Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Chlorothieno[3,2-d]pyrimidine

2-Chlorothieno[3,2-d]pyrimidine

2-Chlorothieno[3,2-d]pyrimidine Structure
2-Chlorothieno[3,2-d]pyrimidine structure
CAS No.
1119280-68-0
Chemical Name:
2-Chlorothieno[3,2-d]pyrimidine
Synonyms
2-Chlorothieno[3,2-d]pyrimidine;Thieno[3,2-d]pyrimidine, 2-chloro-;2-Chlorothieno[3,2-d]pyrimidine ISO 9001：2015 REACH
CBNumber:
CB72471265
Molecular Formula:
C6H3ClN2S
Molecular Weight:
170.62
MDL Number:
MFCD12406127
MOL File:
1119280-68-0.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:40
Request For Quotation

2-Chlorothieno[3,2-d]pyrimidine Properties

Melting point 165-166℃
Density 1.531
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form solid
pka -0.06±0.40(Predicted)
Appearance White to off-white Solid
InChI InChI=1S/C6H3ClN2S/c7-6-8-3-5-4(9-6)1-2-10-5/h1-3H
InChIKey QKRVOGZPQVCVPZ-UHFFFAOYSA-N
SMILES C1(Cl)=NC=C2SC=CC2=N1
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

HazardClass  IRRITANT
HS Code  2934999090

2-Chlorothieno[3,2-d]pyrimidine price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech 50267 2-CHLOROTHIENO[3,2-D]PYRIMIDINE 97% 1119280-68-0 0.25G $99 2026-04-30 Buy
AstaTech 50267 2-CHLOROTHIENO[3,2-D]PYRIMIDINE 97% 1119280-68-0 1G $129 2026-04-30 Buy
AstaTech 50267 2-CHLOROTHIENO[3,2-D]PYRIMIDINE 97% 1119280-68-0 5G $499 2026-04-30 Buy
Apolloscientific OR963899 2-Chlorothieno[3,2-d]pyrimidine 98% 1119280-68-0 250mg $77 2026-06-04 Buy
Apolloscientific OR963899 2-Chlorothieno[3,2-d]pyrimidine 98% 1119280-68-0 1g $123 2026-06-04 Buy
Product number Packaging Price Buy
50267 0.25G $99 Buy
50267 1G $129 Buy
50267 5G $499 Buy
OR963899 250mg $77 Buy
OR963899 1g $123 Buy

2-Chlorothieno[3,2-d]pyrimidine Chemical Properties, Uses, Production

Synthesis

2,4-Dichlorothieno[3,2-d]pyrimidine

16234-14-3

2-Chlorothieno[3,2-d]pyrimidine

1119280-68-0

GENERAL STEPS: 2,4-Dichlorothieno[3,2-d]pyrimidine (19 g, 58 mmol) was dissolved in a solvent mixture of ethanol (25 mL) and ethyl acetate (25 mL). To this solution was added sodium bicarbonate (1.1 g, 13.1 mmol) followed by 10% palladium carbon catalyst (0.206 g). The reaction mixture was stirred under hydrogen atmosphere for 5 h. The reaction progress was monitored by liquid chromatography-mass spectrometry (LC-MS) to confirm the formation of 2-chlorothieno[3,2-d]pyrimidine. Upon completion of the reaction, the mixture was filtered through diatomaceous earth to remove the catalyst and the filtrate was concentrated under reduced pressure to afford the off-white solid product 2-chlorothieno[3,2-d]pyrimidine (0.990 g, quantitative yield). The structure of the product was confirmed by 1H NMR (CDCl3): δ 9.17 (s, 1H), 8.16-8.12 (d, 1H), 7.55-7.51 (d, 1H).

References

[1] Patent: WO2011/79231, 2011, A1. Location in patent: Page/Page column 82
[2] Patent: WO2009/62258, 2009, A1. Location in patent: Page/Page column 91
[3] ACS Medicinal Chemistry Letters, 2011, vol. 2, # 2, p. 154 - 159
[4] Patent: WO2012/78859, 2012, A2. Location in patent: Page/Page column 59
[5] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 7, p. 2113 - 2122

2-Chlorothieno[3,2-d]pyrimidine Preparation Products And Raw materials

Raw materials

2,4-Dichlorothieno[3,2-d]pyrimidine Hydrogen Sodium bicarbonate Ethyl acetate Ethanol

Preparation Products

2-Chlorothieno[3,2-d]pyrimidine Suppliers

Global Suppliers ( 117)
Supplier Tel Email Country ProdList Advantage
Suzhou Zehou Biotechnology Co. , Ltd. 0512-68716880 19984816880 sales@growingchem.com China 229 64
Shanghai Leiming Medical Technology Co., LTD 13761371720 zhangleitao111@sina.com China 475 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Shangchem Co., Ltd. +86-21-68182121 China 881 52
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
China Langchem Inc. 0086-21-58956006 China 7798 57
Shanghai AmasPharm Co., Ltd. 021-54540637 18621091017 sales@amaspharm.com China 787 62
Atop-Pharma (Shanghai) Technology Co., Ltd. +86 (21) 5196-9732 China 996 57
ZhengZhou HuaWen Chemical Co.Ltd 0370-2785118 17550508557 675141927@qq.com China 3201 55
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9509 58
Supplier Advantage
Suzhou Zehou Biotechnology Co. , Ltd. 64
Shanghai Leiming Medical Technology Co., LTD 58
J & K SCIENTIFIC LTD. 76
Shangchem Co., Ltd. 52
Pure Chemistry Scientific Inc. 62
China Langchem Inc. 57
Shanghai AmasPharm Co., Ltd. 62
Atop-Pharma (Shanghai) Technology Co., Ltd. 57
ZhengZhou HuaWen Chemical Co.Ltd 55
Shanghai Topbiochem Technology Co., Ltd 58

View Latest Price from 2-Chlorothieno[3,2-d]pyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chlorothieno[3,2-d]pyrimidine pictures 2025-06-25 2-Chlorothieno[3,2-d]pyrimidine
1119280-68-0
 $1.10 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
2-Chlorothieno[3,2-d]pyrimidine pictures 2020-01-09 2-Chlorothieno[3,2-d]pyrimidine
1119280-68-0
 $1.00 1KG 95-99% 1ton Career Henan Chemical Co

2-Chlorothieno[3,2-d]pyrimidine Spectrum

2-Chlorothieno[3,2-d]pyrimidine(1119280-68-0)1HNMR2-Chlorothieno[3,2-d]pyrimidine(1119280-68-0)1HNMR

1119280-68-0 (2-Chlorothieno[3,2-d]pyrimidine) Related Search:

2-Chlorothiophene-3-carboxylic acid Ethyl 2-chlorothiazole-5-carboxylate 2-Chloro-1,3-thiazole-4-carboxylic acid 2-Chloro-1,3-thiazole-5-carboxylic acid Methyl 2-chloro-4-thiazolecarboxylate
7-Bromo-2-chlorothieno[3,2-d]pyrimidine

1of2

2-Chlorothieno[3,2-d]pyrimidine Thieno[3,2-d]pyrimidine, 2-chloro- 2-Chlorothieno[3,2-d]pyrimidine ISO 9001：2015 REACH 1119280-68-0 Heterocycle-Pyrimidine series