4-Methylumbelliferyl oleate
- CAS No.
- 18323-58-5
- Chemical Name:
- 4-Methylumbelliferyl oleate
- Synonyms
- 4-MU-OLEATE;Einecs 242-210-7;4-Methylumbelliferyl oleate;4-Methylumbelliferone oleate;Oleoyl 4-MethyluMbelliferone;4-MethylumbelliferylOleateA.R.;7-Hydroxy-4-MethylcouMarin Oleate;4-methylumbrellaketoneoleate，4-MUO;OLEIC ACID-4-METHYLUMBELLIFERYL ESTER;4-Methyl-2-oxo-2H-chroMen-7-yl oleate
- CBNumber:
- CB7212923
- Molecular Formula:
- C28H40O4
- Molecular Weight:
- 440.61
- MDL Number:
- MFCD00076095
- MOL File:
- 18323-58-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 37-38 °C (lit.) |
|---|---|
| Boiling point | 471.81°C (rough estimate) |
| Density | 1.023 |
| refractive index | 1.4840 (estimate) |
| Flash point | 281.3℃ |
| storage temp. | -20°C |
| solubility | 2-methoxyethanol: soluble |
| form | Solid |
| color | Colorless to Pale Yellow Oil |
| Appearance | Solid Powder |
| BRN | 4887028 |
| InChI | 1S/C28H40O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-27(29)31-24-19-20-25-23(2)21-28(30)32-26(25)22-24/h10-11,19-22H,3-9,12-18H2,1-2H3/b11-10- |
| InChIKey | NKQFKJYKCVDLPT-KHPPLWFESA-N |
| SMILES | CCCCCCCC\C=C/CCCCCCCC(=O)Oc1ccc2C(C)=CC(=O)Oc2c1 |
| CAS DataBase Reference | 18323-58-5(CAS DataBase Reference) |
| UNSPSC Code | 12352204 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| F | 8-10 |
| HS Code | 29322090 |
| Storage Class | 11 - Combustible Solids |
4-Methylumbelliferyl oleate price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 75164 | 4-Methylumbelliferyl oleate suitable for fluorescence, ≥95% (HPCE) | 18323-58-5 | 25mg | $109 | 2026-04-30 | Buy |
| Sigma-Aldrich | 75164 | 4-Methylumbelliferyl oleate suitable for fluorescence, ≥95% (HPCE) | 18323-58-5 | 100mg | $337 | 2026-04-30 | Buy |
| Cayman Chemical | 19590 | 4-Methylumbelliferyl Oleate ≥98% | 18323-58-5 | 25mg | $53 | 2026-04-30 | Buy |
| Cayman Chemical | 19590 | 4-Methylumbelliferyl Oleate ≥98% | 18323-58-5 | 50mg | $94 | 2026-04-30 | Buy |
| Cayman Chemical | 19590 | 4-Methylumbelliferyl Oleate ≥98% | 18323-58-5 | 100mg | $134 | 2026-04-30 | Buy |
4-Methylumbelliferyl oleate Chemical Properties, Uses, Production
Description
4-Methylumbelliferyl (4-MU) oleate is a fluorogenic substrate for acid and alkaline lipases. It is cleaved by lipases, liberating 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.
Chemical Properties
Colourless Oil
Uses
4-Methylumbelliferyl oleate can act as Fatty acyl esters for use as fluorogenic substrates to continuously follow the hydrolytic activity of carboxylesterases, such as acid and alkaline lipases.
Uses
Fluorogenic substrate for lipases.
Uses
4-Methylumbelliferyl oleate has been used:
- as a substrate to assay the activity of non-specific esterases
- to determine lipase activity
- as a substrate to evaluate pancreatic lipase inhibitory activity
References
[1] M L ARMSTRONG. Lipid metabolism in xanthomatous skin of hypercholesterolemic rabbits.[J]. American Journal of Pathology, 1986, 125 2: 339-348.
[2] BERNARD J MONCLA K M P. Oleate lipase activity in Gardnerella vaginalis and reconsideration of existing biotype schemes.[J]. ACS Applied Energy Materials, 2009: 78. DOI: 10.1186/1471-2180-9-78
[3] AKIHIRO OGAWA. Lactobacillus gasseri SBT2055 suppresses fatty acid release through enlargement of fat emulsion size in vitro and promotes fecal fat excretion in healthy Japanese subjects.[J]. Lipids in Health and Disease, 2015, 14: 20. DOI: 10.1186/s12944-015-0019-0
Excitation / Emission Maximum
330 nm (pH 4.6), 370 nm (pH 7.4), 385 nm (pH 10.4)/445-454 nm
4-Methylumbelliferyl oleate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Xingui Biotechnology Co., Ltd. | 15121041756 | xingui2022@126.com | China | 9985 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
View Latest Price from 4-Methylumbelliferyl oleate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | 4-Methylumbelliferyl oleate
18323-58-5
|
$30.00-68.00 | 99.64% | 10g | TargetMol Chemicals Inc. |
-
- 4-Methylumbelliferyl oleate
18323-58-5
- $30.00-68.00
- 99.64%
- TargetMol Chemicals Inc.
