4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride
- CAS No.
- 893421-54-0
- Chemical Name:
- 4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride
- Synonyms
- Imidafenacin hydrochloride;4-(2-methyl-1-imidazolyl)-2,2-diphenylbutanamidehydrochloride;4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride
- CBNumber:
- CB73137096
- Molecular Formula:
- C20H22ClN3O
- Molecular Weight:
- 355.86118
- MDL Number:
- MFCD20489106
- MOL File:
- 893421-54-0.mol
- TDS File:
- TDS
| storage temp. | 2-8°C |
|---|---|
| solubility | H2O: soluble15mg/mL, clear |
| form | powder |
| color | white to beige |
| Water Solubility | H2O: 15mg/mL, clear |
| InChIKey | SQKXYSGRELMAAU-UHFFFAOYSA-N |
| SMILES | [n]3(c(ncc3)C)CCC(c2ccccc2)(c1ccccc1)C(=O)N |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1821 | Imidafenacin hydrochloride ≥95% (HPLC) | 893421-54-0 | 25mg | $434 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML1821 | Imidafenacin hydrochloride ≥95% (HPLC) | 893421-54-0 | 5mg | $107 | 2023-06-20 | Buy |
| Biosynth | TKB42154 | Imidafenacin hydrochloride | 893421-54-0 | 25mg | $801.75 | 2026-06-05 | Buy |
| Biosynth | TKB42154 | Imidafenacin hydrochloride | 893421-54-0 | 50mg | $1282.5 | 2026-06-05 | Buy |
| Biosynth | TKB42154 | Imidafenacin hydrochloride | 893421-54-0 | 100mg | $1785 | 2026-06-05 | Buy |
4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride Chemical Properties, Uses, Production
Uses
Imidafenacin hydrochloride is a potent and selective inhibitor of M3 receptors with a Kb of 0.317 nM[1].
Biological Activity
Imidafenacin exhibits anticholinergic properties. It also has potential therapeutic effects on prostatic hyperplasia.', 'Imidafenacin is a potent antimuscarinic agent th at exhibits selectivity toward muscarinic M3 receptors with Kb of 0.317 nM. Imidafenacin is used for treating overactive bladder.
References
[1] Miyachi H, et al. Synthesis and antimuscarinic activity of a series of 4-(1-Imidazolyl)-2,2-diphenylbutyramides: discovery of potent and subtype-selective antimuscarinic agents. Bioorg Med Chem. 1999 Jun;7(6):1151-61. DOI:10.1016/s0968-0896(99)00003-6
[2] Yamazaki T, et al. Imidafenacin has no influence on learning in nucleus basalis of Meynert-lesioned rats. Naunyn Schmiedebergs Arch Pharmacol. 2013 Dec;386(12):1095-102. DOI:10.1007/s00210-013-0910-z
4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei widely chemical technology Co., Ltd. | 027-83991130 18627774460 | 1718093273@QQ.COM | China | 1617 | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-61109150 | sales@tcisct.com | China | 29717 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| Hubei widely chemical technology Co., Ltd. | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
