MK-2206
- CAS No.
- 1032349-93-1
- Chemical Name:
- MK-2206
- Synonyms
- MK-2206(FREE BASE);Benodanil Impurity 8;8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-ol;1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-
- CBNumber:
- CB72628146
- Molecular Formula:
- C25H21N5O
- Molecular Weight:
- 407.47
- MDL Number:
- MFCD12912151
- MOL File:
- 1032349-93-1.mol
- MSDS File:
- SDS
| FDA UNII | 51HZG6MP1K |
|---|
MK-2206 Chemical Properties, Uses, Production
Uses
A highly selective inhibitor of Akt. Akt1, IC50=8 nM; Akt2, IC50=12 nM; Akt3, IC50=65 nM.
Definition
ChEBI: MK-2206 is an organic heterotricyclic compound that is [1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one substituted at positions 8 and 9 respectively by 4-(1-aminocyclobutyl)phenyl and phenyl groups. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It is functionally related to a 1,6-naphthyridine.
IC 50
Akt1: 8 nM (IC50); Akt2: 12 nM (IC50); Akt3: 65 nM (IC50)
MK-2206 Preparation Products And Raw materials
Raw materials
Preparation Products
MK-2206 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Trio PharmaTech Co., Ltd. | 0531-88811783 | sales@trio-pharmatech.com | China | 1856 | 62 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| NCE Biomedical Co.,Ltd. | 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 | China | 1490 | 55 | |
| Shanghai Witofly Chemical Co.,Ltd | sales@witofly.com | China | 2853 | 52 | |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2374 | 58 |
| Hui Chem Co., Ltd. | 021-34799779 18918539052 | 1879902218@qq.com | China | 77 | 55 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9239 | 55 | |
| Tcichem, Inc. | 13918644899 | 81587635@qq.com | China | 1994 | 55 |
| Lanzhou Angeli Biochemical Technology Co., Ltd. | 0931-8235634 13321316780 | 1455540579@qq.com | China | 957 | 55 |
View Latest Price from MK-2206 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-07-27 | MK-2206 free base
1032349-93-1
|
10g | TargetMol Chemicals Inc. |
-

- MK-2206 free base
1032349-93-1
- TargetMol Chemicals Inc.




