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RES-701-1

CAS No.
151308-34-8
Chemical Name:
RES-701-1
Synonyms
RES-701-1;RES-701-1 USP/EP/BP;cyclo(gly-asn-trp-his-gly-thr-ala-pro-*B-asp)-thr;GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP;GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH;CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH;CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP;CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH;L-Tryptophan, glycyl-L-asparaginyl-L-tryptophyl-L-histidylglycyl-L-threonyl-L-alanyl-L-prolyl-L-α-aspartyl-L-tryptophyl-L-phenylalanyl-L-phenylalanyl-L-asparaginyl-L-tyrosyl-L-tyrosyl-, (9→1)-lactam
CBNumber:
CB7301326
Molecular Formula:
C103H115N23O23
Molecular Weight:
2043.16
MDL Number:
MFCD00924333
MOL File:
151308-34-8.mol
TDS File:
TDS
Last updated:2026-04-24 14:58:52
Product description Number Pack Size Price
Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH FC108692 250ug $900
Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH FC108692 100ug $900
Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH FC108692 50ug $900
Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH FC108692 500ug $1410
Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH FC108692 1000ug $2470
More product size

RES-701-1 Properties

Density 1.50±0.1 g/cm3(Predicted)
storage temp. −20°C
pka 3.35±0.10(Predicted)

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

RES-701-1 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FC108692 Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH 151308-34-8 250ug $900 2026-06-04 Buy
Biosynth FC108692 Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH 151308-34-8 100ug $900 2026-06-04 Buy
Biosynth FC108692 Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH 151308-34-8 50ug $900 2026-06-04 Buy
Biosynth FC108692 Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH 151308-34-8 500ug $1410 2026-06-04 Buy
Biosynth FC108692 Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH 151308-34-8 1000ug $2470 2026-06-04 Buy
Product number Packaging Price Buy
FC108692 250ug $900 Buy
FC108692 100ug $900 Buy
FC108692 50ug $900 Buy
FC108692 500ug $1410 Buy
FC108692 1000ug $2470 Buy

RES-701-1 Chemical Properties,Uses,Production

Uses

RES-701-1 is a cyclic peptide composed of 16 common L-amino acids, acting as a specific antagonist for the ETB receptor. RES-701-1 can inhibit the binding of 125I-ET-1 (125I-labeled Endothelin (ET)-1) to the ETB receptor, with an IC50 value of 10 nM[1][2].

IC 50

ETB: 10 nM (IC50)

References

[1] Tanaka T, et al. RES-701-1, a novel, potent, endothelin type B receptor-selective antagonist of microbial origin. Mol Pharmacol. 1994 Apr;45(4):724-30. PMID:8183252
[2] Yamasaki M, et al. RES-701-1, a novel and selective endothelin type B receptor antagonist produced by Streptomyces sp. RE-701 II. Determination of the primary sequence[J]. The Journal of Antibiotics, 1994, 47(3): 276-280. DOI:10.7164/antibiotics.47.276

RES-701-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH RES-701-1 cyclo(gly-asn-trp-his-gly-thr-ala-pro-*B-asp)-thr GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH L-Tryptophan, glycyl-L-asparaginyl-L-tryptophyl-L-histidylglycyl-L-threonyl-L-alanyl-L-prolyl-L-α-aspartyl-L-tryptophyl-L-phenylalanyl-L-phenylalanyl-L-asparaginyl-L-tyrosyl-L-tyrosyl-, (9→1)-lactam RES-701-1 USP/EP/BP 151308-34-8 C103H115N23O23