BAMIFYLLINE
- CAS No.
- 2016-63-9
- Chemical Name:
- BAMIFYLLINE
- Synonyms
- Bamiphylline;8102CB;8102 CB;CB-8102;Bax-2739Z;Bamifyllin;BAMIFYLLINE;8-BENZYL-7-(2-(HYDROXYETHYL)AMINO)ETHYL)THEOPHYLLINE;8-benzyl-7-(2-(N-ethyl-2-hydroxyethylamino)ethyl)theophylline;8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,6-dione
- CBNumber:
- CB7103685
- Molecular Formula:
- C20H27N5O3
- Molecular Weight:
- 385.46
- MDL Number:
- MFCD00867023
- MOL File:
- 2016-63-9.mol
| Melting point | 80-80.5° |
|---|---|
| Boiling point | 619.0±65.0 °C(Predicted) |
| Density | 1.25 |
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | Chloroform (Very Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 14.73±0.10(Predicted) |
| form | Solid |
| color | White to Pale Brown |
| Stability | Hygroscopic |
| FDA UNII | ZTY15D026H |
| ATC code | R03DA08 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
BAMIFYLLINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 442101 | Bamifylline | 2016-63-9 | 1mg | $333 | 2026-06-03 | Buy |
| Usbiological | 442101 | Bamifylline | 2016-63-9 | 10mg | $531 | 2026-06-03 | Buy |
| Biosynth | CAA01663 | Bamifylline | 2016-63-9 | 1mg | $250 | 2026-06-04 | Buy |
| Biosynth | CAA01663 | Bamifylline | 2016-63-9 | 5mg | $341.15 | 2026-06-04 | Buy |
| Biosynth | CAA01663 | Bamifylline | 2016-63-9 | 10mg | $545.6 | 2026-06-04 | Buy |
BAMIFYLLINE Chemical Properties,Uses,Production
Originator
Bamifylline,ZYF Pharm Chemical
Uses
Bronchodilator.
Uses
Bamifylline is a drug of the xanthine chemical class which acts as a selective adenosine A1 receptor antagonist.
Definition
ChEBI: Bamifylline is an oxopurine.
Manufacturing Process
A mixture of 100 kg of 8-benzyltheophilline, 36 L of N-ethylethanolamine, 300 L of 1,2-dichlorethane and 71 kg of sodium carbonate was refluxed for 24 hours. Then 36 L of N-ethylethanolamine was added and the reaction mixture was refluxed. After cooling to the mixture was added the water and hydrochloric acid. The organic phase was extracted with hydrochloric acid. The acidic phase was neutralized with sodium carbonate and the 7-(N-ethyl-N-β- hydroxyethylaminoethyl)-8-benzyltheophilline was extracted with dichloromethane. The solvent was evaporated and the free base of 7-(N-ethyl- N-β-hydroxyethylaminoethyl)-8-benzyltheophilline was dissolved in methanol. Hydrochloride of 7-(N-ethyl-N-β-hydroxyethylaminoethyl)-8-benzyltheophilline was obtained by addition to the solution the hydrochloric acid; yield 81%, melting point 185-186°C.
Therapeutic Function
Bronchodilator, Coronary vasodilator
BAMIFYLLINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Sichuan Guanghan Bio-Tech Co., Ltd | +86-28-86127071 | info@sino-produce.com | China | 400 | 66 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3836 | 58 |
| Wuhan Taiyicheng Biopharmaceutical Co., Ltd. | 027-88320699 | tycshyy@126.com | China | 297 | 66 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Chizhou Kailong Import and Export Trade Co., Ltd. | xg01_gj@163.com | China | 9413 | 50 | |
| Shanghai Synchem Pharma Co., ltd | 21-619849051-1 18521059765 | synchempharma@aliyun.com | China | 4988 | 55 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
