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Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI)

Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) structure

CAS No.: 127828-22-2

Chemical Name:: Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI)

Synonyms: t-Boc-Amido-PEG1-Amine;N-Boc-2-(2-Aminoethoxy)ethanamine;N-Boc-2-(2-amino-ethoxy)-ethylamine;BOC-NH-PEG1-NH2;NBoc-PEG1-Amine;Amino-PEG2-NH-Boc;Amino-PEGI-NH-Boc;BOC-N-AMIDO-PEG1-NH2;BocNH-PEG?-CH?CH?NH?;Boc-N-amido-PEG1-Amine

CBNumber:: CB71054537

Molecular Formula:: C9H20N2O3

Molecular Weight:: 204.27

MDL Number:: MFCD12031501

MOL File:: 127828-22-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-16 07:06:08

Product description	Number	Pack Size	Price
N-(tert-Butoxycarbonyl)-2-(2-aminoethoxy)ethylamine >98.0%(GC)(T)	B5683	200mg	$31
N-(tert-Butoxycarbonyl)-2-(2-aminoethoxy)ethylamine >98.0%(GC)(T)	B5683	1g	$92
BocNH-PEG1-CH2CH2NH2	FB72998	1g	$900
BocNH-PEG1-CH2CH2NH2	FB72998	0.5g	$900
BocNH-PEG1-CH2CH2NH2	FB72998	0.25g	$900
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Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) Properties

Boiling point	321.1±22.0 °C(Predicted)
Density	1.023±0.06 g/cm3(Predicted)
refractive index	1.4560 to 1.4600
storage temp.	2-8°C(protect from light)
pka	12.24±0.46(Predicted)
form	clear liquid
color	Colorless to Light orange to Yellow
InChI	InChI=1S/C9H20N2O3/c1-9(2,3)14-8(12)11-5-7-13-6-4-10/h4-7,10H2,1-3H3,(H,11,12)
InChIKey	VULKFBHOEKTQSF-UHFFFAOYSA-N
SMILES	C(OC(C)(C)C)(=O)NCCOCCN

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P310-P260-P280

HS Code

2934999090

NFPA 704

	1
0		0

Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) price More Price(74)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B5683	N-(tert-Butoxycarbonyl)-2-(2-aminoethoxy)ethylamine >98.0%(GC)(T)	127828-22-2	200mg	$31	2026-04-30	Buy
TCI Chemical	B5683	N-(tert-Butoxycarbonyl)-2-(2-aminoethoxy)ethylamine >98.0%(GC)(T)	127828-22-2	1g	$92	2026-04-30	Buy
Biosynth	FB72998	BocNH-PEG1-CH2CH2NH2	127828-22-2	1g	$900	2026-06-04	Buy
Biosynth	FB72998	BocNH-PEG1-CH2CH2NH2	127828-22-2	0.5g	$900	2026-06-04	Buy
Biosynth	FB72998	BocNH-PEG1-CH2CH2NH2	127828-22-2	0.25g	$900	2026-06-04	Buy

Product number	Packaging	Price	Buy
B5683	200mg	$31	Buy
B5683	1g	$92	Buy
FB72998	1g	$900	Buy
FB72998	0.5g	$900	Buy
FB72998	0.25g	$900	Buy

Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Uses,Production

Description

t-Boc-N-Amido-PEG1-amine is a small molecule PEG reagent containing an amino group and Boc-protected amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Properties

Colorless viscous liquid

Uses

Amino-PEG2-NH-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Synthesis

Carbamic acid, N-[2-(2-azidoethoxy)ethyl]-, 1,1-dimethylethyl ester

176220-30-7

Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI)

127828-22-2

Step 4: Synthesis of tert-butyl [2-(2-aminoethoxy)ethyl]carbamate (58) Under argon protection, tert-butyl (2-(2-azidoethoxy)ethyl)carbamate (57, 5.0 g, 0.0217 mol) was dissolved in methanol (100 mL) and palladium/carbon catalyst (2.5 g, 10 mL) was added. The reaction mixture was stirred overnight at room temperature under hydrogen (50 psi) atmosphere. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad and the filtrate was concentrated under reduced pressure to afford tert-butyl [2-(2-aminoethoxy)ethyl]carbamate (58, 3.0 g). The resulting product can be used directly in the subsequent reaction without further purification. 1H NMR (400 MHz, MeOD) δ 3.48-3.45 (m, 4H), 3.23-3.20 (t, 2H), 2.77-2.75 (m, 2H), 1.43 (s, 9H).

IC 50

PEGs; Alkyl/ether

References

[1] Qiu X, et al. Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Org Lett. 2019 May 17;21(10):3838-3841. DOI:10.1021/acs.orglett.9b01326

Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) synthesis

Synthesis of Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) from 1,5-DIAMINO-3-OXAPENTANE and Di-tert-butyl dicarbonate

Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials

Raw materials

Carbamic acid, N-[2-(2-azidoethoxy)ethyl]-, 1,1-dimethylethyl ester 2,2'-OXYBIS(ETHYLAMINE) DIHYDROCHLORIDE 1,5-DIAMINO-3-OXAPENTANE t-Boc-N-Amido-PEG2-Ms 2-(2-BOC-AMINOETHOXY)ETHANOL

Di-tert-butyl dicarbonate Activated carbon Hydrogen Methanol Palladium

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Preparation Products

Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) Suppliers

Global( 156)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
Fuxin Pharmaceutical	+86-021-021-50872116	contact@fuxinpharm.com	China	9976	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413	contact@trustwe.com	China	5742	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1059@dideu.com	China	29096	58
Baoji Guokang Healthchem Co., Ltd.	+86-0917-3909592 +86-13892490616	gksales1@gk-bio.com	China	9037	58
CD Chemical Group Limited	+86-13651442114	info@codchem.com	China	17253	58
changzhou huayang technology co., ltd	+8615250961469	2571773637@qq.com	China	9628	58
Alfa Chemistry	+1-5166625404;	Info@alfa-chemistry.com	United States	20000	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	38999	58

Supplier	Advantage
career henan chemical co	58
Fuxin Pharmaceutical	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
TargetMol Chemicals Inc.	58
Dideu Industries Group Limited	58
Baoji Guokang Healthchem Co., Ltd.	58
CD Chemical Group Limited	58
changzhou huayang technology co., ltd	58
Alfa Chemistry	58
TargetMol Chemicals Inc.	58

View Lastest Price from Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-15	Amino-PEG2-NH-Boc 127828-22-2				10g	TargetMol Chemicals Inc.
2026-01-28	BocNH-PEG1-CH2CH2NH2 127828-22-2		1kg	98%	200kg	LAURENT
2021-07-13	Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) 127828-22-2	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

Amino-PEG2-NH-Boc
127828-22-2
$0.00
TargetMol Chemicals Inc.

BocNH-PEG1-CH2CH2NH2
127828-22-2
98%
LAURENT

Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI)
127828-22-2
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) Spectrum

Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI)(127828-22-2)¹HNMR

127828-22-2(Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI))Related Search:

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Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) CarbaMic acid, [2-(2-aMinoethoxy)ethyl]-, 1,1-diMethylethyl ester 3-Oxapentane-1,5-diamine, N-BOC protected, 2-(2-Aminoethoxy)ethylamine, N-BOC protected tert-Butyl [2-(2-aminoethoxy)ethyl]carbamate N-Boc-2-(2-Aminoethoxy)ethanamine N-Boc-2-aminoethyl 2-aminoethyl ether BocNH-PEG₁-CH₂CH₂NH₂ N-Boc-2-(2-amino-ethoxy)-ethylamine t-Boc-N-amido-PEG1-Amine N-Boc-2-(2-aminoethoxy)ethylamine≥ 98% (GC) tert-butyl N-[2-(2-aminoethoxy)ethyl]carbamate BOC-N-AMIDO-PEG1-NH2 BOC-NH-PEG1-NH2 N-(tert-Butoxycarbonyl)-2-(2-aminoethoxy)ethylamine [2-(2-aMinoethoxy)ethyl]-, 1,1-diMethylethyl ester Boc-N-amido-PEG1-Amine Boc-NH-PEG2 Tert-butyl 2-(2-aminoethoxy)ethylcarbamate [2-(2-Aminoethoxy)ethyl]carbamic Acid tert-Butyl Ester Amino-PEG2-NH-Boc Carbamic acid, N-[2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) USP/EP/BP [2-(2-aminoethoxy)ethyl]- BocNH-PEG?-CH?CH?NH? Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ... N-Boc-2-(2-amino-ethoxy)-ethyla NBoc-PEG1-Amine t-Boc-Amido-PEG2-Amine N-[2-(2-Aminoethoxy)ethyl]carbamic acid tert-butyl ester Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethyl Amino-PEGI-NH-Boc t-Boc-Amido-PEG1-Amine 127828-22-2 N-BOC peg