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FMoc-NH-8(ethylene glycol)-acetic acid

FMoc-NH-8(ethylene glycol)-acetic acid structure

CAS No.: 868594-52-9

Chemical Name:: FMoc-NH-8(ethylene glycol)-acetic acid

Synonyms: FMoc-NH-PEG8-CH2COOH;Fmoc-NH-PEG8-CH2CO2H;Fmoc-PEG8-acetic acid;Fmoc-NH-PEG8-acetic Acid;Fmoc-N-Amido-PEG8-CH2COOH;Fmoc-N-amido-PEG8-acetic acid;Fmoc-NH-8(ethylene glycol)-actic acid;FMoc-NH-8(ethylene glycol)-acetic acid;FMoc-NH-8(ethylene glycol)-acetic acid ISO 9001：2015 REACH;26-[(9-Fluorenylmethoxycarbonyl)amino]-3,6,9,12,15,18,21,24-octaoxahexacosanoic acid

CBNumber:: CB72546851

Molecular Formula:: C33H47NO12

Molecular Weight:: 649.73

MDL Number:: MFCD27635163

MOL File:: 868594-52-9.mol

MSDS File:: SDS

Last updated:2026-07-16 07:06:08

Product description	Number	Pack Size	Price
Fmoc-NH-PEG8-CH2COOH	FF73057	100mg	$217
Fmoc-NH-PEG8-CH2COOH	FF73057	250mg	$407.5
Fmoc-NH-PEG8-CH2COOH	FF73057	500mg	$620
Fmoc-NH-PEG8-CH2COOH	FF73057	1000mg	$940
Fmoc-NH-PEG8-CH2COOH	FF73057	2000mg	$1300
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FMoc-NH-8(ethylene glycol)-acetic acid Properties

Boiling point	773.7±60.0 °C(Predicted)
Density	1.201±0.06 g/cm3(Predicted)
storage temp.	-20°C, protect from light
solubility	DMSO : 100 mg/mL (153.91 mM; Need ultrasonic)
form	Oil
pka	3.39±0.10(Predicted)
color	Light yellow to brown
InChIKey	JRLUSGRARXJCNA-UHFFFAOYSA-N
SMILES	C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCC(O)=O

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P280-P261
HS Code	2942000090

FMoc-NH-8(ethylene glycol)-acetic acid price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	FF73057	Fmoc-NH-PEG8-CH2COOH	868594-52-9	100mg	$217	2026-06-04	Buy
Biosynth	FF73057	Fmoc-NH-PEG8-CH2COOH	868594-52-9	250mg	$407.5	2026-06-04	Buy
Biosynth	FF73057	Fmoc-NH-PEG8-CH2COOH	868594-52-9	500mg	$620	2026-06-04	Buy
Biosynth	FF73057	Fmoc-NH-PEG8-CH2COOH	868594-52-9	1000mg	$940	2026-06-04	Buy
Biosynth	FF73057	Fmoc-NH-PEG8-CH2COOH	868594-52-9	2000mg	$1300	2026-06-04	Buy

Product number	Packaging	Price	Buy
FF73057	100mg	$217	Buy
FF73057	250mg	$407.5	Buy
FF73057	500mg	$620	Buy
FF73057	1000mg	$940	Buy
FF73057	2000mg	$1300	Buy

FMoc-NH-8(ethylene glycol)-acetic acid Chemical Properties,Uses,Production

Description

Fmoc-NH-PEG8-CH2COOH is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG8-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Cleavable Linker; PEGs; Alkyl/ether

References

[1] Michael A, et al. Synthesis of Bifunctional Integrin‐Binding Peptides Containing PEG Spacers of Defined Length for Non‐Viral Gene Delivery. Volume2008, Issue17.

