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Commendamide

CAS No.
193825-78-4
Chemical Name:
Commendamide
Synonyms
Commendamide;N-(3-hydroxy-1-oxohexadecyl)-glycine;Glycine, N-(3-hydroxy-1-oxohexadecyl)-;Commendamide (N-acyl-3-hydroxypalmitoyl-Glycine)
CBNumber:
CB73152592
Molecular Formula:
C18H35NO4
Molecular Weight:
329.47
MDL Number:
MFCD30738318
MOL File:
193825-78-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 16:31:51

Commendamide Properties

Boiling point 532.5±35.0 °C(Predicted)
Density 1.016±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.3mg/ml; DMSO: 20 mg/ml; Ethanol: 15 mg/ml
form A crystalline solid
pka 3.51±0.10(Predicted)

Commendamide price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 18421 Commendamide ≥95% 193825-78-4 500μg $45 2026-04-30 Buy
Cayman Chemical 18421 Commendamide ≥95% 193825-78-4 1mg $86 2026-04-30 Buy
Cayman Chemical 18421 Commendamide ≥95% 193825-78-4 5mg $360 2026-04-30 Buy
Cayman Chemical 18421 Commendamide ≥95% 193825-78-4 10mg $630 2026-04-30 Buy
ChemScene CS-0068522 Commendamide 193825-78-4 1mg $245 2026-06-04 Buy
Product number Packaging Price Buy
18421 500μg $45 Buy
18421 1mg $86 Buy
18421 5mg $360 Buy
18421 10mg $630 Buy
CS-0068522 1mg $245 Buy

Commendamide Chemical Properties, Uses, Production

Description

Commendamide is a natural bacterial product that was discovered in a screen for commensal bacteria effector genes (Cbegs).1 Cbeg12 is a bacterial effector gene that encodes for its production. Commendamide is structurally similar to long-chain N-acyl-amides, which commonly signal, in mammals, through G protein-coupled receptors. Commendamide activates GPR132 (also known as G2A) with an EC50 value of 11.8 μM.1

Uses

Commendamide is a GPCR G2A/GPR132 agonist (EC50: 11.8 μM). Commendamide can be used for research of autoimmunity and atherosclerosis[1].

Definition

ChEBI: N-(3-Hydroxy-1-oxohexadecyl)-glycine is a N-acyl-amino acid.

References

1. Cohen, L.J., Kang, H.S., Chu, J., et al. Functional metagenomic discovery of bacterial effectors in the human microbiome and isolation of commendamide, a GPCR G2A/132 agonist Proc. Natl. Acad. Sci. USA 112(35),E4825-E4834(2015).

Commendamide Preparation Products And Raw materials

Raw materials

Preparation Products

Commendamide Suppliers

Global Suppliers ( 15)
Supplier Tel Email Country ProdList Advantage
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 15775 55
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Changzhou Yourui Pharmaceutical Technology Co., Ltd 18168818882 877458914@qq.com China 8663 58

View Latest Price from Commendamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Commendamide pictures 2026-05-11 Commendamide
193825-78-4
$246.00-1780.00 10g TargetMol Chemicals Inc.
  • Commendamide pictures
  • Commendamide
    193825-78-4
  • $246.00-1780.00
  • TargetMol Chemicals Inc.

193825-78-4 (Commendamide) Related Search:

Commendamide Glycine, N-(3-hydroxy-1-oxohexadecyl)- N-(3-hydroxy-1-oxohexadecyl)-glycine Commendamide (N-acyl-3-hydroxypalmitoyl-Glycine) 193825-78-4