ChemicalBook >> CAS DataBase List >>9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine
9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine
- CAS No.
- 97845-60-8
- Chemical Name:
- 9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine
- Synonyms
- 9-(4-ACETOXY-3-ACETOXYMETHYLBUT-1-YL)-2-AMINO-6-CHLOROPURINE;PT-11;9-(4-Acetoxy-3-aceto;Penciclovir Impurity E;Famciclovir Impurity 15;Fanciclovir USP Impurity M;Famciclovir 6-Chloro Impurity;6-Chloro Famciclovir Impurity;The interMediate of FaMciclovir;Famciclovir 6-Chloro Impurity (USP)
- CBNumber:
- CB7260409
- Molecular Formula:
- C14H18ClN5O4
- Molecular Weight:
- 355.78
- MDL Number:
- MFCD08458206
- MOL File:
- 97845-60-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 04:58:24
| Melting point | 132-134 °C(Solv: isopropanol (67-63-0)) |
|---|---|
| Boiling point | 575.0±60.0 °C(Predicted) |
| Density | 1.49±0.1 g/cm3(Predicted) |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 2.23±0.10(Predicted) |
| color | Off-White to Light Yellow |
| Major Application | pharmaceutical small molecule |
| InChI | InChI=1S/C14H18ClN5O4/c1-8(21)23-5-10(6-24-9(2)22)3-4-20-7-17-11-12(15)18-14(16)19-13(11)20/h7,10H,3-6H2,1-2H3,(H2,16,18,19) |
| InChIKey | KXPSHSVVYGZKAV-UHFFFAOYSA-N |
| SMILES | C(OC(=O)C)C(CCN1C2C(N=C1)=C(Cl)N=C(N)N=2)COC(=O)C |
| LogP | 0.92 at 25℃ and pH9.1 |
| CAS DataBase Reference | 97845-60-8(CAS DataBase Reference) |
| FDA UNII | V9DM57H0B7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| REACH Registrations | Inactive |
9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-A164140-1G | 9-[4-Acetoxy-3-(acetoxymethyl)butyl]-2-amino-6-chloropurine | 97845-60-8 | 1g | $258 | 2026-06-03 | Buy |
| TRC | TRC-A164140-10G | 9-[4-Acetoxy-3-(acetoxymethyl)butyl]-2-amino-6-chloropurine | 97845-60-8 | 10g | $1433 | 2026-06-03 | Buy |
| Matrix Scientific | 091947 | 2-(2-(2-Amino-6-chloro-9H-purin-9-yl)-ethyl)propane-1,3-diyl diacetate | 97845-60-8 | 25.00g | $45 | 2026-05-18 | Buy |
| Matrix Scientific | 091947 | 2-(2-(2-Amino-6-chloro-9H-purin-9-yl)-ethyl)propane-1,3-diyl diacetate | 97845-60-8 | 100.00g | $148 | 2026-05-18 | Buy |
| aablocks | AA00H7BC | 2-Amino-6-chloro-9-(4-acetoxy-3-acetoxymethylbutyl)purine 98% | 97845-60-8 | 1g | $10 | 2026-05-28 | Buy |
9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine Chemical Properties, Uses, Production
Uses
9-[4-Acetoxy-3-(acetoxymethyl)butyl]-2-amino-6-chloropurine is an impurity of Famciclovir (F101125), an antiviral agent and a prodrug of Penciclovir (P221500).
Synthesis
9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine through a four-step synthesis: steps. 1) Preparation of 1,3-diacetoxy-2-bromopropane: 1,3-Dichloro-2-propanol reacts with potassium acetate and ammonium chloride in DMF. After work-up and reaction with triethylamine hydrobromide, distillation yields the product. 2) Preparation of the zinc reagent: 1,3-Diacetoxy-2-bromopropane reacts with zinc powder and anhydrous lithium bromide in THF, initiated by TMSCl. 3) Preparation of the catalyst: Palladium acetate and S-Phos are stirred in THF under nitrogen. 4) Preparation of the final product: 2-Amino-6-chloro-9-bromoethylpurine, the freshly prepared catalyst, and the zinc reagent react in THF. Work-up and recrystallization from ethanol yield the product.
