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3-(2-Thienyl)-1-propanol

CAS No.
19498-72-7
Chemical Name:
3-(2-Thienyl)-1-propanol
Synonyms
3-(Thiophen-2-yl);2-Thiophenepropanol;3-(2-Thienyl)-1-propanol;3-(thiophen-2-yl)propan-1-ol
CBNumber:
CB71459624
Molecular Formula:
C7H10OS
Molecular Weight:
142.22
MDL Number:
MFCD09927267
MOL File:
19498-72-7.mol
MSDS File:
SDS
Last updated:2026-05-28 02:50:35

3-(2-Thienyl)-1-propanol Properties

Boiling point 240℃
Density 1.131
Flash point 99℃
storage temp. 2-8°C(protect from light)
pka 15.03±0.10(Predicted)
Appearance Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
HS Code  2934999090

3-(2-Thienyl)-1-propanol price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth UAA49872 3-(thiophen-2-yl)propan-1-ol 19498-72-7 5g $472 2026-06-05 Buy
Apolloscientific OR953826 3-(2-Thienyl)-1-propanol >95% 19498-72-7 100mg $24 2026-06-04 Buy
Apolloscientific OR953826 3-(2-Thienyl)-1-propanol >95% 19498-72-7 250mg $39 2026-06-04 Buy
Apolloscientific OR953826 3-(2-Thienyl)-1-propanol >95% 19498-72-7 1g $74 2026-06-04 Buy
Apolloscientific OR953826 3-(2-Thienyl)-1-propanol >95% 19498-72-7 5g $202 2026-06-04 Buy
Product number Packaging Price Buy
UAA49872 5g $472 Buy
OR953826 100mg $24 Buy
OR953826 250mg $39 Buy
OR953826 1g $74 Buy
OR953826 5g $202 Buy

3-(2-Thienyl)-1-propanol Chemical Properties,Uses,Production

Synthesis Reference(s)

The Journal of Organic Chemistry, 36, p. 2236, 1971 DOI: 10.1021/jo00815a008

Synthesis

3-(2-THIENYL)PROPIONIC ACID

5928-51-8

3-(2-Thienyl)-1-propanol

19498-72-7

Step 1: Borane methyl sulfide complex (6.4 mL, 12.8 mmol) was slowly added to a solution of 3-(2-thienyl)propionic acid (1.0 g, 6.4 mmol) in tetrahydrofuran (THF, 18 mL), keeping the reaction temperature at 0 °C. The reaction mixture was stirred continuously at 0 °C for 2 h, and then brought to room temperature and continued stirring for 3 h. The reaction mixture was then cooled to room temperature. Upon completion of the reaction, the mixture was cooled to 0 °C and saturated potassium carbonate solution (5 mL) was slowly added to quench the reaction. The aqueous layer was separated and the organic phase was extracted with ethyl acetate (2 x 15 mL) and ether (2 x 15 mL), respectively. All organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated to dryness under reduced pressure to afford the target product 3-(2-thienyl)-1-propanol as a colorless oil (1.0 g, 100% yield). The product was characterized by 1H NMR (CDCl3, 400 MHz): δ 7.18-7.17 (m, 1H), 6.99-6.96 (m, 1H), 6.87-6.86 (m, 1H), 3.79-3.74 (m, 2H), 3.0 (t, J = 7.6 Hz, 2H), 2.4-1.97 (m, 2H).

References

[1] Patent: WO2011/61214, 2011, A1. Location in patent: Page/Page column 87-88
[2] Patent: WO2008/79382, 2008, A1. Location in patent: Page/Page column 128
[3] Journal of the American Chemical Society, 2015, vol. 137, # 32, p. 10100 - 10103
[4] Patent: US6218538, 2001, B1

3-(2-Thienyl)-1-propanol Preparation Products And Raw materials

Global( 45)Suppliers
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View Lastest Price from 3-(2-Thienyl)-1-propanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-(2-Thienyl)-1-propanol pictures 2020-01-15 3-(2-Thienyl)-1-propanol
19498-72-7
$1.00 1KG 99.0% 100kg Career Henan Chemical Co

3-(2-Thienyl)-1-propanol Spectrum

3-(2-Thienyl)-1-propanol 3-(thiophen-2-yl)propan-1-ol 2-Thiophenepropanol 3-(Thiophen-2-yl) 19498-72-7 Alcohols and Derivatives Heterocycles