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2-Ethyl-3,5-dimethylpyrazine

2-Ethyl-3,5-dimethylpyrazine structure

CAS No.: 27043-05-6

Chemical Name:: 2-Ethyl-3,5-dimethylpyrazine

Synonyms: 2,6-DIMETHYL-3-ETHYLPYRAZINE;FEMA 3149;FEMA NUMBER 3149;2-Ethyl-3,5-diMethyl;DIMETHYLETHYLPYRAZINE;2-ethyl-3,-dimethylpyrazine;2-ETHYL-3,5-DIMETHYLPYRAZINE;2-ethyl-3,?-dimethyl-pyrazin;3-ethyl-3,6-dimethyl-Pyrazine;2-ETHYL-3,5(6)-DIMETHYLPYRAZINE

CBNumber:: CB7133235

Molecular Formula:: C8H12N2

Molecular Weight:: 136.19

MDL Number:: MFCD00047392

MOL File:: 27043-05-6.mol

MSDS File:: SDS

Last updated:2026-01-13 11:24:29

Product description	Number	Pack Size	Price
2-Ethyl-3(5 or 6)-dimethylpyrazine, mixture of isomers ≥95%, FG	W314900	1 each	$58
2-Ethyl-3(5 or 6)-dimethylpyrazine, mixture of isomers FG	W314900	100g	$123
2-Ethyl-3(5 or 6)-dimethylpyrazine, mixture of isomers FG	W314900	250g	$188
2-Ethyl-3(5 or 6)-dimethylpyrazine, mixture of isomers FG	W314900	1kg	$721
2-Ethyl-3,5(6)-dimethylpyrazine, mixture of isomers analytical reference material	43236	100mg	$98.1
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2-Ethyl-3,5-dimethylpyrazine Properties

Boiling point	180-181 °C(lit.)
Density	0.965 g/mL at 25 °C(lit.)
FEMA	3149 \| 2-ETHYL-3,(5 OR 6)-DIMETHYLPYRAZINE
refractive index	n20/D 1.5015(lit.)
Flash point	157 °F
storage temp.	2-8°C
color	Colorless to Light yellow
Odor	at 0.10 % in dipropylene glycol. burnt coffee nutty roasted woody
Odor Type	burnt
biological source	synthetic
JECFA Number	775
Major Application	cleaning products cosmetics flavors and fragrances food and beverages personal care
Cosmetics Ingredients Functions	PERFUMING
InChI	1S/2C8H12N2/c1-4-8-7(3)10-6(2)5-9-8;1-4-8-7(3)9-5-6(2)10-8/h2*5H,4H2,1-3H3
InChIKey	BOFLOMVCGPWPQC-UHFFFAOYSA-N
SMILES	CCc1ncc(C)nc1C.CCc2nc(C)cnc2C
Substances Added to Food (formerly EAFUS)	2-ETHYL-3,(5 OR 6)-DIMETHYLPYRAZINE
CAS DataBase Reference	27043-05-6(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	R182EY5L8C
EPA Substance Registry System	Pyrazine, 2-ethyl-3,?-dimethyl- (27043-05-6)
UNSPSC Code	85151701
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P264-P270-P301+P312-P302+P352-P305+P351+P338

target organs

Respiratory system

Hazard Codes

Risk Statements

22-36/37/38

Safety Statements

WGK Germany

TSCA

TSCA listed

HS Code

2915.39.3500

Storage Class

10 - Combustible liquids

Hazard Classifications

Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	2
0		0

2-Ethyl-3,5-dimethylpyrazine price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	W314900	2-Ethyl-3(5 or 6)-dimethylpyrazine, mixture of isomers ≥95%, FG	27043-05-6	1 each	$58	2026-04-30	Buy
Sigma-Aldrich	W314900	2-Ethyl-3(5 or 6)-dimethylpyrazine, mixture of isomers FG	27043-05-6	100g	$123	2026-04-30	Buy
Sigma-Aldrich	W314900	2-Ethyl-3(5 or 6)-dimethylpyrazine, mixture of isomers FG	27043-05-6	250g	$188	2026-04-30	Buy
Sigma-Aldrich	W314900	2-Ethyl-3(5 or 6)-dimethylpyrazine, mixture of isomers FG	27043-05-6	1kg	$721	2026-04-30	Buy
Sigma-Aldrich	43236	2-Ethyl-3,5(6)-dimethylpyrazine, mixture of isomers analytical reference material	27043-05-6	100mg	$98.1	2026-04-30	Buy

Product number	Packaging	Price	Buy
W314900	1 each	$58	Buy
W314900	100g	$123	Buy
W314900	250g	$188	Buy
W314900	1kg	$721	Buy
43236	100mg	$98.1	Buy

2-Ethyl-3,5-dimethylpyrazine Chemical Properties,Uses,Production

Chemical Properties

clear light yellow liquid

Chemical Properties

2-Ethyl-3,(5 or 6)-dimethylpyrazine has a toasted nut, sweet woody, roasted cocoa odor.

Occurrence

Reported found in Burley and Virginia tobacco, cooked beef, Swiss cheese, roasted barley, cocoa products, coffee, meat, peanuts, filberts, pecans, popcorn, rum and whiskey, soy products, cooked potato, fried pork, beer, corn, corn tortillas, malt and cooked shrimps.

