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2-(4-BROMOPHENYL)THIOPHENE

2-(4-BROMOPHENYL)THIOPHENE structure

CAS No.: 40133-22-0

Chemical Name:: 2-(4-BROMOPHENYL)THIOPHENE

Synonyms: 2-(4-BROMOPHENYL)THIOPHENE;2-(4-Bromophenyl)thiophene97%;1-Bromo-4-(thien-2-yl)benzene;Thiophene, 2-(4-bromophenyl)-;2-(4-Bromophenyl)thiophene 97%

CBNumber:: CB7250532

Molecular Formula:: C10H7BrS

Molecular Weight:: 239.13

MDL Number:: MFCD05664340

MOL File:: 40133-22-0.mol

MSDS File:: SDS

Last updated:2026-01-13 11:25:23

Product description	Number	Pack Size	Price
2-(4-Bromophenyl)thiophene 97%	596663	1g	$70
2-(4-Bromophenyl)thiophene >97.0%(GC)	B5106	1g	$154
2-(4-Bromophenyl)thiophene >97.0%(GC)	B5106	5g	$615
2-(4-Bromophenyl)thiophene	B687735	1g	$115
2-(4-Bromophenyl)thiophene	W9929	1g	$151

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2-(4-BROMOPHENYL)THIOPHENE Properties

Melting point	95-99 °C (lit.)
Boiling point	307.0±17.0 °C(Predicted)
Density	1.490±0.06 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
form	powder to crystal
color	White to Light yellow
InChI	1S/C10H7BrS/c11-9-5-3-8(4-6-9)10-2-1-7-12-10/h1-7H
InChIKey	XKOJJKOSNQXQGP-UHFFFAOYSA-N
SMILES	Brc1ccc(cc1)-c2cccs2
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H332-H335

Precautionary statements

P261-P280-P305+P351+P338

PPE

Eyeshields, Gloves, type N95 (US)

RIDADR

UN 3335

WGK Germany

Hazard Note

Harmful

HS Code

2934999090

Storage Class

11 - Combustible Solids

NFPA 704

	1
2		0

2-(4-BROMOPHENYL)THIOPHENE price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	596663	2-(4-Bromophenyl)thiophene 97%	40133-22-0	1g	$70	2023-01-07	Buy
TCI Chemical	B5106	2-(4-Bromophenyl)thiophene >97.0%(GC)	40133-22-0	1g	$154	2025-07-31	Buy
TCI Chemical	B5106	2-(4-Bromophenyl)thiophene >97.0%(GC)	40133-22-0	5g	$615	2025-07-31	Buy
TRC	B687735	2-(4-Bromophenyl)thiophene	40133-22-0	1g	$115	2021-12-16	Buy
AK Scientific	W9929	2-(4-Bromophenyl)thiophene	40133-22-0	1g	$151	2021-12-16	Buy

Product number	Packaging	Price	Buy
596663	1g	$70	Buy
B5106	1g	$154	Buy
B5106	5g	$615	Buy
B687735	1g	$115	Buy
W9929	1g	$151	Buy

2-(4-BROMOPHENYL)THIOPHENE Chemical Properties,Uses,Production

Uses

2-(4-Bromophenyl)thiophene is a reagent in the synthesis of 6-O-arylpropargyl diazalides, which has activity against Streptococcus pneumoniae.

Synthesis

589-87-7

193978-23-3

40133-22-0

General procedure for the synthesis of 2-(4-bromophenyl)thiophene from p-bromoiodobenzene and 2-thiophene boronic acid pinacol ester: 1-bromo-4-iodobenzene (2.0 g, 7.07 mmol), 4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane (2.97 g, 14.1 mmol), Pd(PPh3)4 ( 408 mg, 0.35 mmol) and Na2CO3 (1.49 g, 14.1 mmol) were dissolved in a solvent mixture of toluene (40 mL), THF (15 mL) and H2O (15 mL). The reaction mixture was heated to reflux. Upon completion of the reaction (monitored by TLC), the solvent was removed by distillation under reduced pressure, extracted by addition of H2O (30 mL) and CH2Cl2 (40 mL), the organic layer was separated and dried over anhydrous MgSO4. The crude product was purified by silica gel fast column chromatography to afford 2-(4-bromophenyl)thiophene (1.26 g, 74.6% yield). The spectral data of the obtained product were consistent with the values reported in the literature.1H NMR (400 MHz, CDCl3): δ 7.48 (d, J = 3.6 Hz, 4H), 7.29 (d, J = 4.4 Hz, 2H), 7.07 (dt, J = 1.4, 4.4 Hz, 1H).

References

[1] Journal of Nanoscience and Nanotechnology, 2016, vol. 16, # 1, p. 910 - 919
[2] ChemPlusChem, 2017, vol. 82, # 5, p. 742 - 749

2-(4-BROMOPHENYL)THIOPHENE Preparation Products And Raw materials

Raw materials

Sodium sulfate 18-Crown-6 Thiophene Sodium nitrite Fluoroboric acid

Potassium Acetate 4-Bromoaniline 1-Bromo-4-iodobenzene Thiophene-2-boronic acid pinacol ester Tetrahydrofuran

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Preparation Products

5-(4-BROMOPHENYL)THIOPHENE-2-CARBOXYLIC&

2-(4-BROMOPHENYL)THIOPHENE Suppliers

Global( 76)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 +86-18192627656	1059@dideu.com	China	3589	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49964	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
J & K SCIENTIFIC LTD.	18210857532; 18210857532	jkinfo@jkchemical.com	China	96815	76
Energy Chemical	021-021-58432009 400-005-6266	sales8178@energy-chemical.com	China	44802	61
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42934	64
Shandong Xiya Chemical Co., Ltd	13355009207 13355009207	3007715519@qq.com	China	18729	57

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
Alchem Pharmtech,Inc.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
GIHI CHEMICALS CO.,LIMITED	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
J & K SCIENTIFIC LTD.	76
Energy Chemical	61
Shanghai Hanhong Scientific Co.,Ltd.	64
Shandong Xiya Chemical Co., Ltd	57

View Lastest Price from 2-(4-BROMOPHENYL)THIOPHENE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-12-12	2-(4-BROMOPHENYL)THIOPHENE 40133-22-0	US $1.00-100.00 / KG	1KG	95%	300KG	Shaanxi Dideu Medichem Co. Ltd

2-(4-BROMOPHENYL)THIOPHENE
40133-22-0
US $1.00-100.00 / KG
95%
Shaanxi Dideu Medichem Co. Ltd

2-(4-BROMOPHENYL)THIOPHENE Spectrum

2-(4-BROMOPHENYL)THIOPHENE(40133-22-0)¹HNMR

40133-22-0(2-(4-BROMOPHENYL)THIOPHENE)Related Search:

2-(4-BROMOPHENYL)THIOPHENE ETHYL 2-AMINO-4-(4-BROMOPHENYL)THIOPHENE-3-CARBOXYLATE 4-(4-BROMOPHENYL)THIOPHENE-2-CARBOXYLIC 4-(4-BROMOPHENYL)THIOPHENE-2-CARBONYL CHLORIDE 6-(4-BROMO-PHENYL)-3H-THIENO[3,2-D]PYRIMIDIN-4-ONE

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5-(4-BROMOPHENYL)THIOPHENE-2-CARBOXYLIC ACID 5-(4-Bromophenyl)thiophene-2-carboxylic hydrazide 2-(2-Bromophenyl)thiophene 97%,2-(2-BROMOPHENYL)THIOPHENE 5-(4-BROMOPHENYL)THIOPHENE-2-CARBOXYLIC& Ethyl 2-amino-4-(3-bromophenyl)thiophene-3-carboxylate

4-(4-BROMOPHENYL)THIOPHENE-2-CARBOXYLIC ACID 5-(4-BROMOPHENYL)THIOPHENE-2-CARBOHYDRAZIDE,5-(4-BROMOPHENYL)THIOPHENE-2-CARBOXYLIC HYDRAZIDE Propyl 2-amino-4-(4-bromophenyl)thiophene-3-carboxylate

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2-(4-BROMOPHENYL)THIOPHENE 1-Bromo-4-(thien-2-yl)benzene 2-(4-Bromophenyl)thiophene97% 2-(4-Bromophenyl)thiophene 97% Thiophene, 2-(4-bromophenyl)- 40133-22-0 Thiophenes Heterocyclic Building Blocks Halogenated Heterocycles Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Thiophenes ThiophenesBuilding Blocks