9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 176)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD. | 21-33585366 13311639313 | sales@shyrchem.com | China | 807 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Beijing Lunarsun Pharmaceutical Co.,LTD. | 86-10-64911848-8020.8010 | sales@lunarsun.com.cn | China | 95 | 60 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6744 | 52 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 |
View Latest Price from 9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-08 | 9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine
97845-60-8
|
1kg | 99.0%min | 10tons | Hangzhou ICH Biofarm Co., Ltd | ||
 |
2019-07-06 | 9-(4-acetoxy-3-acetoxymethylbutyl)-2-Amino-6-chloropurine
97845-60-8
|
$1.00 | 1KG | 98% | 100kg | Career Henan Chemical Co | |
 |
2018-10-22 | 9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine
97845-60-8
|
$1.00 | 1KG | 98% | 20tons | Shanghai Yingrui Biopharma Co., Ltd. |
-
- 9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine
97845-60-8
- 99.0%min
- Hangzhou ICH Biofarm Co., Ltd
-
- 9-(4-acetoxy-3-acetoxymethylbutyl)-2-Amino-6-chloropurine
97845-60-8
- $1.00
- 98%
- Career Henan Chemical Co
-
- 9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine
97845-60-8
- $1.00
- 98%
- Shanghai Yingrui Biopharma Co., Ltd.
97845-60-8 (9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine) Related Search:
Glycine
Aminoethoxyvinyl glycine hydrochloride
1,3-Propanediol, 2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]-
9-(4-hydroxybutyl)guanine
Famciclovir Impurity 7
1of4
9-[4-Acetoxy-3-(acetoxymethyl)butyl]-2-amino-6-chl
9-(4-ACETOXY-3-ACETOXYMETHYLBUT-1-YL)-2-AMINO-6-CHLOROPUINE
9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine
1,3-Propanediol,2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]diacetate(ester)(9Cl
9-(4-Acetoxy-3-aceto
2-(2-(2-AMino-6-chloro-9H-purin-9-yl)ethyl)propane-1,3-diyl diacetate
9-(4-ACETOXY-3)-ACETOXYMETHYLBURYL-2-AMINO-6-CHLOROPURINE
1,3-Propanediol,2-[2-(2-aMino-6-chloro-9H-purin-9-yl)ethyl]diacetate(ester)
The interMediate of FaMciclovir
Famciclovir 6-Chloro Impurity (USP)
1,3-propanediol,2-[2-(2-amino-6-chloro-9H-purin-9-yl)]-1,3-diacetate
9- (4- acetyl -3- acetyl acetyl acetyl oxygen) -2- amino -6- chloride
[2-(acetyloxymethyl)-4-(2-amino-6-chloropurin-9-yl)butyl] acetate
Famciclovir Impurity 15
Famciclovir 6-Chloro Impurity
2-[2-(2-Amino-6-chloro-9H-purin-9-yl)ethyl]-1,3-propanediol 1,3-Diacetate
9-[4-Acetoxy-3-(acetoxymethyl)butyl
1,3-Propanediol, 2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]-, 1,3-diacetate
Fanciclovir USP Impurity M
Famciclovir 6-Chloro Impurity (USP) / Penciclovir Impurity E
Penciclovir Impurity E
6-Chloro Famciclovir Impurity
1,3-Propanediol,2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]d...
1,1'-[2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]-1,3-propanediyl] diacetate
PT-11
9-(4-ACETOXY-3-ACETOXYMETHYLBUT-1-YL)-2-AMINO-6-CHLOROPURINE
209-(4-acetoxy-3-acetoxy-MethylButyl)-2-amino-6-Chloropurine
97845-60-8
C14H18N5O4Cl
C14H18ClN5O4
API intermediates
