RES-701-1
- CAS No.
- 151308-34-8
- Chemical Name:
- RES-701-1
- Synonyms
- RES-701-1;RES-701-1 USP/EP/BP;cyclo(gly-asn-trp-his-gly-thr-ala-pro-*B-asp)-thr;GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP;GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH;CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH;CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP;CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH;L-Tryptophan, glycyl-L-asparaginyl-L-tryptophyl-L-histidylglycyl-L-threonyl-L-alanyl-L-prolyl-L-α-aspartyl-L-tryptophyl-L-phenylalanyl-L-phenylalanyl-L-asparaginyl-L-tyrosyl-L-tyrosyl-, (9→1)-lactam
- CBNumber:
- CB7301326
- Molecular Formula:
- C103H115N23O23
- Molecular Weight:
- 2043.16
- MDL Number:
- MFCD00924333
- MOL File:
- 151308-34-8.mol
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
RES-701-1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | VAC-00439 | RES-701-1 | 1mg | $178.48 | 2026-06-05 | Buy | |
| Biosynth | VAC-00439 | RES-701-1 | 5mg | $535.45 | 2026-06-05 | Buy | |
| Biosynth | VAC-00439 | RES-701-1 | 10mg | $892.4 | 2026-06-05 | Buy | |
| Biosynth | FC108692 | Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH | 151308-34-8 | 250ug | $900 | 2026-06-04 | Buy |
| Biosynth | FC108692 | Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH | 151308-34-8 | 100ug | $900 | 2026-06-04 | Buy |
RES-701-1 Chemical Properties,Uses,Production
Uses
RES-701-1 is a cyclic peptide composed of 16 common L-amino acids, acting as a specific antagonist for the ETB receptor. RES-701-1 can inhibit the binding of 125I-ET-1 (125I-labeled Endothelin (ET)-1) to the ETB receptor, with an IC50 value of 10 nM[1][2].
IC 50
ETB: 10 nM (IC50)
References
[1] Tanaka T, et al. RES-701-1, a novel, potent, endothelin type B receptor-selective antagonist of microbial origin. Mol Pharmacol. 1994 Apr;45(4):724-30. PMID:8183252
[2] Yamasaki M, et al. RES-701-1, a novel and selective endothelin type B receptor antagonist produced by Streptomyces sp. RE-701 II. Determination of the primary sequence[J]. The Journal of Antibiotics, 1994, 47(3): 276-280. DOI:10.7164/antibiotics.47.276
RES-701-1 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alabiochem Tech.Co., Ltd. | 512-58900862 400-0707518 | sales@alabiochem.com | China | 988 | 59 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 1010 | 55 |
| Creative Peptides | info@creative-peptides.com | United States | 6083 | 56 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Changyan Chem & Tech Co., Ltd. | 021-20242659 18930833303 | sales@changyanchem.cn | China | 4998 | 55 |
| Alabiotech Inc. | 001-619-354-5251 | sales@alabiotech-e.com | United States | 972 | 60 |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
