2-Iodoanisole
- CAS No.
- 529-28-2
- Chemical Name:
- 2-Iodoanisole
- Synonyms
- 1-IODO-2-METHOXYBENZENE;Iodanisol;O-IODOANISOLE;2-IODOANISOLE;o-Anisyl iodide;2-Iodoanisole97%;Anisole, o-iodo-;2-Iodoanisole 97%;2-Iodoanisole,99%;2-Iodoanisole
- CBNumber:
- CB7161179
- Molecular Formula:
- C7H7IO
- Molecular Weight:
- 234.03
- MDL Number:
- MFCD00001039
- MOL File:
- 529-28-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 588.5 °C |
|---|---|
| Boiling point | 125-126 °C19 mm Hg(lit.) |
| Density | 1.799 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >110°C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | alcohol: miscible(lit.) |
| form | Liquid |
| color | Clear yellow |
| Specific Gravity | 1.799 |
| Water Solubility | insoluble |
| Sensitive | Light Sensitive |
| Merck | 14,5028 |
| BRN | 1860243 |
| InChI | 1S/C7H7IO/c1-9-7-5-3-2-4-6(7)8/h2-5H,1H3 |
| InChIKey | DVQWNQBEUKXONL-UHFFFAOYSA-N |
| SMILES | COc1ccccc1I |
| CAS DataBase Reference | 529-28-2(CAS DataBase Reference) |
| FDA UNII | 75Y5532R8O |
| NIST Chemistry Reference | 2-Iodoanisole(529-28-2) |
| EPA Substance Registry System | Benzene, 1-iodo-2-methoxy- (529-28-2) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29093090 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| NFPA 704 |
|
2-Iodoanisole price More Price(66)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 252786 | 2-Iodoanisole 98% | 529-28-2 | 25g | $64.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | 252786 | 2-Iodoanisole 98% | 529-28-2 | 100g | $162 | 2026-04-30 | Buy |
| TCI Chemical | I0382 | 2-Iodoanisole (stabilized with Copper chip) >98.0%(GC) | 529-28-2 | 25g | $58 | 2026-04-30 | Buy |
| TCI Chemical | I0382 | 2-Iodoanisole (stabilized with Copper chip) min.98.0% | 529-28-2 | 100G | $158 | 2026-04-30 | Buy |
| Usbiological | 280921 | 1-Iodo-2-methoxybenzene Asreported | 529-28-2 | 100g | $355 | 2026-06-03 | Buy |
2-Iodoanisole Chemical Properties, Uses, Production
Chemical Properties
Clear yellow liquid
Uses
suzuki reaction
Uses
2-Iodoanisole has been used in palladium/copper-catalyzed synthesis of o-(1-alkynyl)anisoles.
Definition
ChEBI: An organoiodine compound that is iodobenzene substituted by methoxy group at psotion 2.
General Description
2-Iodoanisole participates in palladium catalyzed enantioselective Heck arylation of 2,3-dihydrofuran in the presence of chiral ionic liquids containing L-prolinate and L-lactate anions and non-chiral quaternary ammonium cations.
Synthesis
(1) Prepare 2 moles of 20% NaI aqueous solution A and 2.1 moles of 8-10% sodium hypochlorite aqueous solution B for spare use;
(2) Add 900g of anisole in a 2L four-necked round-bottomed flask equipped with stirring, a temperature display, and two constant-pressure dropping funnels and heat it up to 60-70C with stirring; then, dropwise add the sodium iodide solution and sodium hypochlorite solution simultaneously at the ratio of molar ratio 1:1.05 with stirring;
(3) After dropping and adding, warm it up to 75-80C and get the light yellow reaction solution; cool it down to 75-80C; and cool it down to 80%. Sodium iodide solution and sodium hypochlorite solution;
(3) after dropping, warm up to 75~80 , stirring for 1 hour, to get light yellow reaction solution; cooled to room temperature, static phase splitting; the organic phase washed with water, drying and filtration, to get the anisole solution of 2-iodoanisole, distillation, cooling, curing, to get the white lumpy crystals, i.e., 2-iodoanisole, whose content is 98.5%, yield 93.4% .
2-Iodoanisole Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
View Latest Price from 2-Iodoanisole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-08-06 | 2-Iodoanisole
529-28-2
|
$1.00 | 1KG | 98% | 150KG | Career Henan Chemical Co |
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- 2-Iodoanisole
529-28-2
- $1.00
- 98%
- Career Henan Chemical Co
