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PFI-7

PFI-7 structure

CAS No.: 2910938-58-6

Chemical Name:: PFI-7

Synonyms: PFI-7;Acetamide, N-[cis-4-(1H-benzimidazol-2-yl)cyclohexyl]-2-[(1H-indol-2-ylmethyl)amino]-

CBNumber:: CB714907752

Molecular Formula:: C24H27N5O

Molecular Weight:: 401.5

MDL Number:

MOL File:: 2910938-58-6.mol

MSDS File:: SDS

Last updated:2025-05-19 13:47:43

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PFI-7 Properties

Boiling point	757.770±60.00 °C(Press: 760.00 Torr)(predicted)
Density	1.293±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	11.806±0.10(predicted)

PFI-7 Chemical Properties, Uses, Production

Uses

PFI-7 is a probe, which binds to human GID4 (KD is 79 nM), and antagonizes the binding of Pro/N-degrons. PFI-7 can be utilized in C-terminal to LisH (CTLH) complex research and development of targeted protein degradation[1].

References

[1] Owens DDG, et al., A chemical probe to modulate human GID4 Pro/N-degron interactions. Nat Chem Biol. 2024 May 21. DOI:10.1038/s41589-024-01618-0

PFI-7 Preparation Products And Raw materials

Raw materials

Preparation Products

PFI-7 Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol	400-821-0310 15002144251	xuexiang.shao@tsbiochem.com	China	29128	58

Supplier	Advantage
TargetMol	58

2910938-58-6 (PFI-7) Related Search:

UBA1 Protein, Human (sf9, His-GST) UBA5 Protein, Human (His) UBE2A Protein, Human (GST-His) WWP2 Protein, Human (sf9, His-GST) AMG 232

BI 907828

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PFI-7 Acetamide, N-[cis-4-(1H-benzimidazol-2-yl)cyclohexyl]-2-[(1H-indol-2-ylmethyl)amino]- 2910938-58-6