5-Hydroxypyrazine-2-carboxylic acid methyl ester
- CAS No.
- 13924-95-3
- Chemical Name:
- 5-Hydroxypyrazine-2-carboxylic acid methyl ester
- Synonyms
- METHYL 5-HYDROXYPYRAZINE-2-CARBOXYLATE;methyl 5-oxo-4,5-dihydropyrazine-2-carboxylate;CBI-BB ZERO/008486;Methyl 5-hydropyrazine-2-carboxylate;methyl-5-hydroxy-2-pyrazinecarboxylate;methyl 6-oxo-1H-pyrazine-3-carboxylate;Methyl 5-hydroxypyrazine-2-carboxylate 95%;Methyl 5-oxo-4,5-dihydro-2-pyrazinecarboxylate;Methyl 4,5-dihydro-5-oxo-2-pyrazinecarboxylate;5-Hydrocy-pyrazine-2-carboxylic acid methyl ester
- CBNumber:
- CB7247194
- Molecular Formula:
- C6H6N2O3
- Molecular Weight:
- 154.12
- MDL Number:
- MFCD08273469
- MOL File:
- 13924-95-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H302+H312+H332-H315 |
| Precautionary statements | P280 |
| HS Code | 2933998090 |
5-Hydroxypyrazine-2-carboxylic acid methyl ester price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 63306 | METHYL 5-HYDROXYPYRAZINE-2-CARBOXYLATE 97% | 13924-95-3 | 5G | $37 | 2026-04-30 | Buy |
| AstaTech | 63306 | METHYL 5-HYDROXYPYRAZINE-2-CARBOXYLATE 97% | 13924-95-3 | 25G | $139 | 2026-04-30 | Buy |
| AstaTech | 63306 | METHYL 5-HYDROXYPYRAZINE-2-CARBOXYLATE 97% | 13924-95-3 | 100G | $574 | 2026-04-30 | Buy |
| Activate Scientific | AS30976 | Methyl 5-hydroxypyrazine-2-carboxylate 97% | 13924-95-3 | 1g | $27 | 2026-06-04 | Buy |
| Activate Scientific | AS30976 | Methyl 5-hydroxypyrazine-2-carboxylate 97% | 13924-95-3 | 5g | $60 | 2026-06-04 | Buy |
5-Hydroxypyrazine-2-carboxylic acid methyl ester Chemical Properties, Uses, Production
Uses
5-Hydroxypyrazine-2-carboxylic Acid Methyl Ester is a metabolite of Pyrazinamide (P840600), an antibacterial (tuberculostatic).
Synthesis
67-56-1
34604-60-9
13924-95-3
General procedure for the synthesis of methyl 5-hydroxypyrazine-2-carboxylate from methanol and 5-oxo-4,5-dihydropyrazine-2-carboxylic acid: Acetyl chloride (152 mL, 2.08 mol) was slowly added dropwise to methanol (5 L) at -20 °C. After the dropwise addition was completed, stirring was continued at this temperature for 30 minutes. Subsequently, 5-hydroxypyrazine-2-carboxylic acid (100 g, 714 mmol) was added and the mixture was heated to reflux and the reaction was maintained for 2 hours. Upon completion of the reaction, the solvent was removed by vacuum concentration and the residue was recrystallized from methanol (400 mL) to give 71 g (464 mmol) of methyl 5-hydroxypyrazine-2-carboxylate in 65% yield.
References
[1] Patent: WO2013/14567, 2013, A1. Location in patent: Page/Page column 80-81
[2] Patent: EP2239253, 2010, A1. Location in patent: Page/Page column 96
[3] Patent: EP1452525, 2004, A1. Location in patent: Page 15
5-Hydroxypyrazine-2-carboxylic acid methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chembon Pharmaceutical Co., Ltd. | 028-84252981 18583719936 | sales@chembon.com.cn | China | 854 | 64 |
| Shanghai Cuisen Pharmaceutical Technology Co., Ltd. | 13472757003 | yongnan.wang@cendrix.cn | China | 974 | 65 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Tongchuang Pharma(Suzhou). Co., Ltd. | 0512-63263366 18912765016 | tongtf110@sina.com | China | 984 | 62 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
| Shanghai yirong biology science and technology co., ltd | 18049974220 | 3060526242@qq.com | China | 999 | 60 |
| Kohn & Shawn Pharmatech Co.,Ltd | 0943-8293106 | sales@kyxpharma.com | China | 297 | 55 |
View Latest Price from 5-Hydroxypyrazine-2-carboxylic acid methyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 5-Hydroxypyrazine-2-carboxylic acid methyl ester
13924-95-3
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2020-04-30 | Methyl5-hydroxypyrazine-2-carboxylate
13924-95-3
|
1KG | 99.0%+ | 800 tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2019-09-02 | 5-Hydroxypyrazine-2-carboxylic acid methyl ester
13924-95-3
|
$7.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 5-Hydroxypyrazine-2-carboxylic acid methyl ester
13924-95-3
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- Methyl5-hydroxypyrazine-2-carboxylate
13924-95-3
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
-
- 5-Hydroxypyrazine-2-carboxylic acid methyl ester
13924-95-3
- $7.00
- 99%
- Career Henan Chemical Co
