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(±)16(17)-EpDPA

CAS No.
155073-46-4
Chemical Name:
(±)16(17)-EpDPA
Synonyms
(±)16(17)-EpDPA;BCTXZWCPBLWCRV-QCAYAECISA-N;(±)16(17)-EpDPA MaxSpec Standard;16,(17)-Epoxy-4(Z),7(Z),10(Z),13(Z),19(Z)-DPA;4,7,10,13-Pentadecatetraenoic acid, 15-[(2R,3S)-3-(2Z)-2-penten-1-yl-2-oxiranyl]-, (4Z,7Z,10Z,13Z)-rel-
CBNumber:
CB73152406
Molecular Formula:
C22H32O3
Molecular Weight:
344.49
MDL Number:
MOL File:
155073-46-4.mol
MSDS File:
SDS
Last updated:2026-05-28 03:52:39

(±)16(17)-EpDPA Properties

Boiling point 462.5±33.0 °C(Predicted)
Density 0.994±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml
pka 4.58±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

(±)16(17)-EpDPA price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10174 (±)16(17)-EpDPA ≥90% 155073-46-4 25μg $46 2026-04-30 Buy
Cayman Chemical 10174 (±)16(17)-EpDPA ≥90% 155073-46-4 50μg $86 2026-04-30 Buy
Cayman Chemical 10174 (±)16(17)-EpDPA ≥90% 155073-46-4 100μg $160 2026-04-30 Buy
Cayman Chemical 10174 (±)16(17)-EpDPA ≥90% 155073-46-4 500μg $707 2026-04-30 Buy
ChemScene CS-1098672 (±)16(17)-EpDPA 155073-46-4 100μg(290.28μM*1mLinEthanol) $346 2026-06-04 Buy
Product number Packaging Price Buy
10174 25μg $46 Buy
10174 50μg $86 Buy
10174 100μg $160 Buy
10174 500μg $707 Buy
CS-1098672 100μg(290.28μM*1mLinEthanol) $346 Buy

(±)16(17)-EpDPA Chemical Properties, Uses, Production

Description

EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.1,2 Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids produces epoxides such as (±)14(15)-EET which are prime candidates for the actual active mediator.3 However, the CYP450 metabolites of eicosapentaenoic acid (EPA; ) and docosahexaenoic acid (DHA; ) have been little studied relative to arachidonate epoxygenase metabolites. (±)16(17)-EpDPA is the DHA homolog of (±)14(15)-EpETrE, derived via epoxidation of the 16,17-double bond of DHA. The EDHF activity of (±)16(17)-EpDPA has not yet been determined. The epoxygenase metabolites of DHA have also been detected in a mouse inflammation model.4

Uses

(±)16(17)-EpDPA is the DHA homolog of (±)14(15)-EpETrE, derived via epoxidation of the 16,17-double bond of DHA.

References

1. Chataigneau, T., Félétou, M., Duhault, J., et al. Epoxyeicosatrienoic acids, potassium channel blockers, and endothelium-dependent hyperpolarization in the guinea-pig carotid artery Br. J. Pharmacol. 123(3),574-580(1998).
2. Fisslthaler, B., Popp, R., Kiss, L., et al. Cytochrome P450 2C is an EDHF synthase in coronary arteries Nature 401(6752),493-497(1999).
3. Baron, A., Frieden, M., and Bény, J.L. Epoxyeicosatrienoic acids activate a high-conductance, Ca2+-dependent K+ channel on pig coronary artery endothelial cells J. Physiol. 504(Pt 3),537-543(1997).
4. Serhan, C.N., Hong, S., Gronert, K., et al. Resolvins: A family of bioactive products of ω-3 fatty acid transformation circuits by aspirin treatment that counter proinflammation signals J. Exp. Med. 196(8),1025-1037(2002).

(±)16(17)-EpDPA Preparation Products And Raw materials

Raw materials

Preparation Products

(±)16(17)-EpDPA Suppliers

Global Suppliers ( 25)
Supplier Tel Email Country ProdList Advantage
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1978 58
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9170 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
amyjet 4006800868;027-59626688 18771149750 sales@amyjet.com China 2909 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
SHANGHAI ZZBIO CO., LTD. 18019219489 18901678489 tech@zzbioco.com China 12062 58

View Latest Price from (±)16(17)-EpDPA manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(±)16(17)-EpDPA pictures 2026-04-21 (±)16(17)-EpDPA
155073-46-4
10g TargetMol Chemicals Inc.
(±)16(17)-EpDPA BCTXZWCPBLWCRV-QCAYAECISA-N (±)16(17)-EpDPA MaxSpec Standard 4,7,10,13-Pentadecatetraenoic acid, 15-[(2R,3S)-3-(2Z)-2-penten-1-yl-2-oxiranyl]-, (4Z,7Z,10Z,13Z)-rel- 16,(17)-Epoxy-4(Z),7(Z),10(Z),13(Z),19(Z)-DPA 155073-46-4