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4-Methoxy-1-naphthaldehyde

CAS No.
15971-29-6
Chemical Name:
4-Methoxy-1-naphthaldehyde
Synonyms
AKOS B022255;TIMTEC-BB SBB000256;4-Methoxy-1-Naphtol;4-METHOXY-1-NAPHTHALDEHYDE;4-Methoxy-1-naphthylaldehyde;4-methoxy-1-naphthalaldehyde;1-Naphthaldehyde, 4-methoxy-;4-Methoxy-1-naphthaldehyde>4-Methoxy-1-naphthaldehyde,99%;4-monomethoxy-1-naphthaldehyde
CBNumber:
CB7207516
Molecular Formula:
C12H10O2
Molecular Weight:
186.21
MDL Number:
MFCD00004006
MOL File:
15971-29-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:20:50

4-Methoxy-1-naphthaldehyde Properties

Melting point 35-36 °C(lit.)
Boiling point 212 °C40 mm Hg(lit.)
Density 1.1879
refractive index 1.6640
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Low Melting Solid
color Slightly beige to pink-brown
Sensitive Air Sensitive
BRN 2046436
InChI 1S/C12H10O2/c1-14-12-7-6-9(8-13)10-4-2-3-5-11(10)12/h2-8H,1H3
InChIKey MVXMNHYVCLMLDD-UHFFFAOYSA-N
SMILES COc1ccc(C=O)c2ccccc12
CAS DataBase Reference 15971-29-6(CAS DataBase Reference)
FDA UNII E2L48UL293
NIST Chemistry Reference 1-Naphthalenecarboxaldehyde, 4-methoxy-(15971-29-6)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Risk Statements  36/37/38
Safety Statements  24/25
WGK Germany  3
HS Code  29124990
Storage Class 11 - Combustible Solids
NFPA 704
0
0 0

4-Methoxy-1-naphthaldehyde price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 103241 4-Methoxy-1-naphthaldehyde 99% 15971-29-6 10g $225 2026-04-30 Buy
TCI Chemical M1049 4-Methoxy-1-naphthaldehyde >97.0%(GC) 15971-29-6 5g $137 2026-04-30 Buy
Usbiological 283009 4-Methoxy-1-naphthaldehyde Asreported 15971-29-6 10g $366 2026-06-03 Buy
Usbiological 283009 4-Methoxy-1-naphthaldehyde Asreported 15971-29-6 25g $542 2026-06-03 Buy
Usbiological 283009 4-Methoxy-1-naphthaldehyde Asreported 15971-29-6 50g $761 2026-06-03 Buy
Product number Packaging Price Buy
103241 10g $225 Buy
M1049 5g $137 Buy
283009 10g $366 Buy
283009 25g $542 Buy
283009 50g $761 Buy

4-Methoxy-1-naphthaldehyde Chemical Properties,Uses,Production

Chemical Properties

slightly beige to pink-brown low melting solid

Uses

4-Methoxy-1-naphthaldehyde was used in fluorometric enzymatic assay for determination of activity of class I and II alcohol dehydrogenase isoenzymes in human pancreas and in human liver homogenates.

Biochem/physiol Actions

4-Methoxy-1-naphthaldehyde is fluorogenic substrate for human alcohol dehydrogenase (ADH).

Synthesis

4-Hydroxy-1-naphthaldehyde

7770-45-8

Iodomethane

74-88-4

4-Methoxy-1-naphthaldehyde

15971-29-6

General method: A mixture of 4-hydroxy-1-naphthaldehyde (1 eq.), potassium carbonate (K2CO3, 1.5 eq.) and iodomethane (1.5 eq.) in acetone (12 mL/mmol) was stirred under reflux conditions for 4 to 24 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) until complete disappearance of the raw material. Upon completion of the reaction, the solvent was removed by evaporation under reduced pressure. The residue was purified by silica gel column chromatography with an eluent ratio of cyclohexane/ethyl acetate (90:10 to 70:30).

References

[1] Physical Chemistry Chemical Physics, 2015, vol. 17, # 15, p. 10238 - 10249
[2] European Journal of Medicinal Chemistry, 2016, vol. 123, p. 161 - 170
[3] Justus Liebigs Annalen der Chemie, 1907, vol. 357, p. 373
[4] Journal of the American Chemical Society, 1982, vol. 104, # 16, p. 4469 - 4477
[5] Journal of Medicinal Chemistry, 2012, vol. 55, # 20, p. 8969 - 8973

4-Methoxy-1-naphthaldehyde Preparation Products And Raw materials

Global( 148)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
SelectLab Chemicals GmbH +49-(0)2383-919350 info@selectlab.de Germany 393 55
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
China Langchem Inc. 0086-21-58956006 China 7798 57

View Lastest Price from 4-Methoxy-1-naphthaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Methoxy-1-naphthaldehyde pictures 2026-08-13 4-Methoxy-1-naphthaldehyde
15971-29-6
1KG 98% 2000 Shenzhen Nexcon Pharmatechs Ltd.
4-Methoxy-1-naphthaldehyde pictures 2023-07-19 4-Methoxy-1-naphthaldehyde
15971-29-6
$30.00 1KG 99% 20 Tons Wuhan wingroup Pharmaceutical Co., Ltd
	4-Methoxy-1-naphthaldehyde pictures 2019-09-03 4-Methoxy-1-naphthaldehyde
15971-29-6
$7.00 1KG 99% Career Henan Chemical Co
4-METHOXY-1-NAPHTHALDEHYDE AKOS B022255 2-(2-methyl-1-oxo-3,4-dihydronaphthalen-2-yl)acetic acid TIMTEC-BB SBB000256 1-Naphthaldehyde, 4-methoxy- 4-Methoxy-1-naphthalenecarboxaldehyde 4-Methoxy-naphthalene-1-carbaldehyde 4-methoxy-1-naphthalaldehyde 4-Methoxy-1-naphthylaldehyde 4-Methoxy-1-naphthaldehyde,99% 4-Methoxy-1-naphthaldehyde, 99% 10GR 1-Naphthalenecarboxaldehyde, 4-methoxy- 4-monomethoxy-1-naphthaldehyde 4-Methoxy-1-naphthaldehyde> 4-Methoxy-1-Naphtol 15971-29-6 Building Blocks Aldehydes C10 to C21 Carbonyl Compounds ALDEHYDE Organic Building Blocks Aldehydes C10 to C21 Carbonyl Compounds