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ChemicalBook >> CAS DataBase List >>(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Structure
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol structure
CAS No.
289893-25-0
Chemical Name:
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol
Synonyms
arimoclomol;Pefcalcitol;Amrioclomol;(2R-)Arimoclomol;BRX-220 free base;(2R-)Arimoclomol NEW;Arimoclomol, 10 mM in DMSO;(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol;3-Pyridinecarboximidoyl chloride, N-[(2R)-2-hydroxy-3-(1-piperidinyl)propoxy]-, 1-oxide;aggregation,Heat shock proteins,HSP,co-inducer,system,BRX220,motor,Arimoclomol,inhibit,ubiquitin,BRX 220,neurons,misfolded,proteasome,BRX-220,protein,assemblies,clearance,Inhibitor
CBNumber:
CB71480024
Molecular Formula:
C14H20ClN3O3
Molecular Weight:
313.78
MDL Number:
MFCD16660939
MOL File:
289893-25-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:22:57
Product description Number Pack Size Price
Arimoclomol ≥98% 37368 1mg $124
Arimoclomol ≥98% 37368 5mg $460
Arimoclomol ≥98% 37368 10mg $797
(2R-)Arimoclomol FA30834 25mg $317.75
(2R-)Arimoclomol FA30834 50mg $544
Request For Quotation

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Properties

Melting point 93 - 95o C
Boiling point 539.2±60.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 14.03±0.20(Predicted)
color White to Off-White
Stability Hygroscopic
FDA UNII EUT3557RT5

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)
GHS02
Signal word  Danger
Hazard statements  H261
Precautionary statements  P223-P231+P232-P280-P335+P334-P370+P378-P402+P404-P501
NFPA 704
0
0 2

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 37368 Arimoclomol ≥98% 289893-25-0 1mg $124 2026-04-30 Buy
Cayman Chemical 37368 Arimoclomol ≥98% 289893-25-0 5mg $460 2026-04-30 Buy
Cayman Chemical 37368 Arimoclomol ≥98% 289893-25-0 10mg $797 2026-04-30 Buy
Biosynth FA30834 (2R-)Arimoclomol 289893-25-0 25mg $317.75 2026-06-04 Buy
Biosynth FA30834 (2R-)Arimoclomol 289893-25-0 50mg $544 2026-06-04 Buy
Product number Packaging Price Buy
37368 1mg $124 Buy
37368 5mg $460 Buy
37368 10mg $797 Buy
FA30834 25mg $317.75 Buy
FA30834 50mg $544 Buy

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Chemical Properties,Uses,Production

Uses

Arimoclomol is a co-inducer of HSP that acts through heat shock factor 1 (HSF1) in cells undergoing cellular stress. Has therapeutic potential in motor neuron degenerative diseases. Potential treatment for liposomal storage disorders, such as Niemann-Pick disease type C.

in vivo

Arimoclomol (BRX-220; 20 mg/kg; orally administered for 5 d) has a protective effect against cholecystokinin-octapeptide (CCK)-induced acute pancreatitis[1].

Animal Model:Male Wistar rats weighing 240 to 270 g[1]
Dosage:20 mg/kg
Administration:Administered intragastrically, for 5 days
Result:Had a protective effect against CCK-induced acute pancreatitis.

IC 50

HSP

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Suppliers

Global( 49)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21531 55
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
RongNa Biotechnology Co.,Ltd 		+86-86-13583358881 +8618560316533 Brad@rongnabiotech.com China 3371 58
BOC Sciences 		16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 38999 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+86-18327326525 masar@topule.com China 8433 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +86-15965530500 nickzhang@hangyubiotech.com China 9935 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		+86-18341751992 +86-15382112998 757984502@qq.com China 890 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 +86-15355479329 market18@leapchem.com China 43303 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+86-0086-13720134139 orders@jknbiochem.com China 5215 58
Supplier Advantage
Henan Tianfu Chemical Co.,Ltd. 		55
TargetMol Chemicals Inc. 		58
RongNa Biotechnology Co.,Ltd 		58
BOC Sciences 		58
TargetMol Chemicals Inc. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Zibo Hangyu Biotechnology Development Co., Ltd 		58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58

View Lastest Price from (2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol pictures 2026-08-14 (2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol
289893-25-0
 0.99 RongNa Biotechnology Co.,Ltd
Arimoclomol pictures 2026-04-22 Arimoclomol
289893-25-0
 $54.00-148.00 99.81% 10g TargetMol Chemicals Inc.
Arimoclomol pictures 2026-04-22 Arimoclomol
289893-25-0
 $54.00-148.00 99.81% 10g TargetMol Chemicals Inc.
  • Arimoclomol pictures
  • Arimoclomol
    289893-25-0
  • $54.00-148.00
  • 99.81%
  • TargetMol Chemicals Inc.
  • Arimoclomol pictures
  • Arimoclomol
    289893-25-0
  • $54.00-148.00
  • 99.81%
  • TargetMol Chemicals Inc.

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Spectrum

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol(289893-25-0)1HNMR

289893-25-0((2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol)Related Search:

Aprepitant Troxerutin MTP 131 acetate GYPENOSIDE-XVII BACOPASIDE I(SH)
Geniposide

1of2

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Amrioclomol (2R-)Arimoclomol NEW BRX-220 free base 3-Pyridinecarboximidoyl chloride, N-[(2R)-2-hydroxy-3-(1-piperidinyl)propoxy]-, 1-oxide aggregation,Heat shock proteins,HSP,co-inducer,system,BRX220,motor,Arimoclomol,inhibit,ubiquitin,BRX 220,neurons,misfolded,proteasome,BRX-220,protein,assemblies,clearance,Inhibitor Arimoclomol, 10 mM in DMSO (2R-)Arimoclomol arimoclomol Pefcalcitol 289893-25-0