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2-Bromo-4-cyanothiazole

CAS No.
848501-90-6
Chemical Name:
2-Bromo-4-cyanothiazole
Synonyms
2-bromo-1,3-thiazole-4-carbonitrile;2-Bromo-4-cyanothiazole;2-bromo-4-thiazolecarbonitrile;4-Thiazolecarbonitrile, 2-broMo-
CBNumber:
CB72452776
Molecular Formula:
C4HBrN2S
Molecular Weight:
189.03
MDL Number:
MFCD09909650
MOL File:
848501-90-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:50

2-Bromo-4-cyanothiazole Properties

Boiling point 276.1±13.0 °C(Predicted)
Density 1.97±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -3.33±0.10(Predicted)
Appearance Off-white to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2934100090

2-Bromo-4-cyanothiazole price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR962783 2-Bromo-4-cyanothiazole >97% 848501-90-6 250mg $21 2026-06-04 Buy
Apolloscientific OR962783 2-Bromo-4-cyanothiazole >97% 848501-90-6 1g $29 2026-06-04 Buy
Apolloscientific OR962783 2-Bromo-4-cyanothiazole >97% 848501-90-6 5g $130 2026-06-04 Buy
Apolloscientific OR962783 2-Bromo-4-cyanothiazole >97% 848501-90-6 25g $592 2026-06-04 Buy
Apolloscientific OR962783 2-Bromo-4-cyanothiazole >97% 848501-90-6 100g $2153 2026-06-04 Buy
Product number Packaging Price Buy
OR962783 250mg $21 Buy
OR962783 1g $29 Buy
OR962783 5g $130 Buy
OR962783 25g $592 Buy
OR962783 100g $2153 Buy

2-Bromo-4-cyanothiazole Chemical Properties, Uses, Production

Synthesis

2-BROMO-THIAZOLE-4-CARBOXAMIDE

848501-94-0

2-BROMO-4-CYANOTHIAZOLE

848501-90-6

The general procedure for synthesizing 2-bromo-4-cyanothiazole using 2-bromothiazole-4-carboxamide as starting material is as follows: General method: after completing the preparation of the amide intermediate (Example A), the state of the reaction vessel is determined according to the boiling point of the amide intermediate. If the boiling point of the amide intermediate at atmospheric pressure is equal to or lower than the set reaction temperature (TB), the reaction vessel is closed; if the boiling point is higher than the TB, the reaction vessel is kept open. Subsequently, stirring is continued at a rate of 600 rpm and the reaction temperature is adjusted to TB. this temperature (TB) is maintained for a continuous period of TD hours until the reaction is nearly complete. Next, the reaction vessel was sealed and connected to a vacuum pump, the vacuum in the reaction vessel was adjusted to 20-50 mbar (depending on the nature of the nitrile product) and the distillate was collected as the nitrile product. The yield of the nitrile product was calculated, and samples were taken for NMR spectroscopy and elemental analysis to characterize the resulting nitrile product. The specific reaction conditions and characterization results are detailed in Tables A-7, A-8, A-9, A-10 and A-11. The characterization results showed that the obtained nitrile product was of very high purity (>99%). In some embodiments of the preparation of the nitrile product, 10 g of phosphorus pentoxide can be selectively added as a catalyst at the initial stage of the reaction.

References

[1] Patent: CN104557357, 2018, B. Location in patent: Paragraph 0150; 0151; 0152; 0162
[2] Patent: WO2011/109799, 2011, A1. Location in patent: Page/Page column 225

2-Bromo-4-cyanothiazole Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 88)
Supplier Tel Email Country ProdList Advantage
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4263 65
China Langchem Inc. 0086-21-58956006 China 7798 57
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9509 58
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
Shanghai Keepontech Co.,Ltd 021-54849683 13601642561 sales@keepontech.com China 998 59
Xunteng International Trading Co.,Limited China Hong Kong 876 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60

View Latest Price from 2-Bromo-4-cyanothiazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-BROMO-4-CYANOTHIAZOLE pictures 2019-07-11 2-BROMO-4-CYANOTHIAZOLE
848501-90-6
$3.00 1KG 99 100kg Career Henan Chemical Co

2-Bromo-4-cyanothiazole Spectrum

2-bromo-4-thiazolecarbonitrile 2-bromo-1,3-thiazole-4-carbonitrile 4-Thiazolecarbonitrile, 2-broMo- 2-Bromo-4-cyanothiazole 848501-90-6 C4HBrN2S