Neuraminidase-IN-18
- CAS No.
- 2935407-32-0
- Chemical Name:
- Neuraminidase-IN-18
- Synonyms
- Neuraminidase-IN-18;Acetamide, N-[(4-fluorophenyl)methyl]-2-[[5-[(2-naphthalenyloxy)methyl]-1,3,4-oxadiazol-2-yl]thio]-
- CBNumber:
- CB714282602
- Molecular Formula:
- C22H18FN3O3S
- Molecular Weight:
- 423.46
- MDL Number:
- MOL File:
- 2935407-32-0.mol
Neuraminidase-IN-18 Chemical Properties, Uses, Production
Uses
Neuraminidase-IN-18 (compound N5) is a novel polyheterocyclic neuraminidase (NA) inhibitor. Neuraminidase-IN-18 shows potency in inhibition of H5N1 NA with an IC50 of 0.14μM and 0.27μM against the wild-type H5N1 NA and H5N1-H274Y mutant NA, respectively. Neuraminidase-IN-18 inhibits influenza virus replication by binding to NAs in cell level[1].
References
[1] Lin Lin Shang, et al. Discovery of novel polyheterocyclic neuraminidase inhibitors with 1,3,4-oxadiazole thioetheramide as core backbone. European Journal of Medicinal Chemistry, Available online 12 March 2024, 116305.
Neuraminidase-IN-18 Preparation Products And Raw materials
Raw materials
Preparation Products
Neuraminidase-IN-18 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
