Abacavir 5’-Phosphate
- CAS No.
- 136470-77-4
- Chemical Name:
- Abacavir 5’-Phosphate
- Synonyms
- Abacavir Impurity 13;Abacavir 5'-Phosphate;Abacavir 5’-Phosphate;(1S-cis)-Abacavir Monophosphate;[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl dihydrogen phosphate;((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methyl dihydrogen phosphate;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, 1-(dihydrogen phosphate), (1S,4R)-;(1S,4R)- 4-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]-2-cyclopentene-1-Methanol Dihydrogen Phosphate (Ester)
- CBNumber:
- CB72502992
- Molecular Formula:
- C14H19N6O4P
- Molecular Weight:
- 366.31
- MDL Number:
- MFCD23160255
- MOL File:
- 136470-77-4.mol
| Melting point | 189-194°C (dec.) |
|---|---|
| Boiling point | 749.3±70.0 °C(Predicted) |
| Density | 1.93±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Methanol, Water |
| pka | 1.91±0.10(Predicted) |
| form | Solid |
| color | White |
| FDA UNII | 6I6AN9D95R |
Abacavir 5’-Phosphate price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 295325 | Abacavir 5'-phosphate Asreported | 136470-77-4 | 1mg | $698 | 2026-06-03 | Buy |
| Usbiological | 295325 | Abacavir 5'-phosphate Asreported | 136470-77-4 | 2mg | $1137 | 2026-06-03 | Buy |
| Usbiological | 295325 | Abacavir 5'-phosphate Asreported | 136470-77-4 | 5mg | $1878 | 2026-06-03 | Buy |
| Usbiological | 295325 | Abacavir 5'-phosphate Asreported | 136470-77-4 | 10mg | $3166 | 2026-06-03 | Buy |
| Usbiological | 001013 | Abacavir 5’-Phosphate | 136470-77-4 | 2.5mg | $496 | 2026-06-03 | Buy |
Abacavir 5’-Phosphate Chemical Properties, Uses, Production
Chemical Properties
White Solid
Uses
Abacavir 5’-Phosphate (Abacavir - In House Impurity) is a metabolite of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Definition
ChEBI: Abacavir monophosphate is the organic phosphate that is the 5'-monophosphate of abacavir. It has a role as a metabolite. It is a member of 2,6-diaminopurines and an organic phosphate. It is functionally related to an abacavir.
Abacavir 5’-Phosphate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9656 | 58 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| Shenzhen Botel Biotechnology Co. Ltd. | 13316949107 13316968096 | 1979313431@qq.com | China | 9619 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| NewCan Biotech Limited | +86-571-86912261 19975279805 | sales@newcanbio.com | China | 9984 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 029-81154043 17391733319 | 1086@dideu.com | China | 9970 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
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