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Colby trifluoromethylation reagent

CAS No.
1400691-55-5
Chemical Name:
Colby trifluoromethylation reagent
Synonyms
Colby trifluoromethylation reagent;Hexafluoroacetone hydrate-1,8-diazo-bicyclo[5.4.0]undec-7-ene salt;Hexafluoroacetone hydrate-1,8-diazo-bicyclo[5.4.0]undec-7-ene salt AldrichCPR;1,1,1,3,3,3-Hexafluoropropane-2,2-diol-1,8-diazo-bicyclo[5.4.0]undec-7-ene salt
CBNumber:
CB72750401
Molecular Formula:
C12H18F6N2O2
Molecular Weight:
336.28
MDL Number:
MFCD22417241
MOL File:
1400691-55-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:58:20

Colby trifluoromethylation reagent Properties

form solid
SMILES OC([O-])(C(F)(F)F)C(F)(F)F.C1CCC2=[N+](CC1)CCCN2
UNSPSC Code 12352101

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H318
Precautionary statements  P280-P301+P312+P330-P305+P351+P338+P310
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1

Colby trifluoromethylation reagent price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 803774 Colby trifluoromethylation reagent 1400691-55-5 1g $55.4 2023-06-20 Buy
Sigma-Aldrich 803774 Colby trifluoromethylation reagent 1400691-55-5 10g $342 2023-06-20 Buy
Chem-Impex 47396 Colby trifluoromethylation reagent ≥95% 1400691-55-5 1G $50 2026-05-19 Buy
Chem-Impex 47396 Colby trifluoromethylation reagent ≥95% 1400691-55-5 5G $230 2026-05-19 Buy
aablocks AA009ZUH 1,1,1,3,3,3-Hexafluoro-2,2-propanediol 2,3,4,6,7,8,9,10-octahydropyrimido[1,2-a]azepine 98% 1400691-55-5 1g $48 2026-05-28 Buy
Product number Packaging Price Buy
803774 1g $55.4 Buy
803774 10g $342 Buy
47396 1G $50 Buy
47396 5G $230 Buy
AA009ZUH 1g $48 Buy

Colby trifluoromethylation reagent Chemical Properties, Uses, Production

Uses

The Colby Trifluoromethylation Reagent is an air-stable, white solid, which can be used as a source of fluoroform through the release of trifluoroacetate. This reagent can add trifluoromethyl groups in a nucleophlic fashion to carbonyls and sulfides.

General Description

Colby trifluoromethylation reagent is an amidinate salt of hexafluoroacetone hydrate. This reagent can be prepared from the ethereal solution of hexafluoroacetone trihydrate. It undergoes various trifluoromethylation reactions with electrophiles under different reaction conditions to afford trifluoromethylated products.

Colby trifluoromethylation reagent Preparation Products And Raw materials

Colby trifluoromethylation reagent Suppliers

Global Suppliers ( 6)
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. 025-66061636 19370895928 qqyang@aikonchem.com China 9995 58
Colby trifluoromethylation reagent Hexafluoroacetone hydrate-1,8-diazo-bicyclo[5.4.0]undec-7-ene salt Hexafluoroacetone hydrate-1,8-diazo-bicyclo[5.4.0]undec-7-ene salt AldrichCPR 1,1,1,3,3,3-Hexafluoropropane-2,2-diol-1,8-diazo-bicyclo[5.4.0]undec-7-ene salt 1400691-55-5