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Abacavir 5’-Phosphate

CAS No.
136470-77-4
Chemical Name:
Abacavir 5’-Phosphate
Synonyms
Abacavir Impurity 13;Abacavir 5'-Phosphate;Abacavir 5’-Phosphate;(1S-cis)-Abacavir Monophosphate;[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl dihydrogen phosphate;((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methyl dihydrogen phosphate;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, 1-(dihydrogen phosphate), (1S,4R)-;(1S,4R)- 4-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]-2-cyclopentene-1-Methanol Dihydrogen Phosphate (Ester)
CBNumber:
CB72502992
Molecular Formula:
C14H19N6O4P
Molecular Weight:
366.31
MDL Number:
MFCD23160255
MOL File:
136470-77-4.mol
Last updated:2023-05-04 17:34:33
Product description Number Pack Size Price
Abacavir 5'-phosphate Asreported 295325 1mg $698
Abacavir 5'-phosphate Asreported 295325 2mg $1137
Abacavir 5'-phosphate Asreported 295325 5mg $1878
Abacavir 5'-phosphate Asreported 295325 10mg $3166
Abacavir 5’-Phosphate 001013 2.5mg $496
More product size

Abacavir 5’-Phosphate Properties

Melting point 189-194°C (dec.)
Boiling point 749.3±70.0 °C(Predicted)
Density 1.93±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Methanol, Water
pka 1.91±0.10(Predicted)
form Solid
color White
FDA UNII 6I6AN9D95R

Abacavir 5’-Phosphate price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 295325 Abacavir 5'-phosphate Asreported 136470-77-4 1mg $698 2026-06-03 Buy
Usbiological 295325 Abacavir 5'-phosphate Asreported 136470-77-4 2mg $1137 2026-06-03 Buy
Usbiological 295325 Abacavir 5'-phosphate Asreported 136470-77-4 5mg $1878 2026-06-03 Buy
Usbiological 295325 Abacavir 5'-phosphate Asreported 136470-77-4 10mg $3166 2026-06-03 Buy
Usbiological 001013 Abacavir 5’-Phosphate 136470-77-4 2.5mg $496 2026-06-03 Buy
Product number Packaging Price Buy
295325 1mg $698 Buy
295325 2mg $1137 Buy
295325 5mg $1878 Buy
295325 10mg $3166 Buy
001013 2.5mg $496 Buy

Abacavir 5’-Phosphate Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Abacavir 5’-Phosphate (Abacavir - In House Impurity) is a metabolite of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Definition

ChEBI: Abacavir monophosphate is the organic phosphate that is the 5'-monophosphate of abacavir. It has a role as a metabolite. It is a member of 2,6-diaminopurines and an organic phosphate. It is functionally related to an abacavir.

Abacavir 5’-Phosphate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 24)Suppliers
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BOC Sciences
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Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9679 58
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Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684; sales@rrkchem.com China 57422 58
Shenzhen Botel Biotechnology Co. Ltd. 13316949107 13316968096 1979313431@qq.com China 9591 58
Shaanxi Dideu Medichem Co. Ltd 029-81154043 17391733319 1086@dideu.com China 9987 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44910 58
[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl dihydrogen phosphate Abacavir 5’-Phosphate (1S,4R)- 4-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]-2-cyclopentene-1-Methanol Dihydrogen Phosphate (Ester) (1S-cis)-Abacavir Monophosphate ((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methyl dihydrogen phosphate 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, 1-(dihydrogen phosphate), (1S,4R)- Abacavir Impurity 13 Abacavir 5'-Phosphate 136470-77-4 C14H19N6O4P Bases & Related Reagents Intermediates & Fine Chemicals Metabolites & Impurities Nucleotides Pharmaceuticals Phosphorylating and Phosphitylating Agents