5-Methoxy-nicotinic acid
- CAS No.
- 20826-03-3
- Chemical Name:
- 5-Methoxy-nicotinic acid
- Synonyms
- 5-Methoxynicotinic acid;5-methoxypyridine-3-carboxylicaci;3-Methoxypyridine-5-carboxylic acid;3-Methoxy-5-pyridinecarboxylic acid;3-Pyridinecarboxylic acid, 5-methoxy-;5-Methoxypyridine-3-carboxylic acid, 3-Carboxy-5-methoxypyridine
- CBNumber:
- CB71502740
- Molecular Formula:
- C7H7NO3
- Molecular Weight:
- 153.14
- MDL Number:
- MFCD01603648
- MOL File:
- 20826-03-3.mol
- MSDS File:
- SDS
| Melting point | 127-131°C |
|---|---|
| Boiling point | 330.9±22.0 °C(Predicted) |
| Density | 1.284±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 2.08±0.10(Predicted) |
| form | solid |
| color | Off-white to light grey |
| InChI | 1S/C7H7NO3/c1-11-6-2-5(7(9)10)3-8-4-6/h2-4H,1H3,(H,9,10) |
| InChIKey | VDZUWTLBWRZRTR-UHFFFAOYSA-N |
| SMILES | COc1cncc(c1)C(O)=O |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| target organs | Respiratory system |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
5-Methoxy-nicotinic acid price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR16421 | 5-Methoxynicotinic acid ≥95% | 20826-03-3 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR16421 | 5-Methoxynicotinic acid ≥95% | 20826-03-3 | 1g | $28 | 2026-06-04 | Buy |
| Synthonix | M45836 | 5-Methoxynicotinic acid 97% | 20826-03-3 | 250mg | $20 | 2026-05-06 | Buy |
| Synthonix | M45836 | 5-Methoxynicotinic acid 97% | 20826-03-3 | 1g | $26 | 2026-05-06 | Buy |
| Synthonix | M45836 | 5-Methoxynicotinic acid 97% | 20826-03-3 | 5g | $70 | 2026-05-06 | Buy |
5-Methoxy-nicotinic acid Chemical Properties, Uses, Production
Synthesis
29681-46-7
20826-03-3
General procedure for the synthesis of 5-methoxynicotinic acid from methyl 5-methoxypyridine-3-carboxylate: 2 M aqueous NaOH solution (3 mL) was added to a mixed solution of THF (4 mL) and methanol (4 mL) containing methyl 5-methoxynicotinate (300 mg, 1.79 mmol). The reaction mixture was stirred at room temperature for 14 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was diluted with distilled water (20 mL) and the pH of the aqueous phase was subsequently adjusted to 6 with 2 M aqueous HCl. The aqueous phase was extracted with dichloromethane (20 mL x 3), the organic phases were combined and washed with saturated saline (10 mL x 2), dried over anhydrous sodium sulfate, and concentrated to give the title compound, 5-methoxynicotinic acid, as a white solid (230 mg, 84% yield).LC-MS analysis Results: retention time 0.36 min; m/z 154.1 [M+H]+.
References
[1] Journal of Medicinal Chemistry, 2000, vol. 43, # 16, p. 3168 - 3185
[2] Patent: WO2016/34673, 2016, A1. Location in patent: Page/Page column 125-126
5-Methoxy-nicotinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Nan Jing Dirise Chemcial Co.,LTD | 025-52161033 15312098939 | 2432674894@qq.com | China | 585 | 64 |
| Nanjing Kaitian Chemical Co., Ltd. | +86 (25) 5860-8846 | kt_chem@126.com | China | 218 | 62 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Nanjing Vital Chemical Co., Ltd. | Please Send Email 18652950785 | chemweiao@163.com | China | 4368 | 65 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
View Latest Price from 5-Methoxy-nicotinic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-13 | 5-METHOXY-NICOTINIC ACID
20826-03-3
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 5-METHOXY-NICOTINIC ACID
20826-03-3
- $1.00
- 99%
- Career Henan Chemical Co
