Thiomorpholine-1,1-dioxide
- CAS No.
- 39093-93-1
- Chemical Name:
- Thiomorpholine-1,1-dioxide
- Synonyms
- THIOMORPHOLINE 1,1-DIOXIDE;1,1-DIOXOTHIOMORPHOLINE;DK771;DKSI157;EOS-62289;TIMTEC-BB SBB010267;THIOMORPHOLINE DIOXIDE;Thiomorpholine-1,1-oxide;1,1-DioxidothioMorpholine;ThioMorpholine-1,1-dioxid
- CBNumber:
- CB7140484
- Molecular Formula:
- C4H9NO2S
- Molecular Weight:
- 135.18
- MDL Number:
- MFCD05861623
- MOL File:
- 39093-93-1.mol
- MSDS File:
- SDS
| Melting point | 0°C |
|---|---|
| Boiling point | 0°C |
| Density | 1.239±0.06 g/cm3(Predicted) |
| Flash point | 0°C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 6.48±0.20(Predicted) |
| color | White to Off-White |
| InChI | InChI=1S/C4H9NO2S/c6-8(7)3-1-5-2-4-8/h5H,1-4H2 |
| InChIKey | NDOVLWQBFFJETK-UHFFFAOYSA-N |
| SMILES | N1CCS(=O)(=O)CC1 |
| CAS DataBase Reference | 39093-93-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| Hazard Codes | Xi | |||||||||
| HS Code | 2934999090 | |||||||||
| NFPA 704 |
|
Thiomorpholine-1,1-dioxide price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | T2193 | Thiomorpholine 1,1-Dioxide >98.0%(GC)(T) | 39093-93-1 | 5g | $170 | 2025-07-31 | Buy |
| TCI Chemical | T2193 | Thiomorpholine 1,1-Dioxide >98.0%(GC)(T) | 39093-93-1 | 25g | $523 | 2025-07-31 | Buy |
| TRC | T344568 | Thiomorpholine 1,1-Dioxide | 39093-93-1 | 50mg | $55 | 2021-12-16 | Buy |
| Usbiological | 291067 | Thiomorpholine 1,1-Dioxide | 39093-93-1 | 1g | $396 | 2021-12-16 | Buy |
| TRC | T344568 | Thiomorpholine 1,1-Dioxide | 39093-93-1 | 10mg | $45 | 2021-12-16 | Buy |
Thiomorpholine-1,1-dioxide Chemical Properties,Uses,Production
Chemical Properties
light yellow solid
Uses
Thiomorpholine 1,1-Dioxide is a useful building block, used in the synthetic preparation of antibacterial biaryloxazolidinone analogues, and isothiazolo-pyridine derivatives for use as cyclin G-associated kinase inhibitors and antiviral agents.
Synthesis
To a solution of tert-butylthiomorpholine-4-carboxylate (5.8 g, 0.024 mol) in dichloromethane (50 ml) was added trifluoroacetic acid (70 ml), and the resulting mixture was stirred at 25°C. 5 hours until TLC showed the reaction was complete. Concentrate under reduced pressure to obtain a mixture. Water (30 mL) was added to the mixture, the mixture was basified to pH=8.0 with aqueous ammonia solution, and the mixture was extracted three times with dichloromethane (50 mLx3). The organic extracts were combined and washed with water and brine. The organic extract was dried over anhydrous magnesium sulfate and filtered, and the filtrate was concentrated under reduced pressure to obtain Thiomorpholine 1,1-dioxide.
References
[1] European Journal of Medicinal Chemistry, 2018, vol. 158, p. 247 - 258
[2] Patent: US2006/100426, 2006, A1. Location in patent: Page/Page column 17
[3] Patent: US2006/135764, 2006, A1. Location in patent: Page/Page column 21
[4] Patent: US2006/100236, 2006, A1. Location in patent: Page/Page column 19
[5] Patent: US2006/199839, 2006, A1. Location in patent: Page/Page column 21
Thiomorpholine-1,1-dioxide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taizhou Creating Bio-pharm co., ltd. | 0576-88827176; +8613586099526 | post@creatingbiopharm.com | China | 219 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20190 | 58 |
| Shaanxi Xianhe Biotech Co., Ltd | +86-17709210191; +8617709210191 | Jerry@xhobio.com | China | 883 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 12930 | 58 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 988 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
View Lastest Price from Thiomorpholine-1,1-dioxide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-12 | Thiomorpholine-1,1-dioxide
39093-93-1
|
US $0.00 / kg | 1kg | 0.99 | 1000kg | Shaanxi Xianhe Biotech Co., Ltd | |
 |
2025-04-04 | Thiomorpholine-1,1-dioxide
39093-93-1
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
|
 |
2025-01-03 | Thiomorpholine-1,1-dioxide
39093-93-1
|
US $0.00-0.00 / KG | 1g | 99% | 2000tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Thiomorpholine-1,1-dioxide
39093-93-1
- US $0.00 / kg
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
-
- Thiomorpholine-1,1-dioxide
39093-93-1
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- Thiomorpholine-1,1-dioxide
39093-93-1
- US $0.00-0.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
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