Pregn-4-ene-3,20-dione-2,2,4,6,6,21,21,21-d8, 11,17-dihydroxy-, (11β)-
- CAS No.
- 2479914-04-8
- Chemical Name:
- Pregn-4-ene-3,20-dione-2,2,4,6,6,21,21,21-d8, 11,17-dihydroxy-, (11β)-
- Synonyms
- D8-21-Deoxycortisol;21-Deoxycortisol-[d8] in Methanol;21-Deoxycortisol (2,2,4,6,6,21,21,21-D?, 97%);21-Deoxycortisol-D8 in Methanol, Concentration: 100μg/mL (Standard);Pregn-4-ene-3,20-dione-2,2,4,6,6,21,21,21-d8, 11,17-dihydroxy-, (11β)-
- CBNumber:
- CB710689137
- Molecular Formula:
- C21H30O4
- Molecular Weight:
- 346.47
- MDL Number:
- MOL File:
- 2479914-04-8.mol
- MSDS File:
- SDS
Pregn-4-ene-3,20-dione-2,2,4,6,6,21,21,21-d8, 11,17-dihydroxy-, (11β)- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 35556 | 21-Deoxycortisol-d8 ≥99%deuteratedforms(d1-d8) | 2479914-04-8 | 1mg | $263 | 2026-04-30 | Buy |
| Cayman Chemical | 35556 | 21-Deoxycortisol-d8 ≥99%deuteratedforms(d1-d8) | 2479914-04-8 | 5mg | $1052 | 2026-04-30 | Buy |
| TRC | TRC-D232606-5MG | 4-Pregnen-11Beta,17Alpha-diol-3,20-dione-2,2,4,6,6,21,21,21-d8 | 2479914-04-8 | 5mg | $351 | 2026-06-03 | Buy |
| TRC | TRC-D232606-10MG | 4-Pregnen-11Beta,17Alpha-diol-3,20-dione-2,2,4,6,6,21,21,21-d8 | 2479914-04-8 | 10mg | $587 | 2026-06-03 | Buy |
| ChemScene | CS-0380315 | 21-Deoxycortisol-d8 98.79% | 2479914-04-8 | 1mg | $265 | 2026-06-04 | Buy |
Pregn-4-ene-3,20-dione-2,2,4,6,6,21,21,21-d8, 11,17-dihydroxy-, (11β)- Chemical Properties, Uses, Production
Uses
21-Deoxycortisol-d8 is the deuterium labeled 21-Deoxycortisol. 21-Deoxycortisol is an endogenous metabolite. 21-Deoxycortisol is a sign of congenital adrenal hyperplasia[1].
Biological Activity
21-Deoxycortisol-d8 is intended for use as an internal standard for the quantification of 21-deoxycortisol by GC- or LC-MS. 21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal gland via 11-hydroxylation by 11β-hydroxylase.1,2 Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations in CYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies.
References
1.Fiet, J., Villette, J.-M., Galons, H., et al.The application of a new highly-sensitive radioimmunoassay for plasma 21-deoxycortisol to the detection of steroid-21-hydroxylase deficiencyAnn. Clin. Biochem.31(Pt. 1)56-64(1994) 2.Cristoni, S., Cuccato, D., Sciannamblo, M., et al.Analysis of 21-deoxycortisol, a marker of congenital adrenal hyperplasia, in blood by atmospheric pressure chemical ionization and electrospray ionization using multiple reaction monitoringRapid Commun. Mass Spectrom.18(1)77-82(2004)
Pregn-4-ene-3,20-dione-2,2,4,6,6,21,21,21-d8, 11,17-dihydroxy-, (11β)- Preparation Products And Raw materials
Raw materials
Preparation Products
Pregn-4-ene-3,20-dione-2,2,4,6,6,21,21,21-d8, 11,17-dihydroxy-, (11β)- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Artis Biotech Co. Ltd. | 18108108965 18108108965 | sales@artisbio.com | China | 2503 | 58 |
| ChengDu SinoStandards Bio-Tech Co.,Ltd. ， | 028-83243028 19136088901 | sinostandards@163.com | China | 4979 | 58 |
| Reer Technology (Shanghai) Co., LTD | 021-64400900 15800436310 | bessey@reertech.com | China | 4097 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 | offer.de@lgcgroup.com | China | 19036 | 58 |
| CHINA ISOTOPE CO., LIMITED | 02151600108 13062666369 | info@isotopechem.com | China | 4721 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Shanghai Beiwanta Biotechnology Co., Ltd. | 021-67187366 19901745723 | info@bwtlab.com | China | 9888 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | judy.xia@synzest.com | China | 12577 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
