D,L-Tryptophan Methyl Ester Hydrochloride
- CAS No.
- 5619-09-0
- Chemical Name:
- D,L-Tryptophan Methyl Ester Hydrochloride
- Synonyms
- NSC 34498;H-DL-Trp-OMe;DL-Trp-OMe·HCl;H-DL-TRP-OME HCL;TIMTEC-BB SBB003122;DL-TRYPTOPHAN-OME HCL;DL-TRYPTOPHAN METHYL ESTER HCL;DL-Tryptophan Methyl ester hydrochlorede;DL-TRYPTOPHAN METHYL ESTER HYDROCHLORIDE;DL-Trvptophan methvl ester hvdrochloride
- CBNumber:
- CB7214907
- Molecular Formula:
- C12H15ClN2O2
- Molecular Weight:
- 254.71
- MDL Number:
- MFCD00066133
- MOL File:
- 5619-09-0.mol
| Melting point | 221-222 |
|---|---|
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Methanol, Water |
| form | Solid |
| color | Off-white to white |
| InChI | InChI=1S/C12H14N2O2.ClH/c1-16-12(15)10(13)6-8-7-14-11-5-3-2-4-9(8)11;/h2-5,7,10,14H,6,13H2,1H3;1H |
| InChIKey | XNFNGGQRDXFYMM-UHFFFAOYSA-N |
| SMILES | C12C=CC=CC=1NC=C2CC(N)C(=O)OC.Cl |
| CAS DataBase Reference | 5619-09-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338-P362+P364 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2933998090 | |||||||||
| NFPA 704 |
|
D,L-Tryptophan Methyl Ester Hydrochloride price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | T9020-30 | D,L-Tryptophan Methyl Ester, Hydrochloride | 10g | $403 | 2026-06-04 | Buy | |
| Usbiological | 290494 | D,L-Tryptophan methyl ester hydrochloride | 5619-09-0 | 1g | $287 | 2026-06-03 | Buy |
| Usbiological | 290494 | D,L-Tryptophan methyl ester hydrochloride | 5619-09-0 | 2g | $382 | 2026-06-03 | Buy |
| Usbiological | 290494 | D,L-Tryptophan methyl ester hydrochloride | 5619-09-0 | 5g | $492 | 2026-06-03 | Buy |
| Usbiological | 290494 | D,L-Tryptophan methyl ester hydrochloride | 5619-09-0 | 10g | $623 | 2026-06-03 | Buy |
D,L-Tryptophan Methyl Ester Hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Amino acid derivative， D,L-Tryptophan Methyl Ester Hydrochloride may be used to prepare the corresponding amino acid amide L-Tryptophanamide Hydrochloride (Cat. #T89550)
Uses
Amino acid derivative that may be used to prepare the corresponding amino acid amide L-Tryptophanamide Hydrochloride (Cat. #T89550).
Synthesis
67-56-1
73-22-3
7524-52-9
The general procedure for the synthesis of L-tryptophan methyl ester hydrochloride from methanol and L-tryptophan was as follows: L-tryptophan (18.2 mmol) was dissolved in methanol (20 mL) at 0 °C with stirring. Thionyl chloride (1.6 mL, 22 mmol) was added slowly and dropwise over 10 min. Subsequently, the reaction mixture was gradually warmed to room temperature and heated under reflux conditions for 3 hours. Upon completion of the reaction, the solvent and volatiles were removed by distillation under reduced pressure. The resulting product was ground with ethyl acetate to give L-tryptophan methyl ester hydrochloride as a colorless solid in 100% yield. The product was a white solid with a yield of 4.63 g. Its 1H NMR (400 MHz, CD3OD) and 13C NMR (100 MHz, CD3OD) data were consistent with those reported in the literature, confirming the structure and purity of the product.
References
[1] Tetrahedron, 2001, vol. 57, # 51, p. 10181 - 10189
[2] Patent: US2014/206741, 2014, A1. Location in patent: Paragraph 0111
[3] European Journal of Medicinal Chemistry, 2016, vol. 114, p. 318 - 327
[4] New Journal of Chemistry, 2018, vol. 42, # 16, p. 13549 - 13557
[5] Organic and Biomolecular Chemistry, 2014, vol. 12, # 41, p. 8280 - 8287
D,L-Tryptophan Methyl Ester Hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yangzhou Xuda Biotechnology Co., Ltd | 15161820588; 15161820588 | xdchemical2024@163.com | China | 91 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
View Lastest Price from D,L-Tryptophan Methyl Ester Hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | DL-Trp-Ome.HCl
5619-09-0
|
1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
 |
2020-01-09 | D,L-Tryptophan Methyl Ester Hydrochloride
5619-09-0
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- DL-Trp-Ome.HCl
5619-09-0
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- D,L-Tryptophan Methyl Ester Hydrochloride
5619-09-0
- $1.00
- 99%
- Career Henan Chemical Co
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