ChemicalBook >> CAS DataBase List >>2-Furansulfonamide, N-[[(3,5-dimethylphenyl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-, sodium salt, ion(1-) (1:1)

2-Furansulfonamide, N-[[(3,5-dimethylphenyl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-, sodium salt, ion(1-) (1:1)

2-Furansulfonamide, N-[[(3,5-dimethylphenyl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-, sodium salt, ion(1-) (1:1) structure

CAS No.: 2768759-64-2

Chemical Name:: 2-Furansulfonamide, N-[[(3,5-dimethylphenyl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-, sodium salt, ion(1-) (1:1)

Synonyms: Inflammasome Inhibitor 4b

CBNumber:: CB712129295

Molecular Formula:: C16H19N2O5S.Na

Molecular Weight:: 374.39

MDL Number:

MOL File:: 2768759-64-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:52

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2-Furansulfonamide, N-[[(3,5-dimethylphenyl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-, sodium salt, ion(1-) (1:1) Properties

storage temp.	Store at -20°C
solubility	DMSO: soluble
form	A crystalline solid

2-Furansulfonamide, N-[[(3,5-dimethylphenyl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-, sodium salt, ion(1-) (1:1) price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	37030	Inflammasome Inhibitor 4b ≥98%	2768759-64-2	1mg	$119	2026-04-30	Buy
ChemScene	CS-0459578	NLRP3-IN-9	2768759-64-2	500??g	$161	2026-06-04	Buy
ChemScene	CS-0459578	NLRP3-IN-9	2768759-64-2	1mg	$258	2026-06-04	Buy
aablocks	AA027J8S	Inflammasome Inhibitor 4b ≥98%	2768759-64-2	1mg	$119	2026-06-02	Buy
Arctom	HY-146802	NLRP3-IN-9	2768759-64-2	500??g	$142	2026-05-26	Buy

Product number	Packaging	Price	Buy
37030	1mg	$119	Buy
CS-0459578	500??g	$161	Buy
CS-0459578	1mg	$258	Buy
AA027J8S	1mg	$119	Buy
HY-146802	500??g	$142	Buy

2-Furansulfonamide, N-[[(3,5-dimethylphenyl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-, sodium salt, ion(1-) (1:1) Chemical Properties,Uses,Production

Uses

NLRP3-IN-9 is a potent NLRP3 inhibitor. NLRP3-IN-9 inhibits IL-1β release. NLRP3-IN-9 reduces inflammation and mechanical hyperalgesia. NLRP3-IN-9 has the potential for the research of gout[1].

in vivo

NLRP3-IN-9 (3, 10 mg/kg; i.p.) reduces inflammation and mechanical hyperalgesia in a mouse model of acute gout^[1].

Animal Model:	3-4 month old male and female C57BL/6J WT and NLRP3-KO mice^[1]
Dosage:	3, 10 mg/kg
Administration:	I.p.
Result:	Reduced paw swelling by 40% in males and 33% in females at 3 mg/kg, and 66% in males and 52% in females at 10 mg/kg in WT mouse.

IC 50

NLRP3

References

[1] Narros-Fernández P, et al. Synthesis and Pharmacological Evaluation of New N-Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout. J Med Chem. 2022 Apr 28;65(8):6250-6260. DOI:10.1021/acs.jmedchem.2c00149

2-Furansulfonamide, N-[[(3,5-dimethylphenyl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-, sodium salt, ion(1-) (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

2-Furansulfonamide, N-[[(3,5-dimethylphenyl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-, sodium salt, ion(1-) (1:1) Suppliers

Global( 4)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11963	58

Supplier	Advantage
Shanghai Yifei Biotechnology Co. , Ltd.	58

2768759-64-2(2-Furansulfonamide, N-[[(3,5-dimethylphenyl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-, sodium salt, ion(1-) (1:1))Related Search:

NP3-146 sodium 2-Furansulfonamide, N-[[[4-chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-4-(1-hydroxy-1-methylethyl)- MCC950 CP-456773 sodium 2-Furansulfonamide, N-[[(3,5-dimethylphenyl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-, sodium salt, ion(1-) (1:1)

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Inflammasome Inhibitor 4b 2768759-64-2 C16H19N2NaO5S