Pentafluorobenzyl chloride
- CAS No.
- 653-35-0
- Chemical Name:
- Pentafluorobenzyl chloride
- Synonyms
- PENTAFLUOROBENZYL CHLORIDE;Pentafluorobenzylchloride98%;Pentafluorobenzyl chloride 98%;(chloromethyl)pentafluorobenzene;2,3,4,5,6-PENTAFLUOROBENZYL CHLORIDE;à-chloro-2,3,4,5,6-pentafluorotoluene;2,3,4,5,6-Pentafluorobenzyl chloride 98%;alpha-Chloro-2,3,4,5,6-pentafluorotoluene;1-(Chloromethyl)-2,3,4,5,6-pentafluorobenzene;2,3,4,5,6-Pentafluoro-1-(chloromethyl)benzene
- CBNumber:
- CB1703177
- Molecular Formula:
- C7H2ClF5
- Molecular Weight:
- 216.54
- MDL Number:
- MFCD00040864
- MOL File:
- 653-35-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2,3,4,5,6-Pentafluorobenzyl chloride 98% | PC0238 | 10g | $275 |
| 2,3,4,5,6-Pentafluorobenzyl chloride 98% | PC0238 | 25g | $521 |
| 2,3,4,5,6-Pentafluorobenzyl chloride 98% | PC0238 | 100g | $1539 |
| Pentafluorobenzyl chloride 98% | 1700-6-X9 | 25g | $275 |
| Pentafluorobenzyl chloride 98% | 1700-6-X9 | 100g | $875 |
| More product size | |||
| Boiling point | 72 °C |
|---|---|
| Density | 1.59 |
| refractive index | 1.443 |
| Flash point | 72°C/22mm |
| form | liquid |
| Specific Gravity | 1.59 |
| color | Clear, colourless |
| Water Solubility | Not miscible in water. |
| Sensitive | Lachrymatory |
| BRN | 647807 |
| CAS DataBase Reference | 653-35-0(CAS DataBase Reference) |
| FDA UNII | J3AMF5UR8V |
| NIST Chemistry Reference | Benzene, (chloromethyl)pentafluoro-(653-35-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H312-H314-H318-H332 | |||||||||
| Precautionary statements | P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | 2927 | |||||||||
| Hazard Note | Irritant/Lachrymatory | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 2903998090 | |||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
Pentafluorobenzyl chloride price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC0238 | 2,3,4,5,6-Pentafluorobenzyl chloride 98% | 653-35-0 | 10g | $275 | 2026-06-04 | Buy |
| Apolloscientific | PC0238 | 2,3,4,5,6-Pentafluorobenzyl chloride 98% | 653-35-0 | 25g | $521 | 2026-06-04 | Buy |
| Apolloscientific | PC0238 | 2,3,4,5,6-Pentafluorobenzyl chloride 98% | 653-35-0 | 100g | $1539 | 2026-06-04 | Buy |
| SynQuest Laboratories | 1700-6-X9 | Pentafluorobenzyl chloride 98% | 653-35-0 | 25g | $275 | 2026-05-22 | Buy |
| SynQuest Laboratories | 1700-6-X9 | Pentafluorobenzyl chloride 98% | 653-35-0 | 100g | $875 | 2026-05-22 | Buy |
Pentafluorobenzyl chloride Chemical Properties,Uses,Production
Uses
2,3,4,5,6-Pentafluorobenzyl chloride can be used as a pharmaceutical synthesis intermediate. It can be prepared by reacting hexafluorobenzene with methyllithium and can be used to prepare 2,3,4,5,6-pentafluorobenzyl cyanide.
Synthesis
An ether solution of methyl lithium (70 cc, containing 21 g of methyl lithium) was added to hexafluorobenzene (20 g) in dry ether (20 cc) at a rate sufficient to maintain mild reflux, stirred, and after addition and addition of water (100 cc), stirring was maintained for one hour. The ether layer was dried (MgSO4), filtered, and most of the ether was distilled off through a 6-inch column to separate the residual liquid (17 g), which was passed through a gas chromatograph 100 (column 488 cm x 75 mm, packed with silicone rubber/ diatomaceous earth 1:3, temperature 1000°C, no flow rate 451/hr) to give 2,3,4,5,6-pentafluorotoluene (138 g). Reaction with one molecular equivalent of sulfonyl chloride then halogenates the methyl in the presence of 0005 molecular equivalents of dibenzoyl peroxide The major product is 2,3,4,5,6-pentafluorobenzyl chloride with a boiling point of 88-90°C and a mercury pressure of 69 mm.
Pentafluorobenzyl chloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8737 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20111 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1444 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10817 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14301 | 58 |
View Lastest Price from Pentafluorobenzyl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-13 | Pentafluorobenzyl chloride
653-35-0
|
$5.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
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2026-03-20 | Pentafluorobenzyl chloride
653-35-0
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2025-04-04 | Pentafluorobenzyl chloride
653-35-0
|
1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
-
- Pentafluorobenzyl chloride
653-35-0
- $5.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- Pentafluorobenzyl chloride
653-35-0
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Pentafluorobenzyl chloride
653-35-0
- 98%
- Henan Aochuang Chemical Co.,Ltd.