Uses

2-Ethyl-3,(5 or 6)-dimethylpyrazine is a component of the alarm pheromone of fire ant, Solenopsis invicta. 2-Ethyl-3,(5 or 6)-dimethylpyrazine has shown to attract the phyorid fyl, Pseudacteon tricuspis.

Definition

ChEBI: 2-Ethyl-3,5-dimethylpyrazine is a member of pyrazines.

Preparation

The 2-ethyl-3,5-dimethylpyrazine is obtained by alkylation of dimethyl-2, 6-pyrazine; the 2,5-dimethyl-3-ethylpyrazine is obtained by alkylation of 2,5-dimethylpyrazine with ethyllithium. A mixture of the two can be obtained by condensation of 2,3-pentanedione with propylenediamine. A mixture of the two is obtained from the side chain alkylation of trimethylpyrazine.

Aroma threshold values

Detection: 15 to 43 ppm in water. Aroma characteristics at 1.0%: peanut nutty, caramel, coffee, musty cocoa, popcorn, pyridine, graham sweet with roasted undertones

Taste threshold values

Taste characteristics at 5 ppm: peanut, nut skin, brown, roasted hazelnut with coffee and chocolate nuances.

Biological Activity

Taste at 5 ppm

2-Ethyl-3,5-dimethylpyrazine Preparation Products And Raw materials

Raw materials

Ammonium phosphate dibasic Trimethyl-pyrazine 2,3-Pentanedione

Preparation Products

2-Ethyl-3,5-dimethylpyrazine Suppliers

Global( 126)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16513	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21590	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Longyan Tianhua Biological Technology Co., Ltd	0086 18039857276 18039857276		CHINA	2783	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58

Supplier	Advantage
Hebei Zhuanglai Chemical Trading Co Ltd	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Xiamen AmoyChem Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
Longyan Tianhua Biological Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from 2-Ethyl-3,5-dimethylpyrazine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-17	2-Ethyl-3,5-dimethylpyrazine 27043-05-6	US $2.20-8.80 / kg	1kg	99%min	1000kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2025-12-01	2-Ethyl-3,5-dimethylpyrazine 27043-05-6	US $0.00 / kg	1kg	98%	1000kgs	Shaanxi Dideu New Materials Co. Ltd
2025-05-23	2-Ethyl-3,5-dimethylpyrazine 27043-05-6	US $60.00 / kg	1kg	99%	20 tons	Hebei Zhuanglai Chemical Trading Co Ltd

2-Ethyl-3,5-dimethylpyrazine
27043-05-6
US $2.20-8.80 / kg
99%min
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

2-Ethyl-3,5-dimethylpyrazine
27043-05-6
US $0.00 / kg
98%
Shaanxi Dideu New Materials Co. Ltd

2-Ethyl-3,5-dimethylpyrazine
27043-05-6
US $60.00 / kg
99%
Hebei Zhuanglai Chemical Trading Co Ltd

2-Ethyl-3,5-dimethylpyrazine Spectrum

2-Ethyl-3,5-dimethylpyrazine(27043-05-6)¹HNMR 2-Ethyl-3,5-dimethylpyrazine(27043-05-6)FT-IR 2-Ethyl-3,5-dimethylpyrazine(27043-05-6)IR

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Pyrazine Diethyl ether 3,5-DIMETHYL-2-ETHYLPYRAZINE-D6

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FEMA NUMBER 3149 FEMA 3149 DIMETHYLETHYLPYRAZINE 2,6-DIMETHYL-3-ETHYLPYRAZINE 2-ETHYL-3,5(6)-DIMETHYLPYRAZINE 2-ETHYL-3,5-DIMETHYLPYRAZINE 2-ETHYL-3,5-DIMETHYLPYRAZINE AND 2-ETHYL-3,6-DIMETHYLPYRAZINE 2-ETHYL-3,5(OR 6)-DIMETHYLPYRAZINE 2-ETHYL-3,5(3,6)-DIMETHYLPYRAZINE MIXTURE 3-ETHYL-2,5-DIMETHYLPYRAZINE AND 3-ETHYL-2,6-DIMETHYLPYRAZINE 3-ethyl-3,6-dimethyl-2H-pyrazine 2-ethyl-3,?-dimethyl-pyrazin 2-Ethyl-3，5(or 6)-dimethyrlpyrazine 2-Ethyl-3,(5/6)-dimethylpyrazine, Isomer mixture 2-Ethyl-3,5-diMethyl 2-Ethyl-3,5(6)-dimethylpyrazine, mixture of isomers 3-ethyl-3,6-dimethyl-Pyrazine 2-ethyl-3,-dimethylpyrazine 2-Ethyl-3,5(6)-dimethylpyrazine, 99.5+% Pyrazine, 2-ethyl-3,?-dimethyl- 2-Ethyl-3,5-dimethylpyrazine (contains 2-Ethyl-3,6-dimethylpyrazine) 2-ethyl-3-dimethylpyrazine USP/EP/BP discount 2-Ethyl-3,5-dimethylpyrazine 2-Ethyl-3,5-dimethylpyrazine (contains 2-Ethyl-3,6-dimethylpyrazine), ≥95% 27043-05-6 C8N12N2 C8H12N2