1-(Trifluoroacetyl)imidazole
- CAS No.
- 1546-79-8
- Chemical Name:
- 1-(Trifluoroacetyl)imidazole
- Synonyms
- TRIFLUOROACETYLIMIDAZOLE;TFAI;N-TRIFLUOROACETYLIMIDAZOLE;TFBI;TrifluorobutyrliMidazole;TrifluorobutyryliMidazole;1-(TRIFLUOROACETYL)IMIDAZOLE;1-(Trifluoroacetyl)imidazole 98%;1-(trifluoroacetyl)-1h-imidazole;N-Trifluoroacetylimidazole, 98+%
- CBNumber:
- CB7308204
- Molecular Formula:
- C5H3F3N2O
- Molecular Weight:
- 164.09
- MDL Number:
- MFCD00014501
- MOL File:
- 1546-79-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1-(Trifluoroacetyl)imidazole 98% | 346128 | 10g | $108 |
| 1-(Trifluoroacetyl)imidazole 98% | 346128 | 1g | $31.5 |
| 1-(Trifluoroacetyl)imidazole >98.0%(T) | T0670 | 5g | $43 |
| 1-(Trifluoroacetyl)imidazole >98.0%(T) | T0670 | 25g | $218 |
| 1-(Trifluoroacetyl)imidazole | FT60417 | 5g | $150 |
| More product size | |||
| Boiling point | 137 °C(lit.) |
|---|---|
| Density | 1.442 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 113 °F |
| storage temp. | 2-8°C |
| solubility | sol most common solvents, e.g. ether, THF. |
| pka | 0.78±0.10(Predicted) |
| form | clear liquid |
| color | Colorless to Yellow to Orange |
| Specific Gravity | 1.442 |
| Water Solubility | reacts |
| Sensitive | Moisture Sensitive |
| BRN | 608904 |
| InChI | 1S/C5H3F3N2O/c6-5(7,8)4(11)10-2-1-9-3-10/h1-3H |
| InChIKey | SINBGNJPYWNUQI-UHFFFAOYSA-N |
| SMILES | FC(F)(F)C(=O)n1ccnc1 |
| CAS DataBase Reference | 1546-79-8(CAS DataBase Reference) |
| FDA UNII | 8C6041OW3I |
| NIST Chemistry Reference | N-Trifluoroacetylimidazole(1546-79-8) |
| UNSPSC Code | 12352005 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226-H315-H319-H335 | |||||||||
| Precautionary statements | P210-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,F,C | |||||||||
| Risk Statements | 10-36/37/38-34-22 | |||||||||
| Safety Statements | 26-36/37-45-36/37/39-16 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| Hazard Note | Flammable/Moisture Sensitive/Keep Cold | |||||||||
| TSCA | T | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29332900 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Flam. Liq. 3 Skin Irrit. 2 STOT SE 3 |
|||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
1-(Trifluoroacetyl)imidazole price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 346128 | 1-(Trifluoroacetyl)imidazole 98% | 1546-79-8 | 10g | $108 | 2026-04-30 | Buy |
| Sigma-Aldrich | 346128 | 1-(Trifluoroacetyl)imidazole 98% | 1546-79-8 | 1g | $31.5 | 2023-06-20 | Buy |
| TCI Chemical | T0670 | 1-(Trifluoroacetyl)imidazole >98.0%(T) | 1546-79-8 | 5g | $43 | 2026-04-30 | Buy |
| TCI Chemical | T0670 | 1-(Trifluoroacetyl)imidazole >98.0%(T) | 1546-79-8 | 25g | $218 | 2026-04-30 | Buy |
| Biosynth | FT60417 | 1-(Trifluoroacetyl)imidazole | 1546-79-8 | 5g | $150 | 2026-06-04 | Buy |
1-(Trifluoroacetyl)imidazole Chemical Properties,Uses,Production
Chemical Properties
Colorless to pink liquid
Uses
1-(Trifluoroacetyl)imidazole was used as a derivating agent to sequentially derivatize functional groups like amino groups, in a study demonstrating trimethylsilyl esters of aromatic and aliphatic sulfonic acids.
Preparation
N,N′-Carbonyldiimidazole (20.5 g) is dissolved in 100 ml of dry THF and treated dropwise with 28.8 g of Trifluoroacetic Acid in 80 mL of dry THF. The resulting solution is cooled for several hours. Removal of the solvent and distillation of the filtrate gives 14.4 g of material. Alternatively, Imidazole (25.8 g) in 120 mL of dried THF is treated dropwise, with cooling, with 39.9 g of Trifluoroacetic Anhydride in 50 mL of dried THF. Filtration, removal of solvent, and distillation gives 24.8 g of 1-(Trifluoroacetyl)imidazole.
General Description
1-(Trifluoroacetyl)imidazole is a derivatizing reagent.
reaction suitability
reagent type: derivatization reagent
reaction type: Acylations
storage
store under nitrogen, carefully excluding water. Irritant; moisture sensitive; keep cold; flammable.
1-(Trifluoroacetyl)imidazole Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-17392712779 | 1097@dideu.com | China | 3989 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21531 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8618017249410 | jack.li@time-chemicals.com | China | 1796 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| CD Chemical Group Limited | +86-13651442114 | info@codchem.com | China | 17253 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-17732866630 | mina@chuanghaibio.com | China | 18114 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; +86-85511178 | peter68@ptchemgroup.com | China | 35405 | 58 |
View Lastest Price from 1-(Trifluoroacetyl)imidazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | 1-(Trifluoroacetyl)imidazole
1546-79-8
|
1KG | 99.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-12-24 | 1-(Trifluoroacetyl)imidazole
1546-79-8
|
1KG | 98.0% | 10 | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2019-07-06 | 1-(Trifluoroacetyl)imidazole
1546-79-8
|
$1.00 | 1kg | 98% | 200KG | Career Henan Chemical Co |
-
- 1-(Trifluoroacetyl)imidazole
1546-79-8
- 99.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 1-(Trifluoroacetyl)imidazole
1546-79-8
- $0.10
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 1-(Trifluoroacetyl)imidazole
1546-79-8
- $1.00
- 98%
- Career Henan Chemical Co
