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NOMIFENSINE MALEATE SALT

NOMIFENSINE MALEATE SALT Structure
NOMIFENSINE MALEATE SALT structure
CAS No.
32795-47-4
Chemical Name:
NOMIFENSINE MALEATE SALT
Synonyms
merital;hoe984;Alival;meritalam;hostalival;NSC-289114;NOMIFENSINE MALEATE;alival(antidepressant);(±)-Nomifensine maleat;NOMIFENSINE MALEATE SALT
CBNumber:
CB7202667
Molecular Formula:
C16H18N2.C4H4O4
Molecular Weight:
354.4
MDL Number:
MFCD00069320
MOL File:
32795-47-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-04 11:17:55
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NOMIFENSINE MALEATE SALT Properties

Melting point 199-201°
storage temp. Refrigerator, Under Inert Atmosphere
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
color Crystals from EtOH
Water Solubility Water : 2.2 mg/mL (6.21 mM; Need ultrasonic)
InChI 1S/C16H18N2.C4H4O4/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18;5-3(6)1-2-4(7)8/h2-9,14H,10-11,17H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChIKey GEOCVSMCLVIOEV-BTJKTKAUSA-N
SMILES [H]\C(=C(/[H])C(O)=O)C(O)=O.CN1CC(c2ccccc2)c3cccc(N)c3C1
FDA UNII 76S8CUH5MR
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36
RIDADR  3249
WGK Germany  3
RTECS  NX4912800
HazardClass  6.1(b)
PackingGroup  III
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Toxicity LD50 in mice, rats (mg/kg): 400, 430 orally; 90, 72 i.v.; in mice (mg/kg): 410 s.c. (Hoffman, 1973)

NOMIFENSINE MALEATE SALT price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N1530 Nomifensine maleate salt 32795-47-4 100mg $327 2026-04-30 Buy
Usbiological 256012 Nomifensine Asreported 32795-47-4 50mg $360 2026-06-03 Buy
TRC TRC-N635950-5G Nomifensine Maleic Acid Salt 32795-47-4 5g $1860 2026-06-03 Buy
TRC TRC-N635950-50MG Nomifensine Maleic Acid Salt 32795-47-4 50mg $133 2026-06-03 Buy
TRC TRC-N635950-100MG Nomifensine Maleic Acid Salt 32795-47-4 100mg $212 2026-06-03 Buy
Product number Packaging Price Buy
N1530 100mg $327 Buy
256012 50mg $360 Buy
TRC-N635950-5G 5g $1860 Buy
TRC-N635950-50MG 50mg $133 Buy
TRC-N635950-100MG 100mg $212 Buy

NOMIFENSINE MALEATE SALT Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Solid

Originator

Alival,Hoechst,W. Germany ,1976

Uses

Antidepressant;Dopamine uptake inhibitor

Uses

A novel antidepressant distinguished from existing tricyclic and tetracyclic antidepressants by its bicyclic structure.

Uses

Nomifensine maleate salt has been used to study the β-CFT (cocaine analogue) binding using human embryonic kidney 293T cells.

Manufacturing Process

A solution of N-(2-aminobenzyl)-1-phenyl-2-methylaminoethanol-1 was prepared by the reaction of α-bromo-acetophenone and (2nitrobenzyl)methylamine, followed by hydrogenation of the nitro group by means of nickel on diatomaceous earth at room temperature and reduction of the CO group by means of sodium borohydride. The intermediate thus produced was dissolved in 100 ml of methylene chloride and introduced dropwise into 125 ml of sulfuric acid at 10° to 15°C. After a short standing, the reaction mixture was poured onto ice and rendered alkaline by means of a sodium hydroxide solution. By extraction with ether, there was obtained 1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-amino-isoquinoline. The base is reacted with maleic acid to give the maleate; melting point of the maleate 199° to 201°C (from ethanol).

brand name

Merital (Hoechst-Roussel).

Therapeutic Function

Psychostimulant

Biochem/physiol Actions

Nomifensine maleate is a selective dopamine uptake inhibitor interacting with the dopamine transporter, at a site different from that of cocaine; antidepressant. Nomifensine serves as an antidepressant and is known to cause frequent hemolytic anemia. The aniline group in this compound results in blood and liver toxicities.

Safety Profile

Poison by ingestion,subcutaneous, intravenous, and intraperitoneal routes.Human systemic effects by intravenous route: heart ratechanges, blood pressure elevation. Experimentalreproductive effects. An antidepressant. When heated to decomposition it em

storage

Store at +4°C

NOMIFENSINE MALEATE SALT Preparation Products And Raw materials

Raw materials

Sulfuric acid Hydrogen Sodium borohydride Maleic acid

Preparation Products

NOMIFENSINE MALEATE SALT Suppliers

Global( 81)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7545 61
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8039 58
Nanjing Chalf-Pharm Technology Co., Ltd. 025-57018978 18251899859 sales@chalf-pharm.com China 5855 50
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Chemsky（shanghai）International Co.,Ltd. 50
BOC Sciences 65
Haoyuan Chemexpress Co., Ltd. 61
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
MedChemexpress LLC 58
Shanghai TaoSu Biochemical Technology Co., Ltd. 58
Nanjing Chalf-Pharm Technology Co., Ltd. 50
Sigma-Aldrich 80
EMMX Biotechnology LLC 60

View Lastest Price from NOMIFENSINE MALEATE SALT manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NOMIFENSINE MALEATE SALT USP/EP/BP pictures 2026-08-20 NOMIFENSINE MALEATE SALT USP/EP/BP
32795-47-4
 $1.10 1g 99.9% 100 Tons min Dideu Industries Group Limited
Nomifensine maleate pictures 2026-08-03 Nomifensine maleate
32795-47-4
 $30.00-64.00 98.70% 10g TargetMol Chemicals Inc.

NOMIFENSINE MALEATE SALT Spectrum

NOMIFENSINE MALEATE SALT(32795-47-4)MSNOMIFENSINE MALEATE SALT(32795-47-4)1HNMR

32795-47-4(NOMIFENSINE MALEATE SALT)Related Search:

Chlorphenamine maleate N-(5-Chloro-2-pyridinyl)-2-[[4-[(dimethylamino)iminomethyl]benzoyl]amino]-5-methoxybenzamide (2Z)-2-butenedioate (1:1) NOMIFENSINE MALEATE Phenramine maleate Maleic acid monosodium salt
2-Dimethylaminomethyl-aniline Ammonium hydrogen maleate 4-phenyl-1,2,3,4-tetrahydroisoquinoline NOMIFENSINE MALEATE SALT

1of2

1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolinamin(z)-2-butenedioate 1,2,3,4-tetrahydro-8-amino-2-methyl-4-phenyl-isoquinolinmaleate 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium-8-amine 1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine maleate 8-amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolinemaleate alival(antidepressant) hoe984 hostalival meritalam nomifensinehydrogenmaleate nomifensinhydrogenmaleate NOMIFENSINE MALEATE NOMIFENSINE MALEATE SALT 8-ammonio-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinolinium maleate Alival NSC-289114 1,2,3,4-TETRAHYDRO-2-METHYL-4-PHENYL-8-ISOQUINOLINAMINE MALEATE SALT (±)-Nomifensine maleat Nomifensine Maleic Acid Salt NOMIFENSINE MALEATE SALT USP/EP/BP 2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine maleate Dopamine Receptor,inhibit,Inhibitor,Nomifensine maleate,Nomifensine 8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-, (2Z)-2-butenedioate (1:1) Nomifensine maleate, 10 mM in DMSO merital 32795-47-4 C16H18N2C4H4O4 Inhibitors API Heterocycles series