Boronic acid, B-(2-formyl-3-methoxyphenyl)-
- CAS No.
- 958030-46-1
- Chemical Name:
- Boronic acid, B-(2-formyl-3-methoxyphenyl)-
- Synonyms
- (2-Formyl-3-methoxyphenyl)boronic acid;(3-methoxy-2-formyl-phenyl)boronic acid;Boronic acid, B-(2-formyl-3-methoxyphenyl)-
- CBNumber:
- CB73059138
- Molecular Formula:
- C8H9BO4
- Molecular Weight:
- 179.97
- MDL Number:
- MFCD01319042
- MOL File:
- 958030-46-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2931900090 |
Boronic acid, B-(2-formyl-3-methoxyphenyl)- price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 295161 | (2-Formyl-3-methoxyphenyl)boronic acid | 958030-46-1 | 1.00g | $71 | 2026-05-19 | Buy |
| Matrix Scientific | 295161 | (2-Formyl-3-methoxyphenyl)boronic acid | 958030-46-1 | 5.00g | $272 | 2026-05-19 | Buy |
| Matrix Scientific | 295161 | (2-Formyl-3-methoxyphenyl)boronic acid | 958030-46-1 | 10.00g | $472 | 2026-05-19 | Buy |
| Synthonix | F49417 | (2-Formyl-3-methoxyphenyl)boronic acid 98% | 958030-46-1 | 100mg | $25 | 2026-05-06 | Buy |
| Synthonix | F49417 | (2-Formyl-3-methoxyphenyl)boronic acid 98% | 958030-46-1 | 250mg | $31 | 2026-05-06 | Buy |
Boronic acid, B-(2-formyl-3-methoxyphenyl)- Chemical Properties, Uses, Production
Synthesis
5419-55-6
958030-46-1
General procedure for the synthesis of 3-methoxy-2-formylphenylboronic acid from triisopropyl borate: tert-butyllithium solution (9.0 mL, 1.7 M in pentane) was added dropwise to a stirring solution of 2-(2-methoxyphenyl)-1,3-dimethylimidazolidinium (2.0 g, 9.8 mmol) in tetrahydrofuran (5 mL) under nitrogen protection, and the reaction temperature was maintained at -10 °C, followed by continued stirring at 0-5 °C for 2 hours. Upon completion of the reaction, the mixture was cooled to -50 °C and triisopropyl borate (3.5 mL, 15 mmol) was slowly added. The reaction solution was gradually warmed to 0 °C over 3 hours. 2N hydrochloric acid (120 mL) was added at 0 °C and stirred for 30 min. The reaction mixture was returned to room temperature and diluted with ethyl acetate. The organic phase was washed sequentially with 1N hydrochloric acid (2×) and saturated saline, dried over anhydrous sodium sulfate and concentrated to give a yellow crude product. The crude product was purified by reversed-phase high-performance liquid chromatography, and after removal of the solvent, 1.3 g of 3-methoxy-2-formylphenylboronic acid in the form of a light yellow solid was obtained in 75% yield.ESI-MS m/e 177 (MH+).
References
[1] Patent: US2007/270406, 2007, A1. Location in patent: Page/Page column 31
Boronic acid, B-(2-formyl-3-methoxyphenyl)- Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9510 | 58 |
| Shanghai ShiXian Chemical Technology Co., Ltd. | 13764359345 | 990877971@qq.com | China | 1917 | 50 |
| Shanghai Rong Lin Medical Technology Co., Ltd. | 18602194589 | lincy-110@163.com | China | 873 | 58 |
| Changzhou Hopschain Chemical Co.,Ltd. | 85528066 13775048983 | sales@hopschem.com | China | 31548 | 55 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
| Cool Pharm, Ltd | 021-58581007 18019463053 | sales@coolpharm.com | China | 9999 | 58 |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49299 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 13675144456 | sean.lv@synzest.com | China | 11432 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39796 | 58 |
