XIAP Antibody
- CAS No.
- Chemical Name:
- XIAP Antibody
- Synonyms
- XIAP Antibody;Mouse Monoclonal XIAP Antibody
- CBNumber:
- CB6983200
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
XIAP Antibody price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb619389 | XIAP Antibody | 100μl | $360 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb570711 | XIAP Antibody | 50μg | $140 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb571853 | XIAP Antibody | 100μl | $380 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb570711 | XIAP Antibody | 100μg | $220 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb106468 | XIAP antibody Immunogen affinity purified | 20μl(Trial size) | $256.7 | 2021-12-16 | Buy |
XIAP Antibody Chemical Properties,Uses,Production
Source
Rabbit
Reactivity
Mouse;Rat;Monkey;Human
Background
The inhibitor of apoptosis protein family consists of an evolutionarily conserved group of apoptosis inhibitors containing a conserved 70 amino acid BIR domain. Human members of this family include c-IAP1, c-IAP2, XIAP, survivin, livin, and NAIP. Overexpression of IAP family members, particularly survivin and livin, in cancer cell lines and primary tumors suggests an important role for these proteins in cancer progression. In general, the IAP proteins function through direct interactions to inhibit the activity of several caspases, including caspase-3, caspase-7, and caspase-9. In addition, binding of IAP family members to the mitochondrial protein Smac blocks their interaction with caspase-9, thereby allowing the processing and activation of the caspase.
References
[1] Deveraux, Q.L. and Reed, J.C. (1999) Genes Dev 13, 239-52.
[2] Deveraux, Q.L. et al. (1998) EMBO J 17, 2215-23.
[3] Altieri, D.C. et al. (1999) Lab Invest 79, 1327-33.
[4] Tamm, I. et al. (2000) Clin Cancer Res 6, 1796-803.
[5] Kasof, G.M. and Gomes, B.C. (2001) J Biol Chem 276, 3238-46.
[6] Deveraux, Q.L. et al. (1997) Nature 388, 300-4.
XIAP Antibody Preparation Products And Raw materials
Raw materials
Preparation Products
XIAP Antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25030 | 58 |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | 6206333 13167063860 | anhua.mao@aladdin-e.com | China | 43293 | 58 |
