N-Methoxy-N,2-dimethylpropanamide
- CAS No.
- 113778-69-1
- Chemical Name:
- N-Methoxy-N,2-dimethylpropanamide
- Synonyms
- N-Methoxy-N-MethylisobutyraMide;N-Methoxy-N,2-dimethylpropanamide;Propanamide, N-methoxy-N,2-dimethyl-;N-Methoxy-2-methyl-N-methylpropanamide;N-METHOXY-N,2-DIMETHYLPROPANAMIDE(WX619185)
- CBNumber:
- CB72565294
- Molecular Formula:
- C6H13NO2
- Molecular Weight:
- 131.17
- MDL Number:
- MFCD11847606
- MOL File:
- 113778-69-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H302+H312+H332-H315 |
| Precautionary statements | P280-P301+P312-P362+P364 |
| HS Code | 2928009090 |
N-Methoxy-N,2-dimethylpropanamide price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 459314 | N-Methoxy-N-methylisobutyramide | 113778-69-1 | 2.5g | $468 | 2026-06-03 | Buy |
| Usbiological | 459314 | N-Methoxy-N-methylisobutyramide | 113778-69-1 | 5g | $814 | 2026-06-03 | Buy |
| Apolloscientific | OR959864 | N-Methoxy-N,2-dimethylpropanamide 98% | 113778-69-1 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR959864 | N-Methoxy-N,2-dimethylpropanamide 98% | 113778-69-1 | 5g | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR959864 | N-Methoxy-N,2-dimethylpropanamide 98% | 113778-69-1 | 25g | $66 | 2026-06-04 | Buy |
N-Methoxy-N,2-dimethylpropanamide Chemical Properties, Uses, Production
Uses
N-Methoxy-N-methylisobutyramide is an intermediate in the synthesis of pteridine derivatives with potential protective effects with vibrio cholerae infection.
Synthesis
6638-79-5
79-30-1
113778-69-1
I. Synthesis of N-methoxy-N,2-dimethylpropionamide. Isobutyryl chloride (6.02 mL, 57.5 mmol) was added slowly and dropwise to a solution of N,O-dimethylhydroxylamine hydrochloride (5.61 g, 57.5 mmol) and triethylamine (17.6 mL, 126.5 mmol) in dichloromethane (100 mL). The reaction mixture was stirred at room temperature overnight. After completion of the reaction, the reaction mixture was washed with deionized water (100 mL) and the organic layer was dried with anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure and the crude product was purified by silica gel column chromatography (eluent: n-hexane to 9:1 n-hexane/ethyl acetate) to afford N-methoxy-N,2-dimethylpropanamide (5.55 g, 74% yield).1H NMR (300 MHz, DMSO-d6) δ 3.72 (s, 3H), 3.31 (m, 1H), 3.18 (s, 3H) 1.09 (d, J = 6.87 Hz, 6H).
References
[1] Organic Letters, 2012, vol. 14, # 9, p. 2250 - 2253
[2] Journal of Medicinal Chemistry, 2015, vol. 58, # 7, p. 3117 - 3130
[3] Journal of Medicinal Chemistry, 2017, vol. 60, # 12, p. 4840 - 4860
[4] Chemistry - A European Journal, 2017, vol. 23, # 57, p. 14345 - 14357
[5] Organic and Biomolecular Chemistry, 2013, vol. 11, # 20, p. 3337 - 3340
N-Methoxy-N,2-dimethylpropanamide Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
N-Methoxy-N,2-dimethylpropanamide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Z IntellecChem & Tech. Co., Ltd | 13179383568; 15050866711 | contact@zintellec.com | China | 317 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Sci General Material & Chemical Ltd | 021-58388037;21-58388037 13472507714 | 35177634@qq.com;1589045147@qq.com | China | 795 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
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| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
View Latest Price from N-Methoxy-N,2-dimethylpropanamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-16 | N-Methoxy-N,2-dimethylpropanamide
113778-69-1
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd |
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- N-Methoxy-N,2-dimethylpropanamide
113778-69-1
- 98%
- Shaanxi Dideu New Materials Co. Ltd
