(+/-)-EPIBATIDINE
- CAS No.
- 140111-52-0
- Chemical Name:
- (+/-)-EPIBATIDINE
- Synonyms
- (+)-Epibatidine;(+/-)-EPIBATIDINE;(+/-)-EpibatidineHCl;(+/-)-EPIBATIDINE USP/EP/BP;(+-)-EPIBATIDINE DIHYDROCHLORIDE SYNTHET IC >99%;2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane;(±)-exo-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1]heptane;(2R,4S)-2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane;7-Azabicyclo(2.2.1)heptane, 2-(6-chloro-3-pyridinyl)-, exo-;7-Azabicyclo(2.2.1)heptane, 2-(6-chloro-3-pyridinyl)-, (1R,2R,4S)-
- CBNumber:
- CB7217832
- Molecular Formula:
- C11H13ClN2
- Molecular Weight:
- 208.69
- MDL Number:
- MFCD00923801
- MOL File:
- 140111-52-0.mol
- MSDS File:
- SDS
| Boiling point | 336.7±32.0 °C(Predicted) |
|---|---|
| Density | 1.223±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at +4°C |
| form | White solid. |
| pka | 10.07±0.40(Predicted) |
| EWG's Food Scores | 1 |
| FDA UNII | M6K314F1XX |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300-H310 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501 |
(+/-)-EPIBATIDINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 448307 | (+)-Epibatidine ≥99%(HPLC) | 140111-52-0 | 5mg | $885 | 2026-06-03 | Buy |
| AHH | MT-11688 | (+/-)-Epibatidine 97% | 0.01g | $298 | 2026-05-26 | Buy | |
| AccelPharmtech | C1216 | (1R,2R,4S)-2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane 97.00% | 140111-52-0 | 1G | $6060 | 2026-05-21 | Buy |
| AccelPharmtech | C1216 | (1R,2R,4S)-2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane 97.00% | 140111-52-0 | 5G | $10600 | 2026-05-21 | Buy |
| AccelPharmtech | C1216 | (1R,2R,4S)-2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane 97.00% | 140111-52-0 | 25G | $21200 | 2026-05-21 | Buy |
(+/-)-EPIBATIDINE Chemical Properties,Uses,Production
Uses
(+)-Epibatidine has binding affinities for α4β2 and α3β4 nicotinic receptors.
Synthesis Reference(s)
[1] Simon C. Clayton,Andrew C. Regan. A total synthesis of (±)-epibatidine. Tetrahedron Letters. Volume 34, Issue 46, 12 November 1993, Pages 7493-7496.
Biological Activity
Very potent nicotinic agonist (K i values are 0.02 and 233 nM for α 4 β 2 and α 7 nicotinic receptors respectively). Analgesic.
Synthesis
Andrew C. Regan and colleagues reported a total synthesis of the potent non-opiate analgesic alkaloid epibatidine is described, in which the key step is a reductive palladium-catalysed Heck-type coupling.[1] (±)-Epibatidine has being synthesised, employing a reductive palladium-catalysed coupling as the key reaction.
(+/-)-EPIBATIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
(+/-)-EPIBATIDINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29091 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 13308200041 | 2851167782@qq.com | China | 10763 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
| Qingdao Haizhi Weiyuan Biotechnology Co., Ltd. | 18317699790 18317699790 | l202008112023@163.com | China | 7733 | 58 |
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