ASPOCHALASIN D
- CAS No.
- 71968-02-0
- Chemical Name:
- ASPOCHALASIN D
- Synonyms
- ASPOCHALASIN D;isoaspochalasinC;[3S,13E,17S,18S,19E,(-)]-17,18-Dihydroxy-14-methyl-3-(2-methylpropyl)-10-nor[11]cytochalasa-6,13,19-triene-1,21-dione;1H-Cycloundec(d)isoindole-1,15(2H)-dione, 3,3a,4,6a,9,10,11,12-octahyd ro-11,12-dihydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-, (3S,3aR,4S,6aS ,7E,11R,12S,13E,15aS)-
- CBNumber:
- CB7192029
- Molecular Formula:
- C24H35NO4
- Molecular Weight:
- 401.54
- MDL Number:
- MFCD31380756
- MOL File:
- 71968-02-0.mol
- MSDS File:
- SDS
| Boiling point | 607.6±55.0 °C(Predicted) |
|---|---|
| Density | 1.15±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: soluble |
| form | A solid |
| pka | 13.10±0.70(Predicted) |
| FDA UNII | SE2RF5V7VG |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| HS Code | 29419000 | |||||||||
| NFPA 704 |
|
ASPOCHALASIN D price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 23864 | Aspochalasin D ≥95% | 71968-02-0 | 1mg | $202 | 2026-04-30 | Buy |
| Cayman Chemical | 23864 | Aspochalasin D ≥95% | 71968-02-0 | 5mg | $797 | 2026-04-30 | Buy |
| Biosynth | WCA96802 | Aspochalasin D | 71968-02-0 | 5mg | $1484.95 | 2026-06-05 | Buy |
| Biosynth | WCA96802 | Aspochalasin D | 71968-02-0 | 10mg | $2065.9 | 2026-06-05 | Buy |
| Biosynth | WCA96802 | Aspochalasin D | 71968-02-0 | 25mg | $3873.75 | 2026-06-05 | Buy |
ASPOCHALASIN D Chemical Properties, Uses, Production
Description
Aspochalasin D is a co-metabolite originally isolated from A. microcysticus with aspochalasins A, B, and C, that was initially thought to be inactive. It has antibacterial activity against Gram-positive and Gram-negative bacteria at a concentration of 1 mg/ml. Aspochalasin D is more cytotoxic, via apoptosis, to Ba/F3-V12 cells in an IL-3-free medium than in an IL-3-containing medium (IC50s = 0.49 and 1.9 μg/ml, respectively).
Uses
Aspochalasin D is a co-metabolite originally isolated from A. microcysticus with aspochalasins A, B, and C, that is initially thought to be inactive. It has antibacterial activity against Gram-positive and Gram-negative bacteria at a concentration of 1 mg/ml.2 Aspochalasin D is more cytotoxic, via apoptosis, to Ba/F3-V12 cells in an IL-3-free medium than in an IL-3-containing medium (IC50s=0.49 and 1.9 μg/mL, respectively).
References
[1] Gebhardt, et al. Aspochalamins A-D and aspochalasin Z produced by the endosymbiotic fungus Aspergillus niveus LU 9575 I. Taxonomy, fermentation, isolation and biological activities. J. Antibiot. (Tokyo) 57(11), 707-714 (2004).
ASPOCHALASIN D Preparation Products And Raw materials
Raw materials
Preparation Products
ASPOCHALASIN D Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 | sales@mitachieve.com | China | 8857 | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-61109150 | sales@tcisct.com | China | 29717 | 58 |
| Shanghai Saikerui Biotechnology Co. , Ltd. | 021-58000709 13120558703 | sales@scrbio.com | China | 9873 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Shanghai Weiyite Biotechnology Co., Ltd | 15317051735 | zhaojing@wytsci.com | China | 10000 | 58 |
