Propargyl-PEG5-t-butyl ester
- CAS No.
- 1245823-50-0
- Chemical Name:
- Propargyl-PEG5-t-butyl ester
- Synonyms
- Propargyl-PEG5-COOtBu;PropargylPEG5-tBu ester;Propargyl-PEG4-C2-COOtBu;Alkyne-PEG5-CH2CH2COOtBu;Propargyl-PEG4-CH2CH2-Boc;PROPARGYL-PEG5-CH2CH2COOTBU;Propargyl-PEG5-t-butyl ester;1-Boc-3,6,9,12,15-pentaoxaoctadec-17-yne;tert-butyl 4,7,10,13,16-pentaoxanonadec-18-ynoate;4,7,10,13,16-Pentaoxanonadec-18-ynoic acid, 1,1-dimethylethyl ester
- CBNumber:
- CB73048734
- Molecular Formula:
- C18H32O7
- Molecular Weight:
- 360.44
- MDL Number:
- MFCD22201534
- MOL File:
- 1245823-50-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
Propargyl-PEG5-t-butyl ester price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0106532 | Propargyl-PEG4-CH2CH2-Boc ≥97% | 1245823-50-0 | 250mg | $30 | 2026-06-04 | Buy |
| ChemScene | CS-0106532 | Propargyl-PEG4-CH2CH2-Boc ≥97% | 1245823-50-0 | 500mg | $60 | 2026-06-04 | Buy |
| ChemScene | CS-0106532 | Propargyl-PEG4-CH2CH2-Boc ≥97% | 1245823-50-0 | 1g | $94 | 2026-06-04 | Buy |
| ChemScene | CS-0106532 | Propargyl-PEG4-CH2CH2-Boc ≥97% | 1245823-50-0 | 5g | $508 | 2026-06-04 | Buy |
| Apolloscientific | BIPG1746 | Propargyl-PEG5-t-butyl ester 95% | 1245823-50-0 | 250mg | $37 | 2026-06-04 | Buy |
Propargyl-PEG5-t-butyl ester Chemical Properties,Uses,Production
Description
Propargyl-PEG5-t-butyl ester has one of the functional groups protected by t-butyl group. The protection can be removed under acidic conditions. The propargyl group forms triazole linkages with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. The PEG units help improving the water-solubility of the molecule in aqueous media.
Uses
Propargyl-PEG4-CH2CH2-Boc is a non-cleavable ADC linker that can be used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-CH2CH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
Non-cleavable Linker; Alkyl/ether
References
[1] Zhang H, et al. Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors. Bioconjug Chem. 2018 Apr 18;29(4):1266-1275. DOI:10.1021/acs.bioconjchem.8b00047
Propargyl-PEG5-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alabiochem Tech.Co., Ltd. | 512-58900862 400-0707518 | sales@alabiochem.com | China | 988 | 59 |
| Chengdu Pukang Biotechnology Co., Ltd | 18217049878 | cassie.gao@pu-kang.com | China | 479 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | sales@huatengsci.com | China | 5869 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Zhengzhou Acme Chemical Co., Ltd. | 0371-0371-55629727 13323845623 | 2885676761@qq.com | China | 9948 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28763 | 58 |
| Jiaxing Deyi Chemical Co., Ltd. | 86-0573-85866609 18367600069 | 945717149@qq.com | China | 9507 | 58 |
| Aikon International Limited | 025-58851090 13913916777 | sales01@aikonchem.com | China | 15947 | 58 |
View Lastest Price from Propargyl-PEG5-t-butyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | Propargyl-PEG5-COOtBu
1245823-50-0
|
1g | 98% | 1g/bottle, 10g/bottle, 100g/bottle | XIAMEN SINOPEG BIOTECH CO., LTD. | ||
 |
2026-05-11 | Propargyl-PEG4-CH2CH2-Boc
1245823-50-0
|
10g | TargetMol Chemicals Inc. | ||||
 |
2025-06-07 | Propargyl-PEG5-COOtBu
1245823-50-0
|
1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- Propargyl-PEG5-COOtBu
1245823-50-0
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
-
- Propargyl-PEG4-CH2CH2-Boc
1245823-50-0
- $0.00
- TargetMol Chemicals Inc.
-
- Propargyl-PEG5-COOtBu
1245823-50-0
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
