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FMOC-D-2-THIENYLALANINE

FMOC-D-2-THIENYLALANINE structure

CAS No.: 201532-42-5

Chemical Name:: FMOC-D-2-THIENYLALANINE

Synonyms: FMOC-D-THI-OH;(R)-N-FMOC-2-THIENYLALANINE;Fmoc-β-(2-thienyl)-D-alanine;FMOC-D-THA;Fmoc-D-2-THI;Fmoc-D-2-Thi-OH;RARECHEM BK PT 0214;FMOC-D-THIENYLALANINE;FMOC-D-2-THIENYLALANINE;FMOC-D-ALA(2-THIENYL)-OH

CBNumber:: CB6438836

Molecular Formula:: C22H19NO4S

Molecular Weight:: 393.46

MDL Number:: MFCD00065677

MOL File:: 201532-42-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:30:43

Product description	Number	Pack Size	Price
Fmoc-D-Thi-OH Novabiochem?	8.52238	5G	$736
Fmoc-D-2-thienylalanine Aldrich^CPR	CDS003855	250 mg	$73.1
Fmoc-D-2-thienylalanine AldrichCPR	CDS003855	250mg	$70.9
Fmoc-beta-(2-thienyl)-D-alanine Asreported	276942	1g	$340
Fmoc-beta-(2-thienyl)-D-alanine Asreported	276942	2g	$466
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FMOC-D-2-THIENYLALANINE Properties

Melting point	169 °C
Boiling point	623.4±55.0 °C(Predicted)
Density	1.343±0.06 g/cm3 (20 ºC 760 Torr)
refractive index	1.5060 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
pka	3.59±0.10(Predicted)
form	solid
color	White to off-white
Major Application	peptide synthesis
InChI	InChI=1/C22H19NO4S/c24-21(25)20(12-14-6-5-11-28-14)23-22(26)27-13-19-17-9-3-1-7-15(17)16-8-2-4-10-18(16)19/h1-11,19-20H,12-13H2,(H,23,26)(H,24,25)/t20-/s3
InChIKey	PXBMQFMUHRNKTG-XKGZFIRZNA-N
SMILES	C(C1C2=CC=CC=C2C2=CC=CC=C12)OC(=O)N[C@@H](C(=O)O)CC1SC=CC=1 \|&1:18,r\|
CAS DataBase Reference	201532-42-5(CAS DataBase Reference)
UNSPSC Code	12352209
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Hazard Codes	Xi
Safety Statements	24/25
WGK Germany	3
HazardClass	IRRITANT
HS Code	29309090
Storage Class	11 - Combustible Solids

FMOC-D-2-THIENYLALANINE price More Price(84)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	8.52238	Fmoc-D-Thi-OH Novabiochem?	201532-42-5	5G	$736	2026-04-30	Buy
Sigma-Aldrich	CDS003855	Fmoc-D-2-thienylalanine Aldrich^CPR		250 mg	$73.1	2025-07-31	Buy
Sigma-Aldrich	CDS003855	Fmoc-D-2-thienylalanine AldrichCPR	201532-42-5	250mg	$70.9	2024-03-01	Buy
Usbiological	276942	Fmoc-beta-(2-thienyl)-D-alanine Asreported	201532-42-5	1g	$340	2026-06-03	Buy
Usbiological	276942	Fmoc-beta-(2-thienyl)-D-alanine Asreported	201532-42-5	2g	$466	2026-06-03	Buy

Product number	Packaging	Price	Buy
8.52238	5G	$736	Buy
CDS003855	250 mg	$73.1	Buy
CDS003855	250mg	$70.9	Buy
276942	1g	$340	Buy
276942	2g	$466	Buy

FMOC-D-2-THIENYLALANINE Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

Synthesis

Propanedioic acid, 2-thienyl-, diethyl ester

88798-28-1

N-(9-Fluorenylmethoxycarbonyloxy)succinimide

82911-69-1

201532-42-5

2.3 Diethyl 2-thienylmalonate was used as the starting material, and the saponification reaction was first carried out with 2.3 equivalents of aqueous sodium hydroxide. Subsequently, L-acylase, 9-fluorenylmethyl-N-succinimidyl carbonate (Fmoc-OSu) and acetone were added, and the pH of the reaction system was adjusted to 8-9 with aqueous sodium carbonate.After completion of the reaction, Fmoc-Thi-OH was isolated (stored separately), and the mother liquor was frozen and stored.2.4 About 2 L of the above mother liquor was transferred to a 5 L three-necked flask, and 1 L of a mixture of hydrochloric acid and methanol mixture. The reaction mixture was heated to reflux for 60 hours. The reaction was monitored by nuclear magnetic resonance (NMR) and thin layer chromatography (TLC). When the reaction was essentially complete, the Fmoc-OSu solid was removed by filtration and the reaction process continued to be followed by TLC. After the reaction was complete, the reaction system was washed four times with 500 mL of a solvent mixture of ethyl acetate and petroleum ether. Subsequently, the reaction system was acidified with hydrochloric acid to a pH of about 1. Cooling and stirring resulted in 48 g of brown crystalline product.

References

[1] Patent: CN106565665, 2017, A. Location in patent: Paragraph 0016-0018; 0021-0023; 0026-0027; 0030-0031; 0038

FMOC-D-2-THIENYLALANINE Preparation Products And Raw materials

Raw materials

Propanedioic acid, 2-thienyl-, diethyl ester Fmoc-OSu Water Methanol Sodium hydroxide

Hydrochloric acid

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Preparation Products

FMOC-D-2-THIENYLALANINE Suppliers

Global( 133)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16512	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
GenicBio Limited	+86-21-37621270	service@genicbio.com	CHINA	991	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58
GL Biochem(Binhai) Ltd.	+86-021-61263370 +8615301650015	wuqiuyan@glschina.com	China	2975	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9996	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58

Supplier	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60
GenicBio Limited	58
career henan chemical co	58
GL Biochem (Shanghai) Ltd.	58
GL Biochem(Binhai) Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58
Shaanxi Dideu Medichem Co. Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Nextpeptide Inc	58

View Lastest Price from FMOC-D-2-THIENYLALANINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-17	Fmoc-β-(2-thienyl)-D-alanine 201532-42-5	$3.00-9.00		99%		ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
	2019-07-06	FMOC-D-2-THIENYLALANINE 201532-42-5	$1.00	1KG	99%	20kg	Career Henan Chemical Co

Fmoc-β-(2-thienyl)-D-alanine
201532-42-5
$3.00-9.00
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

FMOC-D-2-THIENYLALANINE
201532-42-5
$1.00
99%
Career Henan Chemical Co

201532-42-5(FMOC-D-2-THIENYLALANINE)Related Search:

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3-(2-THIENYL)PROPIONIC ACID BETA-(2-THIENYL)-DL-ALANINE (S)-N-FMOC-2-Thienylalanine 3-(2-Thienyl)-1-propanol D-2-THIENYLALANINE

FMOC-3-(2-THIENYL)-DL-ALANINE FMOC-D-3-THIENYLALANINE FMOC-L-3-THIENYLALANINE FMOC-DL-3-THIENYLALANINE 1-METHYL-2-THIOPHEN-2-YL-ETHYLAMINE

FMOC-D-ALA-ALDEHYDE FMOC-D-2-THIENYLALANINE METHYL-(2-THIOPHEN-2-YL-ETHYL)-AMINE

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FMOC-3-(2-THIENYL)-D-ALANINE FMOC-D-2-THIENYLALANINE FMOC-D-ALA(2-THIENYL)-OH FMOC-D-THA FMOC-D-THIENYLALANINE Fmoc-D-2-Thi-OH Fmoc-D-3-(2-Thienyl)-alanine Fmoc-D-3-(2-Thienyl)-L-alanine (R)-N-fmoc-2-Thienylalanine(e.e.) 3-Thien-2-yl-D-alanine, N-FMOC protected (R)-N-Fmoc-2-thienylalanine, 95%, ee:98% (R)-N-FMOC-2-Thienylalanine, 98% ee (αR)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-thiophenepropanoic acid Fmoc-D-2-THI (2R)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-thiophen-2-ylpropanoate (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(thiophen-2-yl)propanoic acid (R)-N-FMOC-2-Thienylalanine,95%,98% ee FMoc-b-(2-thienyl)-D-Ala-OH (R)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-3-(thiophen-2-yl)propanoic acid Fmoc-β-(2-thienyl)-D-alanine≥ 98% (HPLC) Fmoc-D-Thi-OH Novabiochem N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-BETA-(2-THIENYL)-D-ALANINE N-(9-FLUORENYLMETHOXYCARBONYL)-2-THIENYL-D-ALANINE N-ALPHA-FMOC-BETA-THIENYL-D-ALANINE RARECHEM BK PT 0214 FMOC-3-D-ALA(2-THIENYL)-OH FMOC-BETA-(2-THIENYL)-D-ALANINE FMOC-BETA-(2-THIENYL)-D-ALA-OH FMOC-D-THI-OH (FMOC-D-3-(2-THIENYL)-ALANINE) (9H-Fluoren-9-yl)MethOxy]Carbonyl β-(2-thienyl)-D-Alanine N-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-(thien-2-yl)-D-alanine, (2R)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(thien-2-yl)propanoic acid FMoc-β-(2-thienyl)-D-alanine, ee: 98% 2-Thiophenepropanoic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (αR)- FMOC-D-2-THIENYLALANINE USP/EP/BP (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-thiophen-2-ylpropanoate Fmoc-3-(2-thienyl)-D-Ala-OH N-(((9H-fluoren-9-yl)methoxy)carbonyl)-N-(thiophen-2-yl)-D-alanine (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(thiophen-2-yl)propanoic acid - [F90760] (R)-N-FMOC-2-THIENYLALANINE FMOC-D-THI-OH Fmoc-β-(2-thienyl)-D-alanine 201532-42-5 C22HNO4S C22H18NO4S Phenylalanine analogs and other aromatic alpha amino acids Amino Acid Derivatives a-amino Amino Acids