ChemicalBook >> CAS DataBase List >>5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine

5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine

5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine structure

CAS No.: 134031-86-0

Chemical Name:: 5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine

Synonyms: 2'-OMe-U Phosphoramidite;DMT-dT-CE Reverse Phosphoramidite;Rev T-5’-amidite;idT phosphoramidite;Rev T (Bz)-5’-amidite;idT CE Phosphoramidite;2'-OMe-UPhosphoramidite,97%;2'-OMe-rU-CE Phosphoramidite;DMT-dT-CE-Inverted-Phosphoramidite;DMT-dT-5'-CE Reverse Phosphoramidite

CBNumber:: CB7204898

Molecular Formula:: C40H49N4O8P

Molecular Weight:: 744.81

MDL Number:: MFCD08706371

MOL File:: 134031-86-0.mol

MSDS File:: SDS

Last updated:2026-09-12 18:54:44

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5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine Properties

storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO: Sparingly soluble: 1-10 mg/ml Ethanol: Sparingly soluble: 1-10 mg/ml
pka	9.55±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Warning

Hazard statements

H301-H315-H319-H335

Precautionary statements

P261-P280a-P301+P310a-P305+P351+P338-P405-P501a

HS Code

29349990

NFPA 704

	1
2		0

5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine price More Price(29)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	43278	2''-OMe-U Phosphoramidite ≥98%	134031-86-0	50mg	$138	2026-04-30	Buy
Cayman Chemical	43278	2''-OMe-U Phosphoramidite ≥98%	134031-86-0	100mg	$235	2026-04-30	Buy
Cayman Chemical	43278	2''-OMe-U Phosphoramidite ≥98%	134031-86-0	250mg	$379	2026-04-30	Buy
Cayman Chemical	43278	2''-OMe-U Phosphoramidite ≥98%	134031-86-0	500mg	$688	2026-04-30	Buy
Biosynth	PD09188	3'-O-DMT-thymidine 5'-CE phosphoramidite	134031-86-0	100mg	$189	2026-06-04	Buy

Product number	Packaging	Price	Buy
43278	50mg	$138	Buy
43278	100mg	$235	Buy
43278	250mg	$379	Buy
43278	500mg	$688	Buy
PD09188	100mg	$189	Buy

5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine Chemical Properties, Uses, Production

Description

2'-OMe-U Phosphoramidite can be for incorporation of an (otherwise unmodified) reverse (5' to 3') dT nucleobase within an oligonucleotide.

Uses

3’-O-DMTr-thymidine 5’-CE phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] W. MIACHEL HANSON. Reversible Oligonucleotide Chain Blocking Enables Bead Capture and Amplification of T-Cell Receptor α and β Chain mRNAs[J]. Journal of the American Chemical Society, 2016, 138 35: 11073-11076. DOI: 10.1021/jacs.6b04465

5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine Preparation Products And Raw materials

Raw materials

Preparation Products

5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine Suppliers

Global Suppliers ( 91)

Supplier	Tel	Email	Country	ProdList	Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Hongene Biotech Corporation	021-64757213	info@hongene.com	China	672	61
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Chengdu Pukang Biotechnology Co., Ltd	18217049878	cassie.gao@pu-kang.com	China	480	58
Shanghai T&W Pharmaceutical Co., Ltd.	+86 21 61551611		China	9874	58
Shenzhen HwaGen Pharmaceutical Co.,Ltd	Q:3003761227 17722620669	liangcong.yi@rafflespt.com	China	274	58
9ding chemical ( Shanghai) Limited	4009209199	sales@9dingchem.com	China	22497	55
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Tianjin Scaxchem Limited Compnay	18630949181	sales@cosychem.com	China	657	55

Supplier	Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Hongene Biotech Corporation	61
Alfa Aesar	84
Nanjing Chemlin Chemical Co., Ltd	64
Chengdu Pukang Biotechnology Co., Ltd	58
Shanghai T&W Pharmaceutical Co., Ltd.	58
Shenzhen HwaGen Pharmaceutical Co.,Ltd	58
9ding chemical ( Shanghai) Limited	55
Bide Pharmatech Ltd.	60
Tianjin Scaxchem Limited Compnay	55

View Latest Price from 5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-11	3'-O-DMTr-thymidine 5'-CE phosphoramidite 134031-86-0	$32.00-70.00		99.42%	10g	TargetMol Chemicals Inc.

3'-O-DMTr-thymidine 5'-CE phosphoramidite
134031-86-0
$32.00-70.00
99.42%
TargetMol Chemicals Inc.

5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine Spectrum

5'-O-[(N,N-DIISOPROPYLAMINO)-(2-CYANOETHOXY)PHOSPHINYL]-3'-O-(4,4'-DIMETHOXYTRITYL)-THYMIDINE(134031-86-0)¹HNMR

134031-86-0 (5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine) Related Search:

2'-F-ibu-dG Phosphoramidite 2'-F-Bz-dC Phosphoramidite 2’-O-Methyl-rA(N-Bz)phosphoramidite DMT-dG(dmf) Phosphoramidite DMT-2′O-Methyl-rC(ac) Phosphoramidite

2'-OMe-ibu-G Phosphoramidite 5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine 3'-O-(4,4'-dimethoxytrityl)-thymidine

1of2

2'-OMe-rU-CE Phosphoramidite 5'-O-[(DiisopropylaMino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-diMethoxytrityl)thyMidine, 97% 3'-O-DMT-thymidine 5'-CE phosphoramidite 3'-O-[Bis(4-methoxyphenyl)phenylmethyl]thymidine 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] 2'-O-Methyl-5'-O-DMT-Uridine-3'-CE-Phosphoramidite 3'-O-(4,4'-Dimethoxytrityl)-thymidine-5'-cyanoethyl-Phosphoramidite DMT-dT-5'-CE Reverse Phosphoramidite Thymidine, 3'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] 3’-O-DMTr-thymidine 5’-CE phosphoramidite 3'-Dimethoxytrityl-2'-deoxyThymidine,5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite Rev T-5’-amidite 2'-OMe-UPhosphoramidite,97% 3-DMT Thymidine 5-CED phosphoramidite 3'-O-DMTr-thymidine 5'-CE phosphoramidite,97% 5'-O-[(Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)thymidine DMT-dT-CE-Inverted-Phosphoramidite 3’-O-DMTr-thymidine ? 5’-CE phosphoramidite idT CE Phosphoramidite idT phosphoramidite 3’-O-DMTr-thymidine-5’-O-CED-phosphoramidite Rev T (Bz)-5’-amidite 2'-OMe-U Phosphoramidite DMT-dT-CE Reverse Phosphoramidite 5'-O-[(N,N-Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-thymidine 134031-86-0 RNAi Phosphoramidite