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N-Methylpropionamide

N-Methylpropionamide structure

CAS No.: 1187-58-2

Chemical Name:: N-Methylpropionamide

Synonyms: Propanamide, N-methyl-;N-Methylpropanamide;N-Methylpropiomide;n-methyl-propanamid;N-methylpropylamide;n-methyl-propionamid;N-methyl-Propanamide;N-METHYLPROPIONAMIDE;N-Methylpropionamide>Propionamide, N-methyl-

CBNumber:: CB7468599

Molecular Formula:: C4H9NO

Molecular Weight:: 87.12

MDL Number:: MFCD00009300

MOL File:: 1187-58-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-06-23 16:59:16

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N-Methylpropionamide Properties

Melting point	-43 °C (lit.)
Boiling point	146 °C/90 mmHg (lit.)
Density	0.931 g/mL at 25 °C (lit.)
refractive index	n20/D 1.436(lit.)
Flash point	222 °F
storage temp.	Store at room temperature
pka	16.61±0.46(Predicted)
form	clear liquid
color	Colorless
Specific Gravity	0.93
Specific Heat Capacity	Cp(liquid): 2.05 J/(g·K), at 25℃
BRN	1737640
InChI	1S/C4H9NO/c1-3-4(6)5-2/h3H2,1-2H3,(H,5,6)
InChIKey	QJQAMHYHNCADNR-UHFFFAOYSA-N
SMILES	CCC(=O)NC
CAS DataBase Reference	1187-58-2(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	2TSZ8HW6DQ
NIST Chemistry Reference	Propanamide, N-methyl-(1187-58-2)
EPA Substance Registry System	Propanamide, N-methyl- (1187-58-2)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

target organs

Respiratory system

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

RTECS

UE4515000

TSCA

TSCA listed

HS Code

2924.19.8000

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

N-Methylpropionamide price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	290874	N-Methylpropionamide 98%	1187-58-2	5g	$75.1	2023-01-07	Buy
TCI Chemical	M0488	N-Methylpropionamide >99.0%(GC)	1187-58-2	5mL	$68	2026-04-30	Buy
TCI Chemical	M0488	N-Methylpropionamide >99.0%(GC)	1187-58-2	25mL	$198	2026-04-30	Buy
Apolloscientific	OR937813	N-Methylpropionamide >98%	1187-58-2	5g	$21	2026-06-04	Buy
Apolloscientific	OR937813	N-Methylpropionamide >98%	1187-58-2	25g	$75	2026-06-04	Buy

Product number	Packaging	Price	Buy
290874	5g	$75.1	Buy
M0488	5mL	$68	Buy
M0488	25mL	$198	Buy
OR937813	5g	$21	Buy
OR937813	25g	$75	Buy

N-Methylpropionamide Chemical Properties, Uses, Production

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

N-Methylpropionamide has been used to investigate amide-induced phase separation of hexafluoro-2-propanol-water mixtures.

Purification Methods

The amide is a colourless, odourless, neutral liquid at room temperature with a high dielectric constant. The amount of water present can be determined directly by Karl Fischer titration, GLC and NMR have been used to detect unreacted propionic acid. Commercial material of high quality is available, probably from the condensation of anhydrous methylamine with 50% excess of propionic acid. Rapid heating to 120-140o with stirring favours the reaction by removing water either directly or as the ternary xylene azeotrope. The quality of the distillate improves during the distillation. N-Methylpropionamide can be dried over CaO. Water and unreacted propionic acid are removed as their xylene azeotropes. It is then distilled in a vacuum. Material used as an electrolyte solvent (specific conductance less than 10-6 ohm-1 cm -1) is obtained by fractional distillation under reduced pressure, and storage over BaO or molecular sieves because it readily absorbs moisture from the atmosphere on prolonged storage. [Hoover Pure Appl Chem 37 581 1974, Recommended Methods for Purification of Solvents and Tests for Impurities, Coetzee Ed., Pergamon Press, 1982, Beilstein 4 IV 183.]

N-Methylpropionamide Preparation Products And Raw materials

Raw materials

Preparation Products

1-Propanamine, N-methyl-, hydrochloride

N-Methylpropionamide Suppliers

Global Suppliers ( 156)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Shanghai Longsheng chemical Co.,Ltd.	58099637 13585536065	sales@shlschem.com	China	9880	59
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
China Langchem Inc.	0086-21-58956006		China	7798	57
RYSS TECH LTD	400-188-0725 +86 21 34310725 13611771617		China	1999	57
Maya High Purity Chemicals	+86 (573) 82222445 (0)18006601000 452520369	sales@maya-r.com	China	11693	57
TOKYO CHEMICAL INDUSTRY CO., LTD.	03-36680489	Sales-JP@TCIchemicals.com	Japan	28364	80
TCI Europe	320-37350700	sales@tcieurope.eu	Europe	23654	75
TCI AMERICA	800-4238616	sales@tciamerica.com	Americas	23636	75

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
TCI (Shanghai) Development Co., Ltd.	81
Shanghai Longsheng chemical Co.,Ltd.	59
Shanghai Hanhong Scientific Co.,Ltd.	64
China Langchem Inc.	57
RYSS TECH LTD	57
Maya High Purity Chemicals	57
TOKYO CHEMICAL INDUSTRY CO., LTD.	80
TCI Europe	75
TCI AMERICA	75

View Latest Price from N-Methylpropionamide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-10-13	N-Methylpropionamide 1187-58-2		1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-09-02	N-Methylpropionamide 1187-58-2	$1.30-32.00	1kg	99%		Henan Fengda Chemical Co., Ltd
2020-02-01	N-Methylpropanamide 1187-58-2	$1.00	1KG	Min98% HPLC		Career Henan Chemical Co

N-Methylpropionamide
1187-58-2
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

N-Methylpropionamide
1187-58-2
$1.30-32.00
99%
Henan Fengda Chemical Co., Ltd

N-Methylpropanamide
1187-58-2
$1.00
Min98% HPLC
Career Henan Chemical Co

N-Methylpropionamide Spectrum

N-Methylpropionamide(1187-58-2)MS N-Methylpropionamide(1187-58-2)¹HNMR N-Methylpropionamide(1187-58-2)¹³CNMR N-Methylpropionamide(1187-58-2)IR1 N-Methylpropionamide(1187-58-2)Raman

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