Thiomorpholine-1,1-dioxide
- CAS No.
- 39093-93-1
- Chemical Name:
- Thiomorpholine-1,1-dioxide
- Synonyms
- THIOMORPHOLINE 1,1-DIOXIDE;THIOMORPHOLINE DIOXIDE;1,1-DIOXOTHIOMORPHOLINE;DK771;DKSI157;EOS-62289;TIMTEC-BB SBB010267;Thiomorpholine-1,1-oxide;ThioMorpholine-1,1-dioxid;1,1-DioxidothioMorpholine
- CBNumber:
- CB7140484
- Molecular Formula:
- C4H9NO2S
- Molecular Weight:
- 135.18
- MDL Number:
- MFCD05861623
- MOL File:
- 39093-93-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 0°C |
|---|---|
| Boiling point | 0°C |
| Density | 1.239±0.06 g/cm3(Predicted) |
| Flash point | 0°C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 6.48±0.20(Predicted) |
| color | White to Off-White |
| InChI | InChI=1S/C4H9NO2S/c6-8(7)3-1-5-2-4-8/h5H,1-4H2 |
| InChIKey | NDOVLWQBFFJETK-UHFFFAOYSA-N |
| SMILES | N1CCS(=O)(=O)CC1 |
| CAS DataBase Reference | 39093-93-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| Hazard Codes | Xi | |||||||||
| HS Code | 2934999090 | |||||||||
| NFPA 704 |
|
Thiomorpholine-1,1-dioxide price More Price(71)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | T2193 | Thiomorpholine 1,1-Dioxide >98.0%(GC)(T) | 39093-93-1 | 5g | $135 | 2026-04-30 | Buy |
| TCI Chemical | T2193 | Thiomorpholine 1,1-Dioxide >98.0%(GC)(T) | 39093-93-1 | 25g | $411 | 2026-04-30 | Buy |
| Usbiological | 291067 | Thiomorpholine-1,1-dioxide Asreported | 39093-93-1 | 1g | $396 | 2026-06-03 | Buy |
| Usbiological | 291067 | Thiomorpholine-1,1-dioxide Asreported | 39093-93-1 | 2g | $551 | 2026-06-03 | Buy |
| Usbiological | 291067 | Thiomorpholine-1,1-dioxide Asreported | 39093-93-1 | 5g | $798 | 2026-06-03 | Buy |
Thiomorpholine-1,1-dioxide Chemical Properties,Uses,Production
Chemical Properties
light yellow solid
Uses
Thiomorpholine 1,1-Dioxide is a useful building block, used in the synthetic preparation of antibacterial biaryloxazolidinone analogues, and isothiazolo-pyridine derivatives for use as cyclin G-associated kinase inhibitors and antiviral agents.
Synthesis
To a solution of tert-butylthiomorpholine-4-carboxylate (5.8 g, 0.024 mol) in dichloromethane (50 ml) was added trifluoroacetic acid (70 ml), and the resulting mixture was stirred at 25°C. 5 hours until TLC showed the reaction was complete. Concentrate under reduced pressure to obtain a mixture. Water (30 mL) was added to the mixture, the mixture was basified to pH=8.0 with aqueous ammonia solution, and the mixture was extracted three times with dichloromethane (50 mLx3). The organic extracts were combined and washed with water and brine. The organic extract was dried over anhydrous magnesium sulfate and filtered, and the filtrate was concentrated under reduced pressure to obtain Thiomorpholine 1,1-dioxide.
References
[1] European Journal of Medicinal Chemistry, 2018, vol. 158, p. 247 - 258
[2] Patent: US2006/100426, 2006, A1. Location in patent: Page/Page column 17
[3] Patent: US2006/135764, 2006, A1. Location in patent: Page/Page column 21
[4] Patent: US2006/100236, 2006, A1. Location in patent: Page/Page column 19
[5] Patent: US2006/199839, 2006, A1. Location in patent: Page/Page column 21
Thiomorpholine-1,1-dioxide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Juntai Pharmaceutical Co., Ltd | 18963498209 18963498209 | juntai@h2opharm.com | China | 289 | 58 |
| Suzhou Highfine Biotech Co., Ltd | 0512-69209928 18796809688 | zhouyingxiang@highfine.com | China | 1846 | 58 |
| Smilepep (Hangzhou) Pharmatech Co.,Ltd. | 13857139193 | sales@smilepep.com | China | 183 | 58 |
| Qingdao Dexin Chemical Co. LTD | 18560810705 | 354907727@qq.com | China | 299 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
View Lastest Price from Thiomorpholine-1,1-dioxide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | Thiomorpholine-1,1-dioxide
39093-93-1
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-25 | Thiomorpholine-1,1-dioxide
39093-93-1
|
1kg | 0.99 | 1000kg | Shaanxi Xianhe Biotech Co., Ltd | ||
 |
2026-02-02 | Thiomorpholine-1,1-dioxide
39093-93-1
|
1g | 99% | 2000tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Thiomorpholine-1,1-dioxide
39093-93-1
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- Thiomorpholine-1,1-dioxide
39093-93-1
- $0.00
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
-
- Thiomorpholine-1,1-dioxide
39093-93-1
- 99%
- Shaanxi Dideu Medichem Co. Ltd
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