthalenecarboxylic acid, 6-[(hydroxyimino)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)methyl]-
CBNumber:
CB69770283
Molecular Formula:
C26H27NO3
Molecular Weight:
401.5
MDL Number:
MOL File:
110952-22-2.mol
Last updated:2025-04-18 09:52:33
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2-Naphthalenecarboxylic acid, 6-[(hydroxyimino)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)methyl]- Properties

Boiling point 578.7±50.0 °C(Predicted)
Density 1.17±0.1 g/cm3(Predicted)
pka 4.10±0.30(Predicted)

2-Naphthalenecarboxylic acid, 6-[(hydroxyimino)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)methyl]- Chemical Properties, Uses, Production

Uses

BMS-185354 is a selective RARγ activator with an EC50 value of 28 nM. BMS-185354 is promising for research of cancers[1].

IC 50

RXRγ: 28 nM (EC50)

References

[1] Ostrowski J, et al. Serine 232 and methionine 272 define the ligand binding pocket in retinoic acid receptor subtypes. J Biol Chem. 1998 Feb 6;273(6):3490-5. DOI:10.1074/jbc.273.6.3490

2-Naphthalenecarboxylic acid, 6-[(hydroxyimino)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Naphthalenecarboxylic acid, 6-[(hydroxyimino)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)methyl]- Suppliers

Global Suppliers ( 1)
Supplier Tel Email Country ProdList Advantage
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
Supplier Advantage
TargetMol 58

110952-22-2 (2-Naphthalenecarboxylic acid, 6-[(hydroxyimino)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)methyl]-) Related Search:

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Retinoic acid

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2-Naphthalenecarboxylic acid, 6-[(hydroxyimino)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)methyl]- BMS-185354 110952-22-2