FMoc-NH-8(ethylene glycol)-acetic acid synthesis

Synthesis of FMoc-NH-8(ethylene glycol)-acetic acid from tetraethylene glycol

FMoc-NH-8(ethylene glycol)-acetic acid Preparation Products And Raw materials

Raw materials

5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanoic acid, 28-hydroxy-,9H-fluoren-9-ylmethyl ester alpha-Azido-omega-hydroxy octa(ethylene glycol) 1-Azido-3,6,9-trioxaundecane-11-ol tetraethylene glycol

Preparation Products

FMoc-NH-8(ethylene glycol)-acetic acid Suppliers

Global( 113)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413	contact@trustwe.com	China	5742	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30203	58
XIAMEN SINOPEG BIOTECH CO., LTD.	+86-0592-7761068 15616186207	changaiwei@sinopeg.com	China	1133	58
Dideu Industries Group Limited	+8617392712697	1022@dideu.com	China	29095	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	38999	58
Changzhou AniKare Pharmatech Co., Ltd.	+86-0519-8359-8696	sales@anikare.com	China	9993	58
Aladdin Scientific		tp@aladdinsci.com	United States	50108	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53799	58
Chongqing jooe co., ltd	+86-15223382610	info@jooe.com	China	15950	58

Supplier	Advantage
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
XIAMEN SINOPEG BIOTECH CO., LTD.	58
Dideu Industries Group Limited	58
TargetMol Chemicals Inc.	58
Changzhou AniKare Pharmatech Co., Ltd.	58
Aladdin Scientific	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58
Chongqing jooe co., ltd	58

View Lastest Price from FMoc-NH-8(ethylene glycol)-acetic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-20	FMoc-NH-8(ethylene glycol)-acetic acid 868594-52-9	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2026-07-24	1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azatriacontan-30-oic acid 868594-52-9		1g	98%	1g/bottle, 10g/bottle, 100g/bottle	XIAMEN SINOPEG BIOTECH CO., LTD.
2026-07-15	Fmoc-NH-PEG8-CH2COOH 868594-52-9				10g	TargetMol Chemicals Inc.

FMoc-NH-8(ethylene glycol)-acetic acid
868594-52-9
$1.10
99.00%
Dideu Industries Group Limited

1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azatriacontan-30-oic acid
868594-52-9
98%
XIAMEN SINOPEG BIOTECH CO., LTD.

Fmoc-NH-PEG8-CH2COOH
868594-52-9
$0.00
TargetMol Chemicals Inc.

FMoc-NH-8(ethylene glycol)-acetic acid Spectrum

FMoc-NH-8(ethylene glycol)-acetic acid(868594-52-9)¹HNMR

868594-52-9(FMoc-NH-8(ethylene glycol)-acetic acid)Related Search:

Amino-PEG4-acid HS-PEG4-tBu Hexaethylene Glycol Monomethyl Ether H2N-PEG8-tBu 5,8,11,14-Tetraoxa-2-azahexadecanoic acid,16-amino-,1,1-dimethyl ester

2,5,8,11,14,17,20-Heptaoxadocosane-22-thiol Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) FMOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID Fmoc-N-amido-PEG11-acid Fmoc-N-amido-PEG17-acid

Fmoc-NH-PEG2-CH2CO2H FMoc-NH-5(ethylene glycol)-acetic acid Fmoc-NH-PEG3-CH2COOH Fmoc-N-amido-PEG15-acid 5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester

FMOC-18-AMINO-4,7,10,13,16-PENTAOXAOCTADECANOIC ACID Fmoc-N-amido-PEG14-acid FMoc-NH-PEG9-CH2CH2COOH

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FMoc-NH-8(ethylene glycol)-acetic acid FMoc-NH-PEG8-CH2COOH 5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester Fmoc-NH-PEG8-CH2CO2H Fmoc-PEG8-acetic acid Fmoc-NH-8(ethylene glycol)-actic acid FMoc-NH-8(ethylene glycol)-acetic acid ISO 9001：2015 REACH 26-[(9-Fluorenylmethoxycarbonyl)amino]-3,6,9,12,15,18,21,24-octaoxahexacosanoic acid 26-(fluoren-9-ylmethyloxycarbonylamino)-3,6,9,12,15,18,21,24-octaoxahexaeicosanoic acid Fmoc-N-Amido-PEG8-CH2COOH FmocNH-PEG8-CH2COOH/5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester 2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid Fmoc-N-amido-PEG8-acetic acid Fmoc-NH-PEG8-acetic Acid 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azatriacontan-30-oic acid 868594-52-9 peg