4-Pyrimidinol, 6-amino-2-methoxy- (9CI)
- CAS No.
- 186435-66-5
- Chemical Name:
- 4-Pyrimidinol, 6-amino-2-methoxy- (9CI)
- Synonyms
- 2-methoxy-6-amino-4-pyrimidone;6-aMino-2-MethoxypyriMidin-4-ol;6-Amino-2-methoxy-4-pyrimidinol;4-Pyrimidinol, 6-amino-2-methoxy-;6-Amino-2-methoxy-4(3H)-pyrimidinone;4-Pyrimidinol, 6-amino-2-methoxy- (9CI);Carbamicacid,N-[2-(2-hydroxyethoxy)ethyl]-,1,3-dimethylethylester
- CBNumber:
- CB71082022
- Molecular Formula:
- C5H7N3O2
- Molecular Weight:
- 141.13
- MDL Number:
- MFCD00068842
- MOL File:
- 186435-66-5.mol
- MSDS File:
- SDS
4-Pyrimidinol, 6-amino-2-methoxy- (9CI) price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS48373 | 6-Amino-2-methoxypyrimidin-4-ol 98% | 186435-66-5 | 1g | $68 | 2026-06-04 | Buy |
| Activate Scientific | AS48373 | 6-Amino-2-methoxypyrimidin-4-ol 98% | 186435-66-5 | 5g | $187 | 2026-06-04 | Buy |
| Activate Scientific | AS48373 | 6-Amino-2-methoxypyrimidin-4-ol 98% | 186435-66-5 | 25g | $700 | 2026-06-04 | Buy |
| aablocks | AA00ANUR | 6-Amino-2-Methoxypyrimidin-4-Ol 95% | 186435-66-5 | 1g | $29 | 2026-05-28 | Buy |
| aablocks | AA00ANUR | 6-Amino-2-Methoxypyrimidin-4-Ol 95% | 186435-66-5 | 5g | $79 | 2026-05-28 | Buy |
4-Pyrimidinol, 6-amino-2-methoxy- (9CI) Chemical Properties, Uses, Production
Synthesis
52328-05-9
105-56-6
186435-66-5
Synthesis of 6-amino-2-methoxy-4-pyrimidinone (compound a): was carried out with reference to the method described by W. Pfleiderer (Chem. Ber., 90: 2272 (1957). The steps were as follows: sodium methanol solution was prepared by dissolving sodium metal (15 g, 652 mmol) in 200 mL of methanol in batches. To this solution, O-methylisourea sulfate (30.6 g, 248 mmol) and ethyl cyanoacetate (30 g, 265 mmol) were added sequentially. The reaction mixture was heated to reflux and stirred continuously for 4.5 hours. After completion of the reaction, the mixture was cooled to room temperature, the solid product was collected by filtration and the solid was washed with a small amount of methanol. The filtrate and washings were combined and concentrated to dryness under reduced pressure to give a white solid residue. The residue was dissolved in 300 mL of hot water and the pH of the solution was adjusted with acetic acid to 7. Subsequently, the precipitated solid was filtered, washed with water, and dried to give 28 g (80% yield) of the target product, 6-amino-2-methoxy-4-pyrimidinone, as a white solid.
References
[1] Patent: US2003/181719, 2003, A1
4-Pyrimidinol, 6-amino-2-methoxy- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
4-Pyrimidinol, 6-amino-2-methoxy- (9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChangZhou SIDU chemical Co., Ltd. | 0519-81291281 18015082300 | siduchem@hotmail.com | China | 274 | 62 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 86(512)5235 8471 17715136450 | sales@shiyabiopharm.com | China | 4167 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
| Shanghai Tombiopharma Chemical Co. Ltd. | 13391076197 | tombiopharma@163.com | China | 4986 | 55 |
| DebyeTec.com Inc. | 18086626237 18086626237 | 2693528373@qq.com | China | 2935 | 56 |
| Shijiazhuang Jing Kang Technology Co.Ltd. | 13933818572 | 1519554262@qq.com | China | 1785 | 58 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
| Yujinpharma(Tianjin) Technology Co.,Ltd. | 13370351217 kungfu1217@1 | kungfu1217@163.com | China | 7991 | 58 |
| SuZhou Medinoah Co.,LTD. | 0512-69561983 13914027025 | zhang_q@medinoah.com | China | 3925 | 58 |
