1-Bromo-4-(bromomethyl)-2-methylbenzene
- CAS No.
- 27561-51-9
- Chemical Name:
- 1-Bromo-4-(bromomethyl)-2-methylbenzene
- Synonyms
- -2-methylbenzene;1-Bromo-4-(bromomethyl);4-bromo-3-methylbromobenzyl;4-Bromo-3-methylbenzylbromide;3-Methyl-4-bromobenzylbromide;1-bromo-4-(bromethyl)-2-methylbenzene;1-Bromo-4-(bromomethyl)-2-methylbenzene;Benzene, 1-bromo-4-(bromomethyl)-2-methyl-
- CBNumber:
- CB72498907
- Molecular Formula:
- C8H8Br2
- Molecular Weight:
- 263.96
- MDL Number:
- MFCD09909629
- MOL File:
- 27561-51-9.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H314 |
| Precautionary statements | P310-P260-P280 |
| HS Code | 2909309090 |
1-Bromo-4-(bromomethyl)-2-methylbenzene price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | CBA56151 | 1-Bromo-4-(bromomethyl)-2-methylbenzene | 27561-51-9 | 5g | $413 | 2026-06-04 | Buy |
| Activate Scientific | AS47795 | 1-Bromo-4-(bromomethyl)-2-methylbenzene 95% | 27561-51-9 | 1g | $71 | 2026-06-04 | Buy |
| Activate Scientific | AS47795 | 1-Bromo-4-(bromomethyl)-2-methylbenzene 95% | 27561-51-9 | 5g | $167 | 2026-06-04 | Buy |
| Apolloscientific | OR400670 | 4-Bromo-3-methylbenzyl bromide ≥95% | 27561-51-9 | 1g | $35 | 2026-06-04 | Buy |
| Activate Scientific | AS47795 | 1-Bromo-4-(bromomethyl)-2-methylbenzene 95% | 27561-51-9 | 25g | $498 | 2026-06-04 | Buy |
1-Bromo-4-(bromomethyl)-2-methylbenzene Chemical Properties, Uses, Production
Synthesis
149104-89-2
27561-51-9
Procedure for the synthesis of 1-bromo-4-(bromomethyl)-2-toluene: To a solution of 4-bromo-3-methylbenzyl alcohol (27.5 g, 136.8 mmol) in dichloromethane (250 mL) was added triphenylphosphine (39.4 g, 150.5 mmol) and carbon tetrabromide (49.9 g, 150.5 mmol) in sequence. The reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, water was added to quench the reaction. The organic layer was separated and dried over anhydrous sodium sulfate, followed by concentration under reduced pressure to remove the solvent. The crude product was purified by column chromatography to afford 1-bromo-4-(bromomethyl)-2-toluene (34 g, 94% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 7.94-7.92 (d, 1H), 7.70 (s, 1H), 7.53-7.51 (d, 1H), 4.86 (s, 2H), 2.83 (s, 3H).
References
[1] Patent: WO2015/42532, 2015, A1. Location in patent: Paragraph 0164
[2] Patent: US2011/82165, 2011, A1. Location in patent: Page/Page column 53
[3] Patent: WO2017/34994, 2017, A1. Location in patent: Page/Page column 38
[4] Macromolecules, 2013, vol. 46, # 21, p. 8500 - 8508
[5] Patent: WO2012/67664, 2012, A1. Location in patent: Page/Page column 45
1-Bromo-4-(bromomethyl)-2-methylbenzene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Changzhou Anxuan Chemical, Co., Ltd. | 13912302692 | sales@anxuanchem.com | China | 4824 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13774476675 | sales@fdc-chemical.com | China | 10000 | 58 |
