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ChemicalBook >> CAS DataBase List >>1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride

1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride

1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride Structure
1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride structure
CAS No.
36273-11-7
Chemical Name:
1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride
Synonyms
1-(Chloromethyl)-1,4-diazabicyclo[2.2.2]octan-1-ium chloride;1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride;4-Aza-1-azoniabicyclo[2.2.2]octane,1-(chloromethyl)-,chloride(1:1)
CBNumber:
CB73037714
Molecular Formula:
C7H14Cl2N2
Molecular Weight:
197.1
MDL Number:
MFCD20623369
MOL File:
36273-11-7.mol
MSDS File:
SDS
Last updated:2026-05-28 02:50:00
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1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride Properties

storage temp. Inert atmosphere,Room Temperature
Appearance White to off-white Solid
EPA Substance Registry System 4-Aza-1-azoniabicyclo[2.2.2]octane, 1-(chloromethyl)-, chloride (36273-11-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
TSCA  TSCA listed

1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Synthonix C43873 1-(Chloromethyl)-1,4-diazabicyclo[2.2.2]octan-1-ium chloride 97% 36273-11-7 100mg $24 2026-05-06 Buy
Synthonix C43873 1-(Chloromethyl)-1,4-diazabicyclo[2.2.2]octan-1-ium chloride 97% 36273-11-7 250mg $30 2026-05-06 Buy
Synthonix C43873 1-(Chloromethyl)-1,4-diazabicyclo[2.2.2]octan-1-ium chloride 97% 36273-11-7 1g $100 2026-05-06 Buy
aablocks AA0032GB 1-(Chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride 97% 36273-11-7 100mg $12 2026-05-28 Buy
aablocks AA0032GB 1-(Chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride 97% 36273-11-7 250mg $23 2026-05-28 Buy
Product number Packaging Price Buy
C43873 100mg $24 Buy
C43873 250mg $30 Buy
C43873 1g $100 Buy
AA0032GB 100mg $12 Buy
AA0032GB 250mg $23 Buy

1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride Chemical Properties, Uses, Production

Synthesis

Triethylenediamine

280-57-9

Dichloromethane

75-09-2

1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride

36273-11-7

General procedure for the synthesis of 1-(chloromethyl)-1,4-diazabicyclo[2.2.2]octan-1-ium chloride from triethylenediamine (DABCO) and dichloromethane: 1,4-diazabicyclo[2.2.2]octane (DABCO) (11.2 g, 0.1 mol) was dissolved in 30 mL of dichloromethane, and the reaction mixture was stirred under reflux conditions overnight. Upon completion of the reaction, a white solid was obtained by filtration, washed with dichloromethane (2 x 20 mL) and dried under vacuum to afford 1-(chloromethyl)-1,4-diazabicyclo[2.2.2]octan-1-ium chloride in 96% (18.7 g) yield. The product 1-(chloromethyl)-1,4-diazabicyclo[2.2.2]octan-1-ium chloride was characterized as follows: 1H-NMR (500 MHz, D2O) δ 4.97 (s, 2H), 3.40 (t, J = 7.0 Hz, 6H), 3.10 (t, J = 7.5 Hz, 6H); 13C-NMR (125 MHz, D2O) δ 68.2, 51.1, 43.9.

References

[1] Tetrahedron Letters, 2014, vol. 55, # 49, p. 6643 - 6646
[2] Journal of Organic Chemistry, 2017, vol. 82, # 22, p. 11792 - 11798
[3] Journal of Fluorine Chemistry, 1996, vol. 81, # 1, p. 43 - 50
[4] Chinese Journal of Chemistry, 2015, vol. 33, # 2, p. 220 - 224
[5] Patent: WO2014/68341, 2014, A2. Location in patent: Page/Page column 39

1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride synthesis

280-57-9
75-09-2
36273-11-7
Synthesis of 1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride from Triethylenediamine and Dichloromethane

1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride Preparation Products And Raw materials

Raw materials

Dichloromethane Triethylenediamine

Preparation Products

1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride Suppliers

Global Suppliers ( 22)
Supplier Tel Email Country ProdList Advantage
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
DebyeTec.com Inc. 18086626237 18086626237 2693528373@qq.com China 2936 56
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Henan Alfachem Co.,Ltd. 0371-55051623 18137891487 3983243027@qq.com China 9974 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 40000 58
Shanxi Xuanran Import and Export Trade Co., Ltd. +8617735180244 mike_yan@xuanranglobal.com CHINA 4011 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49299 58
Shanghai Zhikai Pharmaceutical Technology Co., Ltd. 15000251104 kkpp1986@163.com China 281 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
Supplier Advantage
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
Bide Pharmatech Ltd. 60
DebyeTec.com Inc. 56
Amadis Chemical Company Limited 58
Henan Alfachem Co.,Ltd. 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 58
Shanxi Xuanran Import and Export Trade Co., Ltd. 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 58
Shanghai Zhikai Pharmaceutical Technology Co., Ltd. 58
Energy Chemical 58

1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride Spectrum

1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride(36273-11-7)1HNMR

36273-11-7 (1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride) Related Search:

4-Aza-1-azoniabicyclo[2.2.2]octane,1-methyl-, iodide (1:1) 4-Aza-1-azoniabicyclo[2.2.2]octane, 1-methyl-, tetrafluoroborate(1-) (1:1) 1-Hexyl-1,4-diazabicyclo[2.2.2]octan-1-ium Iodide 4-Aza-1-azoniabicyclo[2.2.2]octane,1-(chloromethyl)-,tetrafluoroborate(1-) 4-Aza-1-azoniabicyclo[2.2.2]octane, 1-methyl-, chloride (1:1)
1,4-dimethyl-1,4-diazabicyclo[2.2.2]octane-1,4-diium chloride

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1-(chloromethyl)-4-aza-1-azonia bicyclo[2.2.2]octane chloride 1-(Chloromethyl)-1,4-diazabicyclo[2.2.2]octan-1-ium chloride 4-Aza-1-azoniabicyclo[2.2.2]octane,1-(chloromethyl)-,chloride(1:1) 36273-11-7 C7H14ClN2Cl