3-bromo-2-methoxyaniline
- CAS No.
- 116557-46-1
- Chemical Name:
- 3-bromo-2-methoxyaniline
- Synonyms
- 3-Bromo-o-anisidine;2-amino-6-bromoanisole;3-BROMO-2-METHOXYANILINE;3-Bromo-2- methoxylaniline;3-Bromo-2-methoxybenzenamine;3-Bromo-2-methoxy-phenylamine;BenzenaMine, 3-broMo-2-Methoxy-;3-bromo-2-methoxyphenylamine hydrochloride;2-Amino-6-bromoanisole, 3-Bromo-o-anisidine
- CBNumber:
- CB72520161
- Molecular Formula:
- C7H8BrNO
- Molecular Weight:
- 202.05
- MDL Number:
- MFCD13186737
- MOL File:
- 116557-46-1.mol
- MSDS File:
- SDS
| Melting point | 65℃ |
|---|---|
| Boiling point | 268℃ |
| Density | 1.531 |
| refractive index | 1.5430 to 1.5470 |
| Flash point | 116℃ |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | clear liquid |
| pka | 3.46±0.10(Predicted) |
| color | Light yellow to Brown |
| InChI | InChI=1S/C7H8BrNO/c1-10-7-5(8)3-2-4-6(7)9/h2-4H,9H2,1H3 |
| InChIKey | ZLODWCIXZJMLJL-UHFFFAOYSA-N |
| SMILES | C1(N)=CC=CC(Br)=C1OC |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P280 | |||||||||
| RIDADR | UN 2810 6.1/PG III | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 2922290090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| NFPA 704 |
|
3-bromo-2-methoxyaniline price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS023930 | 3-Bromo-2-methoxyaniline | 50mg | $77.9 | 2026-04-30 | Buy | |
| TCI Chemical | B5131 | 3-Bromo-2-methoxyaniline >98.0%(GC)(T) | 116557-46-1 | 1g | $98 | 2026-04-30 | Buy |
| TCI Chemical | B5131 | 3-Bromo-2-methoxyaniline >98.0%(GC)(T) | 116557-46-1 | 5g | $329 | 2024-03-01 | Buy |
| Activate Scientific | AS48055 | 3-Bromo-2-methoxyaniline 98% | 116557-46-1 | 1g | $23 | 2026-06-04 | Buy |
| Activate Scientific | AS48055 | 3-Bromo-2-methoxyaniline 98% | 116557-46-1 | 5g | $51 | 2026-06-04 | Buy |
3-bromo-2-methoxyaniline Chemical Properties, Uses, Production
Synthesis
98775-19-0
116557-46-1
The general procedure for the synthesis of 3-bromo-2-methoxyaniline from 2-bromo-6-nitroanisole was as follows: 1-bromo-2-methoxy-3-nitrobenzene (20.1 g, 86.6 mmol) was heated to 80 °C with iron powder (33.4 g, 598 mmol) in a solvent mixture of acetic acid/water (1:1, 600 mL). After the reaction lasted for 1.5 h, the mixture was cooled to room temperature and filtered. The filtered solid was washed several times with ethyl acetate and water. The organic layers were combined, washed with saturated aqueous NaHCO3, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by column chromatography (eluent: petroleum ether/ethyl acetate = 20:1 to 10:1) to afford 3-bromo-2-methoxyaniline as a yellow solid (17.4 g, 99% yield).1H-NMR (300 MHz, DMSO-d6) δ (ppm): 3.66 (s, 3H), 5.23 (s, 2H), 6.64-6.76 (m, 1H). 3H).
References
[1] Patent: EP2987787, 2016, A1. Location in patent: Paragraph 0131
[2] Patent: WO2014/74661, 2014, A1. Location in patent: Paragraph 00173
[3] Patent: US2014/296229, 2014, A1. Location in patent: Paragraph 0258; 0259
[4] Patent: WO2014/154760, 2014, A1. Location in patent: Page/Page column 55-56
[5] Patent: WO2018/75937, 2018, A1. Location in patent: Paragraph 00487; 00495; 00496
3-bromo-2-methoxyaniline Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Vcare PharmaTech Co., Ltd. | 025-58741518 13327700685 | sales@vcarepharmatech.com | China | 281 | 61 |
| Anhui Sun-wise Pharmaceutical Co., Ltd. | 18856027890 18856027890 | 83618010@qq.com | China | 53 | 58 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16306 | 64 |
| NanTong Chemistar Chemical Co.,Ltd | 025-52643182 13914798241; | doria@chemipioneer.com.cn | China | 54 | 62 |
View Latest Price from 3-bromo-2-methoxyaniline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 3-bromo-2-methoxyaniline
116557-46-1
|
10kg | 99% | 10 tons | Qingdao RENAS Polymer Material Co., Ltd. | ||
 |
2026-08-08 | 2-amino-6-bromoanisole
116557-46-1
|
1kg | 99% | 500KG | Hangzhou ICH Biofarm Co., Ltd | ||
 |
2026-08-07 | 3-bromo-2-methoxyaniline
116557-46-1
|
$1.00-4.00 | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd |
-
- 3-bromo-2-methoxyaniline
116557-46-1
- $0.00
- 99%
- Qingdao RENAS Polymer Material Co., Ltd.
-
- 2-amino-6-bromoanisole
116557-46-1
- 99%
- Hangzhou ICH Biofarm Co., Ltd
-
- 3-bromo-2-methoxyaniline
116557-46-1
- $1.00-4.